Anahita Rouzé
A5042987943- Respiratory Support and Mechanisms
- Nosocomial Infections in ICU
- Pneumonia and Respiratory Infections
- Intensive Care Unit Cognitive Disorders
- Airway Management and Intubation Techniques
- Antifungal resistance and susceptibility
- Family and Patient Care in Intensive Care Units
- Cardiac Arrest and Resuscitation
- Antibiotic Use and Resistance
- Fungal Infections and Studies
- Neonatal Respiratory Health Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Sepsis Diagnosis and Treatment
- COVID-19 Clinical Research Studies
- Healthcare Decision-Making and Restraints
- Antibiotic Resistance in Bacteria
- Inhalation and Respiratory Drug Delivery
- Long-Term Effects of COVID-19
- Thermal Regulation in Medicine
- Pancreatitis Pathology and Treatment
- Medical and Biological Ozone Research
- Respiratory viral infections research
- SARS-CoV-2 and COVID-19 Research
- Ultrasound in Clinical Applications
- Plant Pathogens and Fungal Diseases
Inserm
2017-2025
Centre Hospitalier Universitaire de Lille
2016-2025
Université de Lille
2016-2025
Unité de Glycobiologie Structurale et Fonctionnelle
2021-2025
Centre National de la Recherche Scientifique
2021-2025
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2024
Centre Hospitalier Universitaire de Rennes
2022
Centre Hospitalier Universitaire de Nantes
2022
Université de Poitiers
2022
Bayer (United States)
2018
factor VIII ◼ pulmonary embolism thrombosis von Willebrand W e report a case series of patients with coronavirus disease 2019 (CO-VID-19) (PE) in our institution.Lille University Hospital is the tertiary care center for North France, second greatest French region population density (189 people per 1 km 2 ), also considered metabolic area high number overweight patients.The study was approved by institutional data protection authority Lille Hospital.Among 107 first consecutive confirmed...
Although patients with SARS-CoV-2 infection have several risk factors for ventilator-associated lower respiratory tract infections (VA-LRTI), the reported incidence of hospital-acquired is low. We aimed to determine relationship between pneumonia, as compared influenza pneumonia or no viral infection, and VA-LRTI.Multicenter retrospective European cohort performed in 36 ICUs. All adult receiving invasive mechanical ventilation > 48 h were eligible if they had: at ICU admission. VA-LRTI,...
<h3>Importance</h3> High-flow nasal oxygen may prevent postextubation respiratory failure in the intensive care unit (ICU). The combination of high-flow with noninvasive ventilation (NIV) be an optimal strategy to avoid reintubation. <h3>Objective</h3> To determine whether prophylactic NIV applied immediately after extubation could reduce rate reintubation, compared alone, patients at high risk ICU. <h3>Design, Setting, and Participants</h3> Multicenter randomized clinical trial conducted...
Spontaneous-breathing trials can be performed with the use of either pressure-support ventilation (PSV) or a T-piece. Whether PSV may result in shorter time to tracheal extubation than T-piece trials, without resulting higher risk reintubation, among patients who have high failure is unknown.In this multicenter, open-label trial, we randomly assigned had (i.e., were >65 years age an underlying chronic cardiac respiratory disease) undergo spontaneous-breathing (with level 8 cm water and no...
Patients with SARS-CoV-2 infection are at higher risk for ventilator-associated pneumonia (VAP). No study has evaluated the relationship between VAP and mortality in this population, or compared patients other populations. The main objective of our was to determine patients.Planned ancillary analysis a multicenter retrospective European cohort. diagnosed using clinical, radiological quantitative microbiological criteria. Univariable multivariable marginal Cox's regression models,...
Rationale: Early empirical antimicrobial treatment is frequently prescribed to critically ill patients with coronavirus disease (COVID-19) based on Surviving Sepsis Campaign guidelines.Objectives: We aimed determine the prevalence of early bacterial identification in intubated severe acute respiratory syndrome 2 (SARS-CoV-2) pneumonia, as compared influenza and characterize its microbiology impact outcomes.Methods: A multicenter retrospective European cohort was performed 36 ICUs. All adult...
Recent multicenter studies identified COVID-19 as a risk factor for invasive pulmonary aspergillosis (IPA). However, no large study has compared the incidence of IPA between and influenza patients.To determine putative in critically ill SARS-CoV-2 patients, with patients.This was planned ancillary analysis coVAPid retrospective European cohort. Consecutive adult patients requiring mechanical ventilation > 48 h pneumonia or were included. The 28-day cumulative IPA, based on Blot definition,...
Objectives: Ventilator-associated lower respiratory tract infections (VALRTIs) are among the most common ICU-acquired in patients receiving invasive mechanical ventilation (IMV). Immunocompromised may have a incidence of VALRTI when compared with nonimmunocompromised patients, but influence type immunosuppression on epidemiology has not been investigated. The study objectives were to assess association incidence, microbiology, and outcomes (ICU mortality, ICU length stay, duration IMV)...
Underinflation of tracheal cuff is a risk factor for microaspiration contaminated secretions and subsequent ventilator-associated pneumonia (VAP). The aim this collaborative meta-analysis individual participant data to determine the impact continuous control P on incidence VAP. Studies were identified by searching PubMed references relevant articles. Data from 3 prospective controlled trials (two randomized one quasi-randomized), which evaluated VAP, obtained pooled together. Three different...
Rationale: Although noninvasive ventilation (NIV) may prevent reintubation in patients at high risk of extubation failure ICUs, this oxygenation strategy has not been specifically assessed obese patients. Objectives: We hypothesized that NIV decrease the compared with high-flow nasal oxygen. Methods:Post hoc analysis a multicenter randomized controlled trial (not prespecified) comparing alternating oxygen versus alone after extubation, aim assessing effects according to patient body mass...
BackgroundHuman metapneumovirus (hMPV) is one of the leading respiratory viruses. This prospective observational study aimed to describe clinical features and outcomes hMPV-associated lower tract infections in adult inpatients.MethodsConsecutive patients admitted 31 participating centers with an acute infection a multiplex PCR positive for hMPV were included. A primary composite end point complicated course (hospital death and/or need invasive mechanical ventilation) was used.ResultsBetween...
The primary objective of this study was to determine the efficiency hydrogen peroxide (H₂O₂) techniques in disinfection ICU rooms contaminated with multidrug-resistant organisms (MDRO) after patient discharge. Secondary objectives included comparison a vaporizator (HPV, Bioquell) and an aerosolizer using H₂O₂, peracetic acid (aHPP, Anios) MDRO environmental disinfection, assessment toxicity these techniques.This prospective cross-over conducted five medical surgical ICUs located one...
The aim of this planned analysis the prospective multinational TAVeM database was to determine incidence, aetiology and impact on outcome ventilator-associated lower respiratory tract infections (VA-LRTI) in immunocompromised patients.All patients receiving mechanical ventilation for >48 h were included. Immunocompromised (n=663) compared with non-immunocompromised (n=2297).The incidence VA-LRTI significantly among than (16.6% versus 24.2%; sub-hazard ratio 0.65, 95% CI 0.53-0.80; p<0.0001)....
Despite the extensive use of high-flow nasal cannula (HFNC) therapy in intensive care units (ICU) for acute respiratory failure (ARF), its daily clinical practice has not been assessed. We designed a regional survey ICUs North-west France to evaluate ICU physicians' with HFNC.We sent an observational physicians from 34 French over 6-month period 2016-2017. The included questions regarding indications and expected efficiency HFNC, practical aspects (initiation, weaning) satisfaction....
Abstract Background The collapsibility index of the inferior vena cava (cIVC) has potential for predicting fluid responsiveness in spontaneously breathing patients, but a standardized approach measuring diameter yet to be established. aim was test accuracy different measurement sites predict patients with sepsis-related circulatory failure and examine influence manoeuvre. Results Among 81 included study, median Simplified Acute Physiologic Score II 34 (24; 42). Sepsis pulmonary origin 49...
The management of severe SARS-CoV-2 pneumonia, alongside logistical constraints, evolved between the first and subsequent COVID-19 waves. This study aimed to compare prevalence early bacterial pulmonary co-infections incidence ventilator-associated lower respiratory tract infections (VA-LRTI) across second waves pandemic, characterize their microbiology. Latter part a multicenter retrospective European cohort analysis conducted in 35 ICUs. Adult patients admitted for pneumonia requiring...