A5059976906- Mechanical Circulatory Support Devices
- Respiratory Support and Mechanisms
- Sepsis Diagnosis and Treatment
- Inflammation biomarkers and pathways
- Cardiac Arrest and Resuscitation
- Pancreatitis Pathology and Treatment
- COVID-19 Clinical Research Studies
- Apelin-related biomedical research
- Nosocomial Infections in ICU
- Antibiotics Pharmacokinetics and Efficacy
- Poisoning and overdose treatments
- Intensive Care Unit Cognitive Disorders
- Pelvic floor disorders treatments
- Case Reports on Hematomas
- Pneumocystis jirovecii pneumonia detection and treatment
- Fungal Infections and Studies
- Heart Failure Treatment and Management
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Pharmacovigilance and Adverse Drug Reactions
- Long-Term Effects of COVID-19
- Streptococcal Infections and Treatments
- Takotsubo Cardiomyopathy and Associated Phenomena
- Adolescent and Pediatric Healthcare
- Acute Kidney Injury Research
- Infectious Encephalopathies and Encephalitis
Centre Hospitalier Universitaire de Lille
2017-2023
Université de Lille
2013-2023
Lille Inflammation Research International Center
2022
Inserm
2022
Centre National de la Recherche Scientifique
2022
Unité de Glycobiologie Structurale et Fonctionnelle
2022
Centre Hospitalier Universitaire de Rennes
2022
Hôpital Pontchaillou
2022
Hôpital Roger Salengro
2017-2020
Centre Oscar Lambret
2020
factor VIII ◼ pulmonary embolism thrombosis von Willebrand W e report a case series of patients with coronavirus disease 2019 (CO-VID-19) (PE) in our institution.Lille University Hospital is the tertiary care center for North France, second greatest French region population density (189 people per 1 km 2 ), also considered metabolic area high number overweight patients.The study was approved by institutional data protection authority Lille Hospital.Among 107 first consecutive confirmed...
Abstract Background Both critically ill patients with coronavirus disease 2019 (COVID-19) and receiving extracorporeal membrane oxygenation (ECMO) support exhibit a high incidence of healthcare-associated infections (HAI). However, data on incidence, microbiology, resistance patterns, the impact HAI outcomes in ECMO for severe COVID-19 remain limited. We aimed to report microbiology evaluate ECMO-associated (ECMO-AI) in-hospital mortality. Methods For this study, we analyzed from 701...
Abstract Background The collapsibility index of the inferior vena cava (cIVC) has potential for predicting fluid responsiveness in spontaneously breathing patients, but a standardized approach measuring diameter yet to be established. aim was test accuracy different measurement sites predict patients with sepsis-related circulatory failure and examine influence manoeuvre. Results Among 81 included study, median Simplified Acute Physiologic Score II 34 (24; 42). Sepsis pulmonary origin 49...
We aimed to compare the outcomes of patients under veno-venous extracorporeal membrane oxygenation (V-V ECMO) for COVID-19-Acute Respiratory Distress Syndrome (CARDS) between first and second wave. From 1 March 2020 30 November 2020, fifty requiring a V-V ECMO support CARDS were included. Patient demographics, pre-ECMO, day one, three, seven on-ECMO data collected. The 90-day mortality was 11% higher during wave (18/26 (69%)) compared (14/24 (58%) (p = 0.423). During wave, all given steroids...
We investigated the potential hepatotoxicity of lopinavir/ritonavir recently used in treatment Severe Acute Respiratory Syndrome Coronavirus.This is a retrospective cohort critical patients teaching hospital: 12 treated with and 30 standard-of-care group.Elevation occurred more frequently (33% vs 6.7%).Caution advised regarding use most severe cases Coronavirus.
Predictive scores assessing the risk of respiratory failure in COVID-19 mostly focused on prediction early intubation. A combined assessment clinical parameters and biomarkers endotheliopathy could allow to predict late worsening acute (ARF), subsequently warranting intubation COVID-19. Retrospective single-center derivation (n = 92 subjects) validation cohorts 59 subjects), including severe patients with non-invasive support, were assessed for at least 48 h following intensive care unit...
Sodium lactate seemed to improve fluid balance and avoid overload. The objective of this study was determine if these beneficial effects can be at least partly explained by an improvement in disseminated intravascular coagulation (DIC)-associated renal microvascular thrombosis.Ancillary work interventional randomized open label controlled experimental study. Fifteen female "Large White" pigs (2 months old) were challenged with intravenous infusion E. coli endotoxin. Three groups five animals...
Introduction:The role and incidence of viral infections in respiratory failure occurring ICU patients is more investigated.The availability multiplex PCR assay actually frequently performed.The aim this retrospective study was to assess presence species using a adult admitted for during the November-April period.Patients methods: All period were eligible.A sampling performed according patient severity-sputum, tracheal aspiration, or per fibroscopic broncho alveolar lavage (LBA) analyzed...
Selecting patients most likely to benefit from venoarterial extracorporeal membrane oxygenation (V-A ECMO) treat refractory drug-induced cardiovascular shock remains a difficult challenge for physicians. This study reported short-term survival outcomes and factors associated with mortality in V-A ECMO-treated poisoning. Twenty-two placed on ECMO after drug intoxication January 2014 December 2020 were retrospectively analyzed. The primary endpoint of this was at hospital discharge. Univariate...
Although rare, pseudomembranous colitis may be a cause of perineal necrotising fasciitis in context immunosuppression, as the case we report. This origin must quickly identified because therapeutic management, especially surgery, is unlikely to same usual. Similarly, antibiotic treatment also matter discussion due potential deleterious role antibiotics colitis.
Introduction: Inflating endotracheal tube cuffs using water instead of air before hyperbaric oxygen treatment (HBOT) is common. The objective this study was to assess cuff pressure (Pcuff), when the inflated water, in normobaric conditions and during HBOT. Methods: This a prospective, observational taking place centre intensive care unit University Hospital Lille. Every patient who required tracheal intubation HBOT at 253.3 kPa (2.5 atmospheres absolute [atm abs]) included. Pcuff measured...
Ventilator-acquired pneumonia (VAP) is the leading cause of serious associated infections in Intensive Care Units (ICU) and with significant morbidity. The use hyperbaric oxygen therapy (HBOT) patients on mechanical ventilation may increase exposure to certain risk factors such as hyperoxemia need for multiple transfers. aim our study was assess relationship between HBOT VAP.This retrospective observational performed from March 2017 2018 a 10-bed ICU using HBOT. All receiving (MV) more than...