A5061574130- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Clostridium difficile and Clostridium perfringens research
- Gut microbiota and health
- SARS-CoV-2 and COVID-19 Research
- HIV Research and Treatment
- Infective Endocarditis Diagnosis and Management
- Bacterial Identification and Susceptibility Testing
- Syphilis Diagnosis and Treatment
- Mosquito-borne diseases and control
- HIV/AIDS Research and Interventions
- Virology and Viral Diseases
- Reproductive tract infections research
- Gastrointestinal motility and disorders
- Vector-borne infectious diseases
- Respiratory Support and Mechanisms
- Sepsis Diagnosis and Treatment
- Rabies epidemiology and control
- HIV, Drug Use, Sexual Risk
- Malaria Research and Control
- Pneumonia and Respiratory Infections
- Bacterial Infections and Vaccines
- Dermatological diseases and infestations
- Hepatitis Viruses Studies and Epidemiology
- Orthopedic Infections and Treatments
Méditerranée Infection Foundation
2017-2022
Assistance Publique Hôpitaux de Marseille
2013-2022
Institut de Recherche pour le Développement
2017-2021
Aix-Marseille Université
2017-2021
Hôpital Nord
2021
National Institute for Public Health and the Environment
2020
Biomedical Research Institute
2020
Inserm
2017
Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes
2017
Centre National de la Recherche Scientifique
2017
In our institute in Marseille, France, we initiated early and massive screening for coronavirus disease 2019 (COVID-19). Hospitalization treatment with hydroxychloroquine azithromycin (HCQ-AZ) was proposed the positive cases.
ObjectivesDescribe and evaluate the outcome of a coronavirus disease-2019 (COVID-19) patient without shortness breath.Design methodsWe retrospectively collected data from COVID-19 patients diagnosed cared for in Marseille, France. We selected who at admission, had low dose CT scanner, dyspnea status, oxygen saturation available. Blood gas was analyzed sample subset patients.ResultsAmong 1712 with COVID-19, we report that 1107 (64.7%) do not complain breath admission. The low-dose computed...
Recently, cocktail of bacteria were proposed in order to treat Clostridium difficile infection (CDI), but these bacteriotherapies selected more by chance than experimentation. We propose comprehensively explore the gut microbiota patients with CDI compared healthy donors a consortium for treating C. difficile. stool samples composition from 11 and 8 using two techniques: metagenomics, 16S V3-V4 region amplification sequencing culturomics, high throughout culture six conditions MALDI-TOF...
We evaluated the age-specific mortality of unselected adult outpatients infected with SARS-CoV-2 treated early in a dedicated COVID-19 day hospital and we assessed whether use hydroxychloroquine (HCQ) + azithromycin (AZ) was associated improved survival this cohort. A retrospective monocentric cohort study conducted our center from March to December 2020 adults PCR-proven infection who were as standardized protocol. The primary endpoint 6-week mortality, secondary endpoints transfer...
As a result of Next Generation Sequencing methods, metagenomic studies have become increasingly widespread. After being first applied to microbiome description, metagenomics is currently proposed as diagnostic tool in clinical microbiology, although this application remains confined the field research. In review, we will discuss detection bacterial pathogens and demonstrate that interpretation results may fluctuate depending on type sample analyzed. However, propose view evaluation...
Abstract Objectives To analyse the occurrence of virological failure (VF) in patients starting ART with an integrase strand transfer inhibitor (INSTI)-based regimen recent years, relation previous episodes low-level viral load (LLVL). Patients and methods a first between 1 January 2015 31 December 2020 based on two NRTIs one INSTI were included if after control (two measures VL < 50 copies/mL) they had minimum additional measurements. Cox models adjusted for sex, age, acquisition...
Abstract We investigated a case of dengue virus type 1 infection acquired in Benin. Phylogenetic analysis revealed the strain belongs to genotype V but clusters with Asian, rather than known African, strains. Our finding suggests introduction Asian West Africa.
ObjectivesIn a conventional hospital ward, we used high-flow nasal oxygen (HFNO) to treat elderly COVID-19 patients noneligible for intensive care unit transfer.MethodsThis study was conducted in the Institut Hospitalo-Universitaire Méditerranée Infection, Assistance Publique-Hôpitaux de Marseille (AP-HM), France. We our infectious disease ward from 15 September 2020 transfer.ResultsOf 44 (median age 83 years (57–94), mean: 80.25), 61.4% (27/44) were men. The median Charlson score 7 (1–15)....
Dirofilariasis is one of the oldest known zoonotic infections humans mainly caused by filarial parasites species Dirofilaria immitis and repens, which primarily infect dogs. A five-year survey (2017 to 2021) was conducted among dog population assess molecular prevalence spp. in southeast France. Morphological genetic analysis were performed on filaroids from dogs infected woman studied area. total 12 (13%) scored molecularly positive for nine carried blood microfilariae. Ocular...
Coxiella-like bacteria have been recently proposed as human pathogens. Using molecular techniques, we detected in the blood and serum samples of a patient with scalp eschar, neck lymphadenopathy, severe urticaria, edema, fever, arthralgia indicating that this organism can provide systemic complications.
A case of proven Coxiella burnetii aortitis, possibly associated with giant cell arteritis (GCA), is reported. 72-year-old man, who a hunter, presented weight loss, fever, jaw claudication, and hardened temporal arteries persistent inflammatory syndrome the whole aorta, including brachiocephalic arteries, as seen on 18F-fluorodeoxyglucose positron emission tomography/computed tomography. The diagnosis GCA was retained, treatment prednisolone started. Given aneurysm abdominal patient...
Patients colonized with antibiotic resistant bacteria are at risk of infections and spontaneous decolonization delays highly variable between patients. The management these patients is therefore time-consuming; requires patient isolation, cohort policies. Fecal microbiota transplantation (FMT) has been used the aim shortening this gut colonization. Here, we proposed a comprehensive literature review on FMT utilization for antibiotics decolonization. After research through Pubmed indexed...
SARS-CoV-2 nasopharyngeal shedding contributes to the spread of COVID-19 epidemic. Among 3271 patients treated at Hospital University Institute Méditerranée Infection, Marseille, France from 3 March 27 April 2020, tested least twice by qRT-PCR, median duration was 6 days (range 2-54 days). Compared with short shedders (qRT-PCR positivity < 10 days), 34 (1.04%) persistent ≥ 17 days; mean ± SD: 23.3 3.8 days) were significantly older, associated comorbidities, exhibiting lymphopenia,...
Capnocytophaga sputigena is an unusual cause of community-acquired pneumonia. A 22-year-old woman presented amoxicillin-resistant Sputum examination detected C. from 3 specimens with a significant bacterial load. The strain produced beta lactamase. Evolution was favorable after introduction amoxicillin-clavulanate acid. Physicians might be aware the presence this bacterium in cases
Aspirational targets to end AIDS by 2030 include having 95% of people with human immunodeficiency virus (HIV; PWH) diagnosed, treated, and controlled viral load (VL). Our objective was describe, using a large French prospective cohort, the median transition times through cascade care between 2009 2019. We analyzed patients whose first HIV diagnosis made 1 January 31 December Using Kaplan-Meier method, we estimated time linkage (from biological assessment), treatment (date antiretroviral...