A5088069106- Maternal and Perinatal Health Interventions
- Maternal and fetal healthcare
- Pregnancy-related medical research
- Pregnancy and preeclampsia studies
- Cardiovascular Issues in Pregnancy
- Blood transfusion and management
- Ectopic Pregnancy Diagnosis and Management
- Assisted Reproductive Technology and Twin Pregnancy
- Neonatal Respiratory Health Research
- Pregnancy and Medication Impact
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Inflammasome and immune disorders
- Omental and Epiploic Conditions
- Fetal and Pediatric Neurological Disorders
- Pelvic floor disorders treatments
- Prenatal Screening and Diagnostics
- Reproductive Health and Contraception
- Esophageal and GI Pathology
- Nursing Roles and Practices
- COVID-19 Impact on Reproduction
- Systemic Lupus Erythematosus Research
- Venous Thromboembolism Diagnosis and Management
- Pediatric Hepatobiliary Diseases and Treatments
- Ureteral procedures and complications
- Renal Diseases and Glomerulopathies
Hôpital Pellegrin
2016-2024
Université de Bordeaux
2017-2023
Centre Hospitalier Universitaire de Bordeaux
2016-2023
Centre National de la Recherche Scientifique
2023
Community Link
2022
Université d'Angers
2022
French Clinical Research Infrastructure Network
2021
Bordeaux Population Health
2018
John Wiley & Sons (United Kingdom)
2018
Hudson Institute
2018
Prophylactic administration of tranexamic acid has been associated with reduced postpartum blood loss after cesarean delivery in several small trials, but evidence its benefit this clinical context remains inconclusive.
SARS-CoV-2 positive pregnant women are at higher risk of adverse outcomes, but little evidence is available on how variants impact that risk. We aim to evaluate maternal and perinatal outcomes among unvaccinated tested for SARS-CoV-2, stratified by pre-Delta, Delta, Omicron periods.This prospective study enrolled from March 2020 September 2022. Exposure the different was defined their periods predominance. The primary outcome severe as either intensive care unit admission, acute respiratory...
Chronic histiocytic intervillositis of unknown origin (CHI) is a rare placental disorder associated with adverse pregnancy outcomes, frequent recurrence, and lack effective preventive strategies. Recent insights indicate potential link between CHI-associated inflammatory lesions the inflammasome pathway, suggesting innovative therapeutic avenues. Here we show role pathway in CHI through comprehensive transcriptomic analysis grade 2 or 3 histopathologic samples, paired controls. Additionally,...
Abstract Our study aimed to assess perinatal outcomes and recurrence rate of Chronic Intervillositis Unknown Etiology (CIUE). We conducted an observational retrospective in a tertiary care university hospital France from January 1, 1997 July 31, 2018. 122 pregnancies (102 women) with CIUE were included. Cases the Department Histopathology placenta database re-analysed independently by three pathologists specializing fetal pathology. Diagnosis was confirmed according to: (1) presence cellular...
Chronic intervillositis of unknown etiology (CIUE) is a rare placental disease characterized by intervillous infiltration maternal macrophages and associated with poor pregnancy outcomes high risk recurrence in subsequent pregnancies. Its pathophysiology remains unclear prognostic factors have not yet been established. In addition, clear relationships between the histologic extent lesions severity perinatal demonstrated. Our objectives were to validate CIUE classification system based on...
( N Engl J Med . 2021;384:1623–1634. doi: 10.1056/NEJMoa2028788. PMID: 33913639) As postpartum hemorrhage (PPH) is a common and potentially deadly complication worldwide, mitigating reducing the risk of PPH critical. Tranexamic acid (TXA) has recently been given to reduce blood loss as it reduces breakdown clots in body slows bleeding, decreasing adverse outcomes mortality hemorrhaging women. Smaller studies have suggested that prophylactic administration TXA following cesarean delivery,...
Abstract Objective The aim of this study is to evaluate the diagnostic utility prenatal diagnosis using chromosomal microarray analysis (CMA) for fetuses presenting with isolated or associated intrauterine growth restriction (IUGR). Method We retrospectively included all IUGR referred testing and studied by rapid fluorescence in situ hybridization (FISH), karyotype, CMA. Results Among 162 (78 84 IUGR) included, 15 had an abnormal FISH result: 10 five fetal IUGRs. 143 CMA, (7%) presented...
Our aim was to identify factors associated with shoulder dystocia following an attempted operative vaginal delivery (aOVD) in a prospective cohort study and evaluate whether these can be used accurately predict by building score of risk. This planned secondary analysis deliveries aOVD at term from 2008-2013. Cases were defined as women that requires additional obstetric maneuvers failure gentle downward traction on the fetal head effect shoulders. Multivariate logistic regression analyses...
Objective To define for women at low obstetric risk methods of management that respect the rhythm and spontaneous course giving birth as well each woman's preferences.Methods These clinical practice guidelines were developed through professional consensus based on an analysis literature French international available this topic.Results Labor should be monitored with a partograph (professional consensus). Digital cervical examination offered every 4 h during first stage labor, hourly second....
To assess severe short-term maternal and neonatal morbidity pelvic floor disorders at 6 months postpartum after attempted operative vaginal delivery according to the instrument used.We conducted a prospective study of women with live, singleton, term fetuses in vertex presentation. Patients French tertiary care university hospital from December 2008 through October 2013. We used multivariable logistic regression propensity score methods control for indication bias compare outcomes associated...