A5101060478- HIV-related health complications and treatments
- Reconstructive Surgery and Microvascular Techniques
- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Food Security and Health in Diverse Populations
- Electrospun Nanofibers in Biomedical Applications
- Child Nutrition and Feeding Issues
- Bone fractures and treatments
- Periodontal Regeneration and Treatments
- Reconstructive Facial Surgery Techniques
- Bone Metabolism and Diseases
- Nutritional Studies and Diet
- Tissue Engineering and Regenerative Medicine
- Wound Healing and Treatments
- Folate and B Vitamins Research
- Medical and Biological Ozone Research
- Tendon Structure and Treatment
- Orthopedic Surgery and Rehabilitation
- HIV Research and Treatment
- Diet and metabolism studies
- HIV, Drug Use, Sexual Risk
- Hydrogels: synthesis, properties, applications
- COVID-19 Impact on Reproduction
- Organ and Tissue Transplantation Research
- Connective Tissue Growth Factor Research
Florida International University
2019-2025
Guangdong Provincial People's Hospital
2010-2024
General Hospital of Guangzhou Military Command
2013-2018
Southern Medical University
2014-2015
Background: As the first line of immune defense and largest organ body, skin is vulnerable to damage caused by surgery, burns, collisions other factors. Wound healing in a long complex physiological process that influenced number different Proper wound care can greatly improve speed reduce generation scars. However, traditional dressings (bandages, gauze, etc.) often used clinical practice have single function, lack active ingredients are limited use. Hydrogels with three-dimensional network...
Wound healing has been a great challenge throughout human history. Improper treatment for wounds is so easy to lead infection and series of serious symptoms, even death. Because the ability absorbing fluid keeping moist environment, hydrogel with 3D networks ideal candidate wound dressing. More important, it good biocompatibility. However, most dressings reported have weak mechanical properties adhesion properties, which greatly limit their clinical application. Herein, tough adhesive...
Background: Understanding immune response is essential for preparing public health crises. COVID-19 vaccination provides robust immunity against SARS-CoV-2, but immunocompromised populations may have weaker responses. We assessed SARS-CoV-2 spike (trimer) total IgG/IgM/IgA (total Ig) to investigate in people living with HIV (PLWH), considering CD4+ T cell count, viral load, substance use, and comorbidities. Methods: This cross-sectional study was conducted Miami, Florida, between May 2021...
Activation of transforming growth factor-β (TGF-β) signaling and matrix metalloproteinases are involved in hypertrophic scar (HS) formation. Compression therapy is known to be an effective approach for the treatment scarring; however, underlying molecular mechanisms remain poorly understood. We investigated relationship between TGF-β activation HS fibroblasts during mechanical compressive stress.Two groups skin tissue from nearby normal were obtained surgical patients analyzed. Primary...
Major ozonated autohemotherapy is classically used in treating ischemic disorder of the lower limbs. In present study, we performed major treatment patients with acute cerebral infarction, and assessed outcomes according to U.S. National Institutes Health Stroke Score, Modified Rankin Scale, transcranial magnetic stimulation motor-evoked potential. Compared control group, clinical total effective rate cortical potential rise upper limbs were significantly higher, central motor conduction...
Background: HIV infection disproportionally affects African Americans. Liver disease is a major cause of non-HIV morbidity and mortality in this population. Substance abuse accelerates may facilitate progression liver disease. This study investigated the relationship between sex differences cocaine use with injury, characterized as hepatic fibrosis. Materials Methods: A cross-sectional was conducted on 544 Americans [369 people living (PLWH) 175 seronegative] from Miami Adult Studies (MASH)...
Sensory function is the most significant criterion when evaluating prognosis of replanted fingers. Current clinical research has focused on surgical techniques and indications for finger replantation; however, few studies have recovery sensory after replantation. This study retrospectively assessed data eight patients who had undergone nine Zone I replantations fingertips in First Affiliated Hospital Sun Yat-sen University China from July 2014 to January 2016. Variations extent damage, with...
Abstract The reconstruction of finger defects requires improved functional outcomes and acceptable esthetic outcomes, small free flaps present a good alternative technique for repairing skin defects. From January 2006 to December 2018, we investigated the number diameter proximal digital artery perforators, medial plantar peroneal proper arteries hallux by dissection then transplanted arterial perforator flaps, from repair (SD) perforators was approximately 2.2 (0.5), these measured 0.53...
BACKGROUND Osteoclast formation is closely related to the immune system. FTY720, a new immunosuppressive agent, has some functions in regulation. Its main active ingredients become FTY-720P vivo by phosphorylation modification. The objective of this study was determine effects FTY-720 with various concentrations on osteoclasts vitro. MATERIAL AND METHODS RAW264.7 cells and bone marrow-derived mononuclear phagocytes (BMMs) were treated RANKL obtain To investigate role osteoclast formation,...
Abstract Persistent immune activation is a hallmark of human immunodeficiency virus (HIV) infection and thought to play role on chronic diseases in people with HIV (PWH). Food insecurity disproportionately prevalent PWH associated adverse health outcomes. We determined whether food was increased plasma levels soluble CD14, CD27, CD163 323 antiretroviral-treated from the Miami Adult Studies cohort. Nearly half (42.7%) participants were insecure, 85.5% virally suppressed (<200...
Cannabis is the most prevalently used substance in United States and among people living with HIV (PLWH). Underserved minorities suffer from high rates of obesity. Yet, little known about implications cannabis use on body composition PLWH. Thus, we sought to determine association between In this cross-sectional study, participants were selected ongoing Miami Adult Studies (MASH) cohort. was self-reported confirmed urinalysis for along other illicit drugs (American Bio Medica Corp,...
Food insecurity affects underserved and marginalized populations in the United States, which could lead to a decline quality of life over time further worsening health outcomes. This study aims determine association between food security among people living with without HIV Miami, FL. was cross-sectional analysis minority population from Miami Adult Studies on (MASH) cohort. Demographics, anthropometrics, fasting blood samples were collected by trained personnel. viral loads (VL, copies/ml)...
ObjectivesImmune activation is central to developing insulin resistance and implicated in the pathophysiology of liver steatosis. People living with HIV (PLWH) have elevated biomarkers immune activation, which may play a role faster development The objective this study was examine if status are related
To investigate the effectiveness of anterolateral femoral flap in combination with fascia lata grafting repair large Achilles tendon and skin defects.The clinical data 18 patients defects repaired between January 2018 2019 were retrospectively reviewed. There 14 males 4 females; age ranged from 32 to 57 years (mean, 42.1 years). 9 cases postoperative infection rupture, 1 case traffic accident injury, 8 combined after heel trauma. The length defect was 4-8 cm, an average 5.6 cm; range cm×3 cm...
Cardiovascular disease (CVD) and liver risks are higher in people living with HIV (PLWH) than the general population. We evaluated association between Framingham Heart Study (FHS) 10-year CVD risk noninvasive indicators PLWH compared seronegative individuals. Cross-sectional study included adults from MASH cohort. Demographics, anthropometrics, drug/cigarette use, blood samples (metabolic panel) were collected by trained personnel. status was obtained medical records informed consent....
Objective To analyze the effectiveness of DirectPath in reconstructing threedimensional bronchial tree based on different slice thickness computed tomography images and evaluate ability guiding a conventional bronchoscope or an ultrathin to target peripheral bronchus. Methods 60 patients with solitary pulmonary nodules discovered by chest scan were selected. Computed was performed 8-row 64-row multidetector. CT 30 multidetector group recorded 1.25 mm slices, 0.625 slices respectively....
Objective To investigate the application valve of bFGF to improve viability trans-plantation flap in Wistar rat. Methods Forty-eight rats were randomly divided into two groups based on age: group A,B(1.5 month old, every was 12 rats) and C,D (3 rats). After an ischemic model completed, recombinant bovine basic fibroblast growth factor (rb-bFGF) given A C ischemie zone by vascularization injection equality normal saline B D. 14 days postoperatively, muscular tissue sent for histology, blood...