A5061215014- Pharmaceutical and Antibiotic Environmental Impacts
- Environmental Toxicology and Ecotoxicology
- Toxic Organic Pollutants Impact
- Marine Biology and Ecology Research
- Water Quality and Pollution Assessment
- Pesticide and Herbicide Environmental Studies
- Analytical chemistry methods development
- Metabolomics and Mass Spectrometry Studies
- Marine and coastal plant biology
- Effects and risks of endocrine disrupting chemicals
- Water Quality Monitoring and Analysis
- Marine Bivalve and Aquaculture Studies
- Marine and fisheries research
- Coral and Marine Ecosystems Studies
- Computational Drug Discovery Methods
- Turtle Biology and Conservation
- Water Treatment and Disinfection
- Gut microbiota and health
- Pneumocystis jirovecii pneumonia detection and treatment
- Wastewater Treatment and Reuse
- Bacterial Infections and Vaccines
- Heavy metals in environment
- Aquaculture disease management and microbiota
- Mosquito-borne diseases and control
- Cytomegalovirus and herpesvirus research
University of Gothenburg
2018-2024
Curtin University
2020-2023
Australian Red Cross Lifeblood
2007
The textile industry, while of major importance in the world economy, is a toxic industry utilizing and emitting thousands chemical substances into aquatic environment. aim this project was to study potentially harmful effects associated with leaching residues from three different types textiles: sportswear, children’s bath towels, denim using fish models (cell lines, larvae juvenile fish). A combination vitro vivo test systems used. Numerous biomarkers, ranging gene expression, cytotoxicity...
Reducing the risk posed by mixtures of pharmaceuticals is a goal current initiatives such as European Green Deal to reduce anthropological environmental impacts. Wastewater effluent typically contains large numbers active pharmaceutical ingredients (APIs). For some APIs, existing technology conventional activated sludge (CAS) wastewater treatment plants (WWTPs) have removal rates below 20 %, thus WWTP discharges are adding toxic burden receiving waters. We present an assessment 35 APIs in...
Rivers discharging to the Great Barrier Reef carry complex pesticide mixtures. Here we present a first comprehensive ecotoxicological risk assessment using species sensitivity distributions (SSDs), explore how changes with time and land use, identify drivers of mixture risks. The analyzed data set comprises 50 different pesticides metabolites that were in 3741 samples from 18 river creek catchments between 2011 2016. Pesticide mixtures 82% samples, maximum 23 median five compounds per...
The gut microbiome of fish contains core taxa whose relative abundances are modulated in response to diet, environmental factors, and exposure toxicogenic chemicals, influencing the health host fish. Recent advances genomics metabolomics have suggested potential analysis as a biomarker for compounds. In this 35-day laboratory study, 16S RNA sequencing multivariate were used explore changes juvenile Lates calcarifer exposed dietary sub-lethal doses three metals: vanadium (20 mg/kg), nickel...
ADVERTISEMENT RETURN TO ARTICLES ASAPPREVViewpointNEXTEnhanced Risk Assessment of Transformation Products through Chemical Similarity AnalysisPaul Löffler*Paul LöfflerDepartment Aquatic Sciences and Assessment, Swedish University Agricultural (SLU), Uppsala SE-75007, Sweden*[email protected]More by Paul LöfflerView Biographyhttps://orcid.org/0000-0003-1959-0752, Adelene LaiAdelene LaiWater Information from Earth Observation (WEO), Luxembourg City L-1911, LuxembourgMore...
Empirical and in silico data on the aquatic ecotoxicology of 2697 organic chemicals were collected order to compile a dataset for assessing predictive power current Quantitative Structure Activity Relationship (QSAR) models software platforms. This document presents pipeline its creation. from US EPA ECOTOX Knowledgebase (ECOTOX) EFSA (European Food Safety Authority) report "Completion entry pesticide Tier 1 study endpoints XML schema – database". Only algae, daphnia fish retained. Data...
Innate immune system deficiency may predispose to severe infections such as Legionnaires' disease. We have investigated the role of mannose-binding lectin (MBL) in Melbourne Aquarium disease outbreak. Serum samples from patients and controls that were exposed but shown be uninfected outbreak tested for MBL function (C4 deposition) level (mannan-binding). was lower cases than age- sex-matched uninfected, controls. The frequency with C4 deposition < 0.2 U/microl significantly higher This also...
Introduction The west coast of Western Australia (WA) is a global hotspot for increasing sea surface temperatures and marine heatwaves. Methods We used visual survey transects to compare mollusc echinoderm populations on three coastal intertidal platform reefs the Perth shoreline with two platforms at end Rottnest Island (32°S) which are under influence southward flowing Leeuwin Current. Results In 1983, temperate species dominated molluscan diversity, but tropical mussel Brachidontes...
Urban wildlife often suffer poorer health than their counterparts living in more pristine environments due to exposure anthropogenic stressors such as habitat degradation and environmental contamination. As a result, the of urban versus nonurban snakes might be assessed by differences plasma biochemistries. We compared profiles western tiger (Notechis scutatus occidentalis) from heavily urbanized wetland natural, nonurbanized wetland. Despite having lower body mass index, we found no...
Abstract Active pharmaceutical ingredients (APIs) and their transformation products inevitably enter waterways where they might cause adverse effects to aquatic organisms. Identifying the potential risks of APIs in environment is therefore a goal current strategic direction environmental management described EU Strategic Approach Pharmaceuticals Environment Green Deal. This challenged by paucity monitoring ecotoxicity data adequately describe risks. In this study we analyze measured...
Few data sets are available to evaluate short- and long-term perturbations impacts of increasing anthropogenic stresses a warming marine environment in coastal regions near cities. The Perth, Western Australia shoreline has extensive, depauperate sandy beaches interrupted by small, biodiverse intertidal reef platforms. We present transect on mollusc diversity density three Perth platforms recorded from 1983 1987, compare it 2007 2021 analyse assemblage modifications response increased...
Context Eutrophication caused extensive macroalgal blooms in the Peel–Harvey Estuary, Western Australia, 1970s. Nutrient inputs were reduced and an artificial channel was constructed 1994 to increase marine flushing. Aims This study examines benthic mollusc populations estuary 1978, 2000 2020, determine what changes have occurred estuaries over time. Methods Quantitative samples made at 10 sites autumn spring of each year; physical chemical parameters measured 2020. Key results Species...
The Great Barrier Reef (GBR) is a protected ecosystem, listed as UNESCO World Heritage site since 1981. It runs for approximately 3000km along the coastline in north-eastern Australia. A total of thirty-five major river basins discharge to GBR and many transport large loads pesticides, suspended sediment, nutrients from agricultural land. Over past 6 years an extensive program has been conducted by Queensland Government monitor concentrations 51 pesticides their breakdown products 17 rivers...
The Great Barrier Reef (GBR) is a protected ecosystem, listed as UNESCO World Heritage site since 1981. It runs for approximately 3000km along the coastline in north-eastern Australia. A total of thirty-five major river basins discharge to GBR and many transport large loads pesticides, suspended sediment, nutrients from agricultural land. Over past 6 years an extensive program has been conducted by Queensland Government monitor concentrations 51 pesticides their breakdown products 17 rivers...
In the present study, we investigated possibility of identifying source oils exposed fish using ratios bicyclic sesquiterpane (bicyclane) chemical biomarkers. event an oil spill, identification oil(s) for assessment, or litigation purposes, typically uses diagnostic biomarkers to produce characteristic "fingerprints." Although this has been applied in residues sediments, water, and sessile filtering organisms, so far as are aware never successfully demonstrated oil-exposed fish. a 35-day...
Reducing the risk posed by mixtures of pharmaceuticals is a goal current initiatives such as European Green Deal to reduce anthropological environmental impacts. Wastewater effluent typically contains large numbers active pharmaceutical ingredients (APIs). For most APIs, existing technology commonly used in many wastewater treatment plants (WWTP) have removal rates below 20%, adding toxic burden receiving waters.We present an assessment 35 APIs samples from 82 WWTPs using concentration...
Identifying the sources of environmental oil contamination can be challenging, especially for in motile organisms such as fish. Lipophilic hydrocarbons from bioaccumulate fish adipose tissue and potentially provide a forensic "fingerprint" original oil. Herein, diamondoid hydrocarbon distributions were employed to fingerprints. Indices produced diamondoids used compare extracts tissues crude fuel oils which exposed under laboratory conditions. A suite 20 was found have bioaccumulated...