- Biochemical effects in animals
- Liver Disease Diagnosis and Treatment
- Antioxidant Activity and Oxidative Stress
- Aldose Reductase and Taurine
- Alcohol Consumption and Health Effects
- Free Radicals and Antioxidants
- Diet, Metabolism, and Disease
- Vitamin C and Antioxidants Research
- Fatty Acid Research and Health
- Drug-Induced Hepatotoxicity and Protection
- Folate and B Vitamins Research
- Eicosanoids and Hypertension Pharmacology
- Adipose Tissue and Metabolism
- Sulfur Compounds in Biology
- Liver Disease and Transplantation
- Heme Oxygenase-1 and Carbon Monoxide
- Biochemical Acid Research Studies
- Advanced Glycation End Products research
- Thyroid Disorders and Treatments
- DNA Repair Mechanisms
- Genomics, phytochemicals, and oxidative stress
- Birth, Development, and Health
- Atherosclerosis and Cardiovascular Diseases
- Healthcare and Venom Research
- Diet and metabolism studies
Istanbul University
2013-2024
Bakırköy Psychiatric Hospital
2023
Yeditepe University
2017
Bakırköy Dr.Sadi Konuk Eğitim ve Araştırma Hastanesi
2017
Plovdiv University
2014
University of Nis
2014
Konkuk University
2014
Ain Shams University
2014
Near East University
2007
Balikli Rum Vakfi Hastanesi
2000
Thioacetamide (TAA) administration (0.3 g/l of tap water for a period 3 months) to rats resulted in hepatic cirrhosis as assessed by biochemical and histopathological findings. This treatment caused an increase the levels malondialdehyde (MDA) diene conjugates (DCs) decrease glutathione (GSH), vitamin E, C activities peroxidase (GSH-Px) liver rats. Superoxide dismutase (SOD) were unchanged. Taurine (2% w/w, added chow diet) was administered together with TAA drinking water) months. found...
Lipid peroxidation and the antioxidant system were investigated in plasma placenta of normal preeclamptic pregnant women. A significant increase thiobarbituric acid reactive substance (TBARS), decreases total thiol (t-SH) content superoxide dismutase (SOD) activity, unchanged vitamin C levels glutathione peroxidase (GPx) activity observed women compared to with pregnancies. In placentas from TBARS significantly elevated, while GPx, S-transferase SOD activities decreased. After delivery,...
Doxorubicin (DOX) is known to increase in oxidative stress several organs. Olive leaf extract (OLE) has potent antioxidant effects; therefore, we evaluated the ability of OLE reduce DOX-induced toxicity heart, liver, and kidneys rats. DOX (30mg/kg; i.p.) was administered rats, which were sacrificed 4 days after DOX. The rats received (6 12mL/L drinking water) for 12 days. Serum cardiac troponin I (cTnI) levels, alanine aminotransferase (ALT), aspartate (AST) activities, urea creatinine as...
The effect of a high-cholesterol diet with or without taurine on lipids and oxidative stress in the plasma, liver aorta rabbits was investigated. animals were maintained basal (control), (HC, 1% w/w), high- cholesterol supplemented (HCHT, 2.5% w/w) for two months. Taurine has an ameliorating atherosclerosis together decreasing triglyceride levels fed HC diet. HCHT caused significant decrease malondialdehyde (MDA) diene conjugate (DC) as compared to group. This treatment did not alter...
Summary Ulcerative colitis (UC) is a multi-factorial inflammatory disease of the colon and rectum. The present study was undertaken to investigate effect taurine, an anti-oxidant amino acid, on oxidative stress expression apoptosis-related proteins, pro-apoptotic Bax anti-apoptotic B cell lymphoma-2 (Bcl-2) in tissue rats with 2,4,6-trinitrobenzene sulphonic acid (TNBS)-induced colitis. Rats received taurine (1·5% w/v) drinking water for 15 days before after administration TNBS solution....
Aim Olive leaf (Olea europaea L.) extract (OLE) is a powerful anti-oxidant rich in polyphenols. As oxidative stress plays an important role aging, we investigated the effect of OLE on liver, heart and brain aged rats. Methods Young (age 3 months) 20 Wistar rats were used. Aged received (500 1000 mg/kg/day) drinking water for 2 months. Malondialdehyde (MDA), diene conjugate (DC), protein carbonyl (PC), glutathione (GSH), vitamin E C levels, superoxide dismutase (SOD), peroxidase (GSH-Px)...
Summary High‐fat diet ( HFD ) and low‐dose streptozotocin STZ )‐treated rats provide useful animal model for type II diabetes mellitus. Oxidative stress advanced glycation end products AGE s) play a role in the development of diabetic complications. Carnosine CAR has anti‐oxidant anti‐glycating properties. We investigated effects on oxidation + rats. Rats were fed with (60% total calories from fat) 4 weeks, then single dose (40 mg/kg; i.p.) was applied. blood glucose levels above 200 mg/ dl...
In this study, we evaluated whether taurine treatment has a protective effect on the prooxidant-antioxidant state following chronic ethanol in rats. Rats were given water containing 20% (v/v) as drinking for 3 months. Chronic resulted increased oxidative stress liver of Taurine was performed by adding 1% (w/v) to plus injection (400 mg/kg body weight) intraperitoneally times/week 28 d after cessation chronically ethanol-treatad This starting caused significant decreases serum transaminase...