- Microbial infections and disease research
- Pancreatitis Pathology and Treatment
- Veterinary Oncology Research
- Animal Virus Infections Studies
- Curcumin's Biomedical Applications
- Vector-Borne Animal Diseases
- Veterinary Medicine and Surgery
- Prion Diseases and Protein Misfolding
- Neurological diseases and metabolism
- Virus-based gene therapy research
- Thyroid Cancer Diagnosis and Treatment
- Liver Disease Diagnosis and Treatment
- Neurological Disease Mechanisms and Treatments
- Testicular diseases and treatments
- Ovarian cancer diagnosis and treatment
- Herpesvirus Infections and Treatments
- Effects of Environmental Stressors on Livestock
- Biochemical effects in animals
- Veterinary Orthopedics and Neurology
- Pancreatic and Hepatic Oncology Research
- Metallurgy and Material Science
- Therapeutic Uses of Natural Elements
- Medical and Biological Ozone Research
- Parasite Biology and Host Interactions
- Veterinary Pharmacology and Anesthesia
Istanbul University-Cerrahpaşa
2019-2025
Istanbul University
2005-2022
GTx (United States)
2006
Summary Inflammatory cytokines have been demonstrated to play an important role in the induction and severity of acute pancreatitis (AP) recent studies. The aim this study was investigate effects curcumin on inflammatory cytokines, such as tumour necrosis factor (TNF)‐ α interleukin (IL)‐6 late phase AP. conducted 40 male Wistar Albino rats. animals were divided randomly into four equal groups. AP induced by infusion 3% sodium taurocholate biliopancreatic duct (in groups I II). Starting day...
To investigate the effects of long term pretreatment with low-, medium- and high-dose aspirin (acetylsalicylic acid, ASA) on a model acute pancreatitis (AP) induced in rats.Forty male Wistar rats were used. Three experimental groups, each consisting eight animals, received low- (5 mg/kg per day), (150 day) (350 ASA supplemented pellet chow for 100 d. Eight serving as AP-control group, another eight, reference value (RV) fed standard same period. After pretreatment, AP was animals by...
To investigate the neuroprotective effect of chronic curcumin supplementation on rat forebrain prior to ischemia and reperfusion.Forebrain was induced by bilateral common carotid artery occlusion for 1/2 hour, followed reperfusion 72 hours. Older rats were divided into five groups: Group I received 300 mg/kg oral 21 days before intraperitoneal after ischemia; II III IV had only V sham-operated group. The rapidly dissected biochemical parameter assessment histopathological examination.In...
The aim of study was to evaluate a case granulomatous conjunctivitis, clinically and pathologically, in the right eye 2-year-old, female ostrich. A mass measuring 5 cm×3 cm×4 cm removed surgically from Morexella phenylpyruvica recovered mass. On histopathological examination, hyperplasia or squamous metaplasia some area conjunctival palpebra, inflammation submucosa were observed. lesion described as conjunctivitis caused by M. phenylpyruvica. located lower eyelid conjunctiva not only...
A 3-year-old female dog was referred to the clinics of İstanbul University with complaint abdominal distention. On basis clinical findings and ultrasonography, a mass detected in left ovary. An ovariohysterectomy performed. Grossly, mass, dimensions 15 × 11 8 cm, weighed 1.2 kg contained hairs, cysts, fat, bone, cartilage on cut surface. Histology revealed occurrence well-differentiated components all 3 germ layers diagnosed as benign mature cystic teratoma.
Aspergillosis is a fungal infection affecting respiratory system both in mammals and avian species. It more commonly encountered birds, comparison with its mammalian counterpart. Mostly isolated strains are Aspergillus fumigatus (95%) flavus (5%). Affected lungs air sacs reveal miliary to gross lesions like gray-yellowish or white-grayish granulomatous foci surrounded by white halos indicative of inflammatory infiltration. Five storks found dead the rural areas near Istanbul were submitted...
Scrapie is a fatal neurodegenerative disease affecting small ruminants that causes economic losses in many countries. It categorized together with other diseases as transmissible spongiform encephalopathy. The aim of this study was to investigate clinical cases and the cause death flock sheep from Northern Cyprus (Turkish Republic Cyprus) suspected having scrapie. Brains 4 showing signs classical scrapie, out 200 animals, were analyzed by histopathological examination infective prion...
In this report, an ameloblastoma case, which has been occurred on the left maxilla of a 10 year-old, male, German shepherd, was described clinical and morphological features. The mass with dimensions 5 x 2.5 cm removed totally by maxillectomy examined radiography, magnetic resonance (MR) biopsy. tumor histopathologically classified follicular type in some fields showed acanthotic form. invasiveness also observed to be high. This report is first case maxillary dogs Turkey.
Abstract Effects of vitamin E and Se on cancer induced by N-N'itroso-N-Methylurea. which is a chemical carcinogen were investigated in this study. The study was carried out with 50 female Wistar-AIbino rats. animals divided into five groups: Four experimental 1 control (n: 10). groups II daily given 3ppm/lt sodium sclcnit via drinking water starting 45 days prior to NMU injection, while IV injected intraperitoneally (i.p) three times week. At the end 45-day-period blood samples taken from...
An 11-year old, Rottweiler bitch was presented to the clinic with complaint of a huge mass protruding from left side vulvar labium. The had been ovariohysterectomized due pyometra 2 years ago. perivulvar surgically removed by using an electrocautery device under general anesthesia. Macroscopically, pedunculated 20 cm x 25 in diameter, capsulated and slightly firm. Histopathological examination revealed that hemangiosarcoma originating mucosa. Marked anisocytosis anisokaryosis were noted...
Equine herpesvirus-1 (EHV-1) is a cause of pneumonia, encephalitis, and abortion in horses. Abortions occur alive or dead the last trimester pregnancy. The aim this study to investigate incidence EHV-1 infections tissue samples aborted stillborn live-born foals which died soon after birth compare correlate conventional histopathologic diagnosis with IHC Real-Time PCR. For purpose, (lung, liver, spleen, kidney, placenta, brain) 38 from Istanbul, Kocaeli, Bursa, Eskişehir provinces Turkey...
Cystic changes of ovarian tissue are crucial as they cause infertility in laboratory animals. A 4 years old, weighing approximately 500 g adult, intact guinea pig had pruritic progressive alopecia over the flanks at dorsal area and abdomen symmetrically, bilaterally for a month. Beside, an abdominal enlargement was observed outside on pig. Large polycystic ovaries were detected behind kidneys during ultrasonography. Also radiography revealed cystic structures same region. Ovariohysterectomy...
Ozet Bu calismada 1995-2000 yillari arasinda Istanbul Universitesi Veteriner Fakultesi Patoloji Anabilim Dali'nda incelenen degisik irk ve cinsiyete sahip 182 adet kopege ait cesitli doku organlarda saptanan tumorlerin istatistiksel degerlendirilmesi yapildi. Tumor tanisi konulan bu vakalardan %89.01'intn malign, %I0.99'unun benign karakterde oldugu saptandi. Incelenen kopekten 21 tanesinin yasi bilinmemektir. Bunun disinda kalan 161 kopegin %52'si 6-10 yas arasi, %28'i 1-5 %15'i 11-15 %4'u...
In this study we investigated the effects of antibiotic and intraperitoneal ozone administration on pro-inflammatory cytokine, antioxidant levels tissue damage in treatment experimentally infectious peritonitis. Thirty-three adult male New Zealand White Rabbits were used. The consisted four groups including non-treatment group (G1), (G2), (G3) + (G4). Trimethoprim sulfadimethylprymidine was administered at a dose 50 mg/kg subcutaneously (s.c.) amoxicillin sodium 15 intramuscularly (i.m.)....