A5101703570- Asthma and respiratory diseases
- Respiratory and Cough-Related Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Eosinophilic Esophagitis
- Energetic Materials and Combustion
- Magnetic confinement fusion research
- Air Quality and Health Impacts
- Nuclear Physics and Applications
- IL-33, ST2, and ILC Pathways
- Hydrogen's biological and therapeutic effects
- Environmental and Agricultural Sciences
- Higher Education and Teaching Methods
- Cancer-related molecular mechanisms research
- Crystallography and molecular interactions
- Pediatric health and respiratory diseases
- Respiratory Support and Mechanisms
- Medical Research and Treatments
- Ideological and Political Education
- Crystal structures of chemical compounds
- Inflammatory Biomarkers in Disease Prognosis
- Religion, Ecology, and Ethics
- Atomic and Molecular Physics
- Ginseng Biological Effects and Applications
- Chemical Analysis and Environmental Impact
- Cardiac tumors and thrombi
Lanzhou University
2013-2025
First Hospital of Lanzhou University
2013-2025
Peking University Third Hospital
2023
Yulin University
2023
Peking University
2023
Chinese People's Liberation Army
2023
Northwestern Polytechnical University
2022
Sichuan University
2021
Qilu Hospital of Shandong University
2015
Institute of Soil and Water Conservation
2015
Chronic obstructive pulmonary disease (COPD) is a whose incidence increase with age and characterised by chronic inflammation significant immune dysregulation. Inhalation of toxic substances cause oxidative stress in the lung tissue as well airway inflammation, under recruitment chemokines, cells gathered are activated to play defensive role. However, persistent damages system leads dysregulation, which mainly manifested reduction body's response antigens, function impaired, further destroy...
Abstract Three high‐energy multicore ferrocene‐based catalysts containing energy bonds (C═N, N–N) (EMFcs), EMFcs‐1, EMFcs‐2, and EMFcs‐3, were designed synthesized to reduce the high temperature decomposition (HTD) increase heat release of ammonium perchlorate (AP) as well improve anti‐migration performance for development composite solid propellants. The theoretical calculation highest occupied molecular orbital ( E HOMO ), lowest unoccupied LUMO electrostatic potential (ESP) performed...
Abstract Since the last IAEA-FEC in 2021, significant progress on development of long pulse steady state scenario and its related key physics technologies have been achieved, including reproducible 403 s long-pulse steady-state H-mode plasma with pure radio frequency (RF) power heating. A thousand-second time scale (∼1056 s) fully non-inductive high injected energy up to 1.73 GJ has also achieved. The EAST operational regime β P significantly extended ( H 98y2 > 1.3, ∼ 4.0, N 2.4 n e / GW...
To identify the molecular targets and possible mechanisms of isoliquiritigenin (ISO) in affecting chronic obstructive pulmonary disease (COPD) by regulating glycolysis phagocytosis alveolar macrophages (AM). Datasets GSE130928 GSE13896 were downloaded from Gene Expression Omnibus (GEO) database. Genes related to phenotypes obtained GeneCards MSigDB databases, respectively. Weighted gene co-expression network analysis (WGCNA) differential conducted on potential target genes for COPD (gene...
Details of patients hospitalized for asthma exacerbation in mainland China are lacking. To improve disease control and reduce economic burden, a large sample survey among this patient population is indispensable. This study aimed to investigate the clinical characteristics outcomes such patients.A retrospective was conducted on 29 hospitals regions during period 2013 2014. Demographic features, pre-admission conditions, details, were summarized. Risk factors severity analyzed.There 3,240...
Oxidative stress plays an essential role in the pathogenesis of cardiovascular diseases and osteoporosis resulting from oestrogen deficiency postmenopausal period. In this report, we observed a dynamic change oxidative DNA damage after ovariectomy female rats. We then compared phytoestrogen puerarin 17β-oestradiol (E₂) their effects on deficiency-induced damage. Serum total antioxidant capacity (TAC), malondialdehyde (MDA) lymphocytes (comet%) were measured. There was gradual increase...
Four novel energetic ferrocene‐based coordination derivatives, namely [M (FcHz)·(NO 3 )] n (M = Co 2+ , Cu Zn and Fe 3+ ), were successfully prepared through a solvothermal method using 1,1′‐bis(1‐hydrazinoethylene) ferrocene (FcHz) with excellent electron transfer ability energy bonds (C=N, N–N) as ligand to coordinate transition metals high catalytic activity promote the decomposition of ammonium perchlorate (AP). Their chemical structure, crystalline features, morphology comprehensively...
Objectives: To investigate the association of cytotoxic T lymphocyte-associated antigen 4 (CTLA4) with immune thrombocytopenia (ITP).Methods: A case–control analysis 277 Chinese Han children was performed. The tagging variants rs11571315 and rs3087243 in CTLA4 gene were detected using polymerase chain reaction-restriction fragment length polymorphism method. expression quantitative trait loci (eQTL) real-time reaction performed to determine relationship ITP.Results: Neither SNP significantly...
Asthma is associated with a T helper (Th)17/regulatory (Treg) cells immune imbalance where the Notch signaling pathway contributes vitally. This study aimed to explore role of ligands Jagged1 and Delta4 in Th17/Treg chronic asthmatic mice.The experimental animals were randomly assigned Saline, ovalbumin (OVA), OVA + γ-secretase inhibitor (GSI) groups. A mouse model asthma was induced by sensitization challenge. GSI injected intraperitoneally before challenge group. Lung function, lung...
Structural MRI (sMRI) has been widely used to examine the cerebral changes that occur in Parkinson's disease (PD). However, previous studies have aimed for brain at group level rather than individual level. Additionally, inconsistent regarding they identified. It is difficult identify which regions are true biomarkers of PD. To overcome these two issues, we employed four different feature selection methods [ReliefF, graph-theory, recursive elimination (RFE), and stability selection] obtain a...
Studies have shown that eosinophils are closely related to pathogenesis of bronchial asthma. Eosinophils release eosinophil cationic protein (ECP), which plays an important role in infection and allergic reactions. Serum ECP mRNA expression children with asthma has not been adequately investigated. We analyzed serum 63 21 healthy by using reverse-transcriptase polymerase chain reaction understand the The were segregated into acute-phase stable-phase groups, based on severity illness. (0.375...
While asthma comorbidities are associated with higher health care utilisation, lower quality of life and poorer control, the impact on hospitalisation for exacerbation (H-AX) remains less recognised. We aim to analyse H-AX.Based a national survey control disease perception (CARN 2015 study), we analysed annual incidence frequency H-AX in China. Information demographic characteristics, were presented this study.Among 3875 ambulatory patients, 75.9% (2941/3875) had comorbidities, 26.4%...
A metal–organic framework (Ni/Co-DAP MOF) with porous organic polymer DAP as a ligand delivers remarkable performance for energy storage and glucose sensing.