A5055126969- Atherosclerosis and Cardiovascular Diseases
- Adipokines, Inflammation, and Metabolic Diseases
- Diet and metabolism studies
- Alzheimer's disease research and treatments
- Nanoparticle-Based Drug Delivery
- Lipoproteins and Cardiovascular Health
- Computational Drug Discovery Methods
- Galectins and Cancer Biology
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Inflammasome and immune disorders
- Receptor Mechanisms and Signaling
- Peroxisome Proliferator-Activated Receptors
- Nanoplatforms for cancer theranostics
- Natural Compounds in Disease Treatment
- Graphene and Nanomaterials Applications
- Advanced Drug Delivery Systems
- Diabetes and associated disorders
- Advancements in Transdermal Drug Delivery
- Cholinesterase and Neurodegenerative Diseases
- Phytochemical compounds biological activities
- Biological Activity of Diterpenoids and Biflavonoids
- Liver Disease Diagnosis and Treatment
- Coenzyme Q10 studies and effects
- Cancer Research and Treatment
- Nicotinic Acetylcholine Receptors Study
Kerala University of Health Sciences
2022
King Abdulaziz University
2014-2018
The diterpenoid, sugiol, has been reported to exert anticancer effects against a number of human cancers. However, the sugiol have not evaluated glioma cells. present study was designed examine on proliferation U87 results showed that significantly (P < 0.05) suppressed viability cells in concentration dependent manner and exhibited an IC50 value 15 μM. On other hand, growth inhibitory were minimal normal astrocytes. Acridine orange ethidium bromide staining (AO/EB) revealed induces...
Abstract Interleukin‐10 (IL‐10) is an anti inflammatory cytokine involved in the ongoing coronary inflammation and related patho‐physiological processes. The piece of work presented herein aimed at investigating possible association polymorphisms IL‐10 promoter with Saudi cardiovascular disease (CVD) patients. study included 80 confirmed CVD patients diabetes 75 healthy control individuals both men women. Concentration serum samples were measured by ELISA method. For single nucleotide...
Background:The present study consisted of a total 200 subjects (100 confirmed coronary artery disease (CAD) patients), both men and women, 100 healthy control individuals.Methods: Serum concentration IL-6 RANTES were measured by enzyme-linked immunosorbent assay kit.For SNPs analysis, sanger method DNA sequencing was followed. Results:We observed variable numbers SNP sites at -174 G/C, -572 -597 G/A in -28 C/G -109 C/T promoters CAD patients compared with individuals.However, the changes...
Natural killer (NK) cells are the potential modulators of inflammatory reactions that exert several unique biological effects and could lead to future adverse events coronary artery disease (CAD).The purpose this study was find out possible association modulation in NK cell, TNK cells, T B tumor necrosis factor alpha (TNF-α) CAD patients various forms myocardial infarction.The present included total 190 subjects (98 confirmed both men women 92 healthy control individuals). Serum...
Abstract Neopterin has been considered as an important marker of cellular inflammation. The primary objective the current study was to determine role neopterin in cardiovascular disease and its association with other well known cardiac markers. composed total 200 subjects (100 confirmed coronary artery (CAD) patients, 50 recently diagnosed, managed CAD patients) both men women 100 healthy control individuals matching age weight. Serum analysis done using commercial available ELISA kits....
ABSTRACT The purpose of the current study was to find out possible changes polymorphic site at promoter region IL‐18 gene in Saudi CAD patients. We have also measured serum level out, likely association between its and site. present included total 197 subjects (98 confirmed patients both men women 99 healthy control individuals). Serum concentration by enzyme linked immuno‐sorbent assay. For SNPs analysis, sanger method DNA sequencing followed. observed variable numbers −137 C/G, −607 A/C,...
Interleukin-1β (IL-1β) is an inflammation-causing cytokine that exerts several unique biological effects and could lead to future adverse events of CAD. The piece work presented herein aimed at investigating possible association IL-1β levels its polymorphic site viz. −511 −31 promoter region in Saudi CAD patients. study included 155 confirmed patients 80 healthy control individuals both men women. Concentration the patients' serum was measured by ELISA method. For single nucleotide...
Objectives: The present study compares the role and significance of non-high density lipoproteins (non-HDL) cholesterol level in pre-diabetic diabetic patients. This also non-HDL between males females with different age groups as well. Methods: An observational was conducted among 3830 randomly selected individuals to envisage association other lipid parameters age, gender, status. On basis health status, subjects were classified diabetic, normal. Fasting blood samples collected analyzed on...