Arterial hypertension (AH) and exertional headache (EHA) are comorbidities. The article presents a nonsystematic review focused on studying the AH+EHA phenotype. authors addressed history of phenotype, several theories about its pathophysiological causes (psychosomatic, neuroanatomical, baroreflector). protective "hypertension-associated hypoalgesia" mechanism change in AH chronization, difficulties differential diagnosis described. phenotype requires further study since incidence is quite...

According to the recent data, nitric oxide (NO) is a chemical messenger that mediates functions such as vasodilation and neurotransmission, it also possesses antimicrobial antitumoral activities. Nitric has been implicated in neurotoxicity associated with stroke neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, penile erection. We searched for full-text English publications Pubmed SNPedia databases using keywords combined word searches (nitric oxide,...

The aim of the present research was to evaluate main characteristics tempo-rhythm in healthy adults.Materials and methods: A total 33 adult volunteers (20 males 13 females) participated study.The technique involved wrist tapping on surface device (Android smartphone), followed by registration time parameters this process original program based modified "Method exogenous rhythmic stimulation influence an individual human rhythm."The reference boundaries were studied. Conclusion:The obtained...

Cognitive disorders are often associated with epilepsy and a result of combination various factors.This review describes scientific advances in the field cognitive patients juvenile myoclonic (JME), most common form idiopathic generalized epilepsy.Data this were collected through an extensive literature search available full-text publications PubMed eLIBRARY.RU databases.We selected four theories origin impairment JME for discussion, based on analysis studies.Our findings highlight...

The aim of this review was to analyze domestic and foreign publications reflecting the main existing theories tension-type headache (TTH) development search for common pathogenetic links TTH with arterial hypertension (AH) as potential triggers clinical AH phenotype. Methods. We searched articles in databases (eLibrary.ru, Web Science, Scopus, PubMed, Clinical Case) by keywords. Search depth – 2006–2021. Results. analysis allowed us identify leading underlying TTH: psychogenic, vascular,...

The association of epilepsy with mental illness has been described in recent years.Scientists are trying to relate certain epilepsies, such as juvenile myoclonic (JME), personality traits marked by emotional instability.The goal this review is evaluate the scientific literature about nonpsychotic psychiatric disorders JME patients, most common form idiopathic generalized (IGE).Data were collected through an extensive search available full-text publications PubMed, Springer, Clinical Keys and...

In recent years, the genetics of juvenile myoclonic epilepsy (JME) has been actively studied; association JME with carriage polymorphic allelic variants BRD2 (EJM3 locus) and GJD2 (EJM2 genes established. Objective: to establish risk factors for in terms a genetic predisposition; specifically, rs206787 rs516535 gene rs3743123 gene. Patients methods: Examinations were made 79 patients 150 healthy volunteers, who Caucasian resided Siberian Federal District (SFD) underwent determination single...

Convulsive syndrome is an urgent, potentially life-threatening condition in neurological, paediatric and general practice. Over the past decade, reconsideration has been committed relation to defi nition of epilepsy, epileptic syndromes, including convulsive with simultaneous expansion arsenal medicinal products for cessation seizures children adults. In this connection, we have prepared lecture comprising two parts: first part considers nition, pathogenesis, aetiology diagnosis syndrome....

Mutations of POLG gene can cause a variety clinical manifestations, including autosomal recessive or dominant mitochondrial diseases. The article presents case demonstrating the difficulty differential diagnosis POLG-associated disease and juvenile myoclonic epilepsy. demonstrates importance molecular genetic in idiopathic generalized epilepsy with atypical features for timely administration appropriate therapy minimize development adverse side reactions.

Background. An association between juvenile myoclonic epilepsy (JME) and nonpsychotic psychiatric cognitive disorders has been described in recent years. Scientists are trying to link JME with certain personality traits marked by emotional instability.

Aim ― To study the influence of anxiety on parameters wrist tapping in normal conditions and juvenile myoclonic epilepsy (JME). Material Methods We evaluated 105 people aged 16 to 55 years old (average: 31.6±10.2 years). The sample was comprised two groups: first (I) group – healthy volunteers (n=60); second (II) patients with JME (n=45). Every stratified into subgroups: subgroup Ia (n=33) without symptoms anxiety; Ib (n=27) subclinical IIa (n=19) IIb (n=26) anxiety. Wrist were studied using...

Tension-type headache (TTH) is the most common form of primary headache. The aim review to analyse research on epidemiology and triggers TTH. search for full-text articles in Russian English languages published within past decade was performed E-Library, PubMed, Springer, ClinicalKey Google Scholar databases. A total seven forty-two foreign epidemiological studies have been analysed. Thus, global prevalence TTH amounts 32% (4.4% among these cases are chronic TTH). In Russia, its 52.4%....

Juvenile myoclonic epilepsy (JME) is a well-defined sub-syndrome of idiopathic generalized/genetic epilepsy, usually presenting in adolescence and characterized by jerks, predominately the arms, associated with tonic-clonic seizures less often generalized absences.Although evidence base for relationship between JME sleep disorders weak, most experts regard as an actual comorbidity.This paper reviews literature underpinning development patients.Data that report causes problems patients are...

Melatonin - the most well studied factor of circadian rhythm attracts much intereset in regard to a disease-modifying therapy for epilepsy. In some forms epilepsy, dysrhythmias and sleep disorders can trigger development epileptic seizures, while others seizures develop from REM-phase sleep. The aim is review analyze studies on efficacy safety exogenous melatonin as an additional medication pediatric adult patients with Materials methods . search was conducted Russian English articles...

The review focuses on the problem of personality disorders that arise in patients with pharmaco-resistant epilepsy after neurosurgical resections. We analyzed 47 research articles, selected by keywords from Russian and international databases for 20102017. It was found that, despite achievements surgery high percentage remission postoperative period, remains important. most frequent are anxiety depression, which greatly exacerbate course period make it difficult patient to adapt society...

Th e convulsive syndrome is an urgent and potentially life-threatening condition in neurological, pediatric general medical practice. Over the past decade, there has been a reconsideration of definition epilepsy epileptic syndromes, including syndrome. Additionally, arsenal pharmaceuticals for relief seizures children adults expanded. In this connection, lecture was created two parts: second part will consider treatment at pre-hospital hospital stages. intended neurologists, pediatricians,...