A5090217386- Cancer Cells and Metastasis
- Mesenchymal stem cell research
- 3D Printing in Biomedical Research
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- CRISPR and Genetic Engineering
- Neuroendocrine regulation and behavior
- Telomeres, Telomerase, and Senescence
- Cancer-related molecular mechanisms research
- Genetics, Aging, and Longevity in Model Organisms
- T-cell and Retrovirus Studies
- Cellular transport and secretion
- Cellular Mechanics and Interactions
- Stress Responses and Cortisol
- Osteoarthritis Treatment and Mechanisms
- Cancer Research and Treatments
- Long-Term Effects of COVID-19
- Cytokine Signaling Pathways and Interactions
- Trypanosoma species research and implications
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Lysosomal Storage Disorders Research
- Connective Tissue Growth Factor Research
- Sarcoma Diagnosis and Treatment
- bioluminescence and chemiluminescence research
- Cancer-related gene regulation
University of Nottingham
2020-2024
Kazan Federal University
2010-2024
Institute of Chemical Biology and Fundamental Medicine
2022
Whittemore Peterson Institute
2014
Myalgic encephalomyelitis, also known as chronic fatigue syndrome or ME/CFS, is a multifactorial and debilitating disease that has an impact on over 4 million people in the United States alone. The pathogenesis of ME/CFS remains largely unknown; however, genetic predisposition been suggested. In present study, we used DNA single-nucleotide polymorphism (SNP) chip representing 906,600 SNPs to analyze from subjects healthy controls. To best our knowledge, this study represents most...
The improvement of human living conditions has led to an increase in average life expectancy, creating a new social and medical problem—aging, which diminishes the overall quality life. aging process body begins with activation effector signaling pathways cells, resulting loss their normal functions deleterious effects on microenvironment. This, turn, leads chronic inflammation similar transformations neighboring cells. cumulative retention these senescent cells over prolonged period results...
The use of mesenchymal stem cells (MSCs) has been shown to be promising in chronic disorders such as diabetes, Alzheimers dementia, Parkinsons disease, spinal cord injury and brain ischemia. Recent studies revealed that human tooth germs (hTG) contain MSCs which can easily isolated, expanded cryo-preserved. In this report, we isolated germ (hTGSCs) with MSC characteristics from third molar germs, cryo-preserved them at -80°C for 6 months, evaluated their surface antigens, expression...
Recent data described that patients with lysosomal storage disorders (LSDs) may have clinical schizophrenia (SCZ) features. Disruption of lipid metabolism in SCZ pathogenesis was found. Clinical features been demonstrated several (LSDs). Taking into account the critical role function for neuronal cells’ dysfunction could be proposed pathogenesis. The current study analyzed enzyme activities and alpha-synuclein level blood late-onset SCZ. In total, 52 SCZ, 180 sporadic Parkinson’s disease...
Recent discovery of an association low serum melatonin levels with relapse in multiple sclerosis (MS) opens a new horizon understanding the pathogenesis this disease. Skin is main organ for sensing seasonal changes duration sunlight exposure. Level production dependent on light The molecular mechanisms connecting peripheral (skin) exposure and developing brain inflammation have not been investigated. We hypothesize that there connection between reaction skin to risk MS cause inflammation,...
According to the recent data, nitric oxide (NO) is a chemical messenger that mediates functions such as vasodilation and neurotransmission, it also possesses antimicrobial antitumoral activities. Nitric has been implicated in neurotoxicity associated with stroke neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, penile erection. We searched for full-text English publications Pubmed SNPedia databases using keywords combined word searches (nitric oxide,...
Last data described that patients with lysosomal storage disorders (LSDs) may have clinical schizophrenia (SCZ). The dysfunction in SCZ pathogenesis, particularly, due to the critical role of function for neuronal cells could be proposed. current study focused on estimation enzyme activities and alpha-synuclein level blood late-onset SCZ. 52 SCZ, 180 sporadic Parkinson’s disease (sPD) patients, 176 controls were recruited. enzymatic activity enzymes associated mucopolysaccharidosis...
The enhancement of human living conditions has resulted in an increase average life expectancy, giving rise to a novel social and medical challenge: aging, which diminishes the overall quality life. aging process body begins through activation effector signaling pathways cells, loss their normal functions deleterious effects on microenvironment, leads chronic inflammation similar transformation neighboring cells. cumulative retention these senescent cells over prolonged period results...
Abstract Background N6-methyladenosine (m 6 A) is the most common internal RNA modification and involved in regulation of protein expression. AlkB family member 5 (ALKBH5) a m A demethylase. Given important role biological mechanisms, its regulators, have been implicated many disease processes, including cancer. However, contribution ALKBH5 to invasive breast cancer (BC) remains poorly understood. The aim this study was evaluate clinicopathological value BC. Methods Publicly available data...