Д. И. Абдулганиева
- Inflammatory Bowel Disease
- Rheumatoid Arthritis Research and Therapies
- Spondyloarthritis Studies and Treatments
- Microscopic Colitis
- Psoriasis: Treatment and Pathogenesis
- Liver Disease Diagnosis and Treatment
- Liver Diseases and Immunity
- Long-Term Effects of COVID-19
- Autoimmune and Inflammatory Disorders Research
- COVID-19 Clinical Research Studies
- Systemic Sclerosis and Related Diseases
- Autoimmune and Inflammatory Disorders
- Eosinophilic Esophagitis
- Healthcare Systems and Public Health
- Pharmacological Effects of Natural Compounds
- Systemic Lupus Erythematosus Research
- Medical History and Innovations
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Dermatological and COVID-19 studies
- Clostridium difficile and Clostridium perfringens research
- Medical and Biological Sciences
- Immunodeficiency and Autoimmune Disorders
- Inflammasome and immune disorders
- Musculoskeletal Disorders and Rehabilitation
- Myofascial pain diagnosis and treatment
Kazan State Medical University
2016-2025
Republican Clinical Hospital of the Ministry of Health of the Republic of Tatarstan
2015-2025
Ministry of Health of the Russian Federation
2015-2025
Dagestan State Medical Academy
2018-2025
Agostino Gemelli University Polyclinic
2023
Kazan Federal University
2019-2021
Hospital de São João
2021
Sechenov University
2019
Volgograd State Medical University
2019
Kursk State Medical University
2019
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In mid-2021, the SARS-CoV-2 (Severe Acute Respiratory coronavirus 2) infection, which caused disease (COVID-19) pandemic, affected more than 157 million people in all regions of world and led to 3.2 deaths. It is assumed that elderly age, uncontrolled inflammation, anti-inflammatory therapy, comorbid pathology, genetic other factors can potentially lead an increase “sensitivity” viral bacterial infections, including SARS-CoV-2. The new version recommendations Association Rheumatologists...
Background : Epidemiological studies performed in different countries have identified a number of trends that allow to predict the problems related prevalence inflammatory bowel diseases (IBD), their severity and healthcare resources utilization. Aim To present comparative results two large epidemiological IBD Russian Federation (RF), i.e. ESCApe ESCApe-2. Materials methods Two multicenter cross-sectional cohort with similar design were at three-year interval. The had common aim: identify...
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The National Registry of Patients with Inflammatory Bowel Disease (IBD) in the Russian Federation was established to study epidemiological and clinical characteristics patients evaluate actual practice medical surgical treatment. AIM : analyze data IBD including demographic characteristics, status patients, frequency use various classes drugs response treatment, survival rates advanced therapy reasons for their cancellation. METHODS from May 2017 August 2021, depersonalized 3827 adult...
The aim – to evaluate the clinical effectiveness, safety, pharmacokinetics, pharmacodynamics, and immunogenicity of seniprutug (BCD-180) in patients with radiographic active axial spondyloarthritis (r-axSpA, or ankylosing spondylitis). Subjects methods . 260 r-axSpA inadequate response nonsteroidal anti-inflammatory drugs (NSAIDs) were randomized into three groups: at doses 5 mg/kg 7 mg/kg, placebo. BCD-180 was administered on weeks 0–12–36. Patients placebo group switched a dose week 24...
Aim. The practical guidelines are intended for primary care physicians, general practitioners, paediatricians, gastroenterologists and internists to advance the treatment prevention of gastroenterological diseases in adults children therapies with probiotics, prebiotics, synbiotics their enriched functional foods. Key points. Probiotics live microorganisms that sustain health host when supplied adequate amounts. Prebiotics include human-indigestible but accessible gut microbiota substances...
Abstract Background Inflammatory bowel diseases (IBD), which include Crohn’s disease (CD) and ulcerative colitis (UC), are an urgent problem of modern gastroenterology, is associated with increase in morbidity, a lifelong recurrent course, the prevalence mainly among young people working age. Extracellular manifestations CD UC damage to bone system form impaired mineralization possible development osteoporosis (OP). In this regard, patients IBD have high risk developing osteoporotic...
The search for new therapeutic options the treatment of systemic sclerosis (SSc) is an urgent issue in rheumatology. article presents results double-blind, randomized, placebo-controlled phase III clinical trial BCD-132-5/LIBERIUS on efficacy and safety divozilimab (BCD-132) SSc. Objective : to investigate patients with SSc compared placebo. Material methods . After enrolment study, received or placebo 48 weeks, after which they were switched open-label therapy until week 96. Results...
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The aim of the study is to evaluate efficacy, safety and immunogenicity divozilimab (DIV), anti-CD20 monoclonal antibody, in patients with systemic sclerosis (SS). Materials methods . Patients SS according ACR/EULAR (American College Rheumatology/ European Alliance Associations for Rheumatology) 2013 criteria modified Rodnan skin score (mRSS) ≥10 ≲20 forced vital capacity (FVC) ≥40% from due took part study. Infusions DIV 250 mg were administered on weeks 0 2, 500 – week 24 subsequent use...
Serum cytokine levels were explored in a combined group of patients with autoimmune liver diseases (AILDs) and separately hepatitis (AIH) overlap syndrome. Overall, 60 AILD, among them 32 AIH 28 syndrome, included the cross-sectional study. measured at baseline compared to those 21 healthy controls. Patients AILD had significantly higher IL-6 (0.70 (range 0.17–99.86) 0.40 0.14–2.65) controls,<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"...
Summary Post- COVID syndrome refers to the long-term consequences of a new coronavirus infection COVID-19, which includes set symptoms that develop or persist after COVID-19. Symptoms gastrointestinal disorders in post- syndrome, due chronic infl ammation, organ damage, prolonged hospitalization, social isolation, and other causes, can be persistent require multidisciplinary approach. The presented clinical practice guidelines consider main preventive therapeutic diagnostic approaches...
Abstract Background Sarcopenia is a progressive pathological condition which can present in inflammatory bowel disease (IBD) together with changes body composition. Aim To provide ultrasound assessment of muscle mass and bioimpedance analysis composition patients IBD. Methods: Material Method The study included 102 IBD, 50 (49%) ulcerative colitis (UC), 52 (51%) Crohn's (CD), 10 persons formed the control group (CG). average age IBD was 39,5 [28,5; 50] year, CG – 37 [26; 38] years. There...
The Russian Cross-disciplinary Consensus on the diagnositic and treatment of spondyloarthritis (SpA) in inflammatory bowel diseases (IBD) was prepared initiative Loginov Moscow Clinical Scientific Center, using Delphic system. Its purpose to consolidate opinions experts most actual issues diagnosis concomitant immuno-inflammatory (SpA IBD). An interdisciplinary approach is provided by participation leading gastroenterologists rheumatologists. working group analyzed domestic foreign...
To assess the muscle mass of patients with inflammatory bowel disease (IBD) using ultrasound. 102 IBD hospitalized in gastroenterology department Republican Clinical Hospital (Kazan) were involved study. Among them, 49% ulcerative colitis, 51% Crohn's disease, 10 people made up control group (CG). The median age was 39.5 [28.5; 50] years, CG - 37 [26; 38] years. There 52 (51%) women and 5 (50%) group. Patients examined to body index (BMI), mid-upper arm circumference (MUAC, cm) mid-thigh...
Aim . The clinical guidelines are intended to provide information support for making decisions by gastroenterologists, general practitioners and internists that will improve the quality of medical care patients with non-alcoholic fatty liver disease, taking into account latest data principles evidence-based medicine. Key points Clinical contain about current views on etiology, risk factors pathogenesis nonalcoholic peculiarities its course. Also given recommendations methods laboratory...
Aim . To optimize the choice of treatment strategies by physicians and gastroenterologists to improve prevention small intestinal bacterial overgrowth (SIBO) in adults. Key points SIBO is a condition characterized an increased amount and/or abnormal composition microbiota intestine. Clinically, syndrome manifested nonspecific gastroenterological complaints development malabsorption syndrome. Most often, associated with various chronic non- infectious diseases (both gastrointestinal tract,...
Aim. This paper presents guidelines on the diagnostics and treatment of eosinophilic esophagitis, which can be used by practitioners in their everyday practice. Summary. Eosinophilic esophagitis (EoE) is a chronic immune-mediated disease esophagus characterized symptoms esophageal dysfunction pronounced infiltration mucosa. The EoE based clinical manifestations (dysphagia, food impaction, chest pain regardless swallowing), as well combination endoscopic histological signs. diagnostic...
Rheumatoid arthritis (RA) is the most frequent immunoinflammatory (autoimmune) rheumatic disease characterized by chronic erosive and systemic damage to internal organs. The data obtained in course of basic research on deciphering mechanisms action methotrexate (MT) materials numerous randomized placebocontrolled trials, observational studies national registries have strengthened position MT as “gold standard” RA pharmacotherapy a key component “Treatment Target” strategy. This was basis for...