A5015361679- Retinal Diseases and Treatments
- Ocular Diseases and Behçet’s Syndrome
- Animal Virus Infections Studies
- Vasculitis and related conditions
- Retinal Imaging and Analysis
- Retinal and Optic Conditions
- Virus-based gene therapy research
- Viral gastroenteritis research and epidemiology
- Ophthalmology and Visual Impairment Studies
- Systemic Lupus Erythematosus Research
- melanin and skin pigmentation
- Olfactory and Sensory Function Studies
- Biochemical Analysis and Sensing Techniques
- Atherosclerosis and Cardiovascular Diseases
- Metabolomics and Mass Spectrometry Studies
- Intraocular Surgery and Lenses
Humboldt-Universität zu Berlin
2023-2024
Charité - Universitätsmedizin Berlin
2023-2024
Freie Universität Berlin
2023-2024
University Medical Center Hamburg-Eppendorf
2022
Universität Hamburg
2022
Macular edema (ME) remains a primary cause of visual deterioration in uveitis. Visual acuity (VA) can often be maintained using corticosteroid depot systems. This study evaluated the efficacy fluocinolone acetonide (FAc) intravitreal implant (ILUVIEN®) treating non-infectious uveitis real-world data. retrospective analysis included 135 eyes subdivided into responders and non-responders. Central retinal thickness (CRT), VA, intraocular pressure (IOP) were followed over time. A significant...
There is early evidence of extraocular systemic signals effecting function and morphology in neovascular age-related macular degeneration (nAMD). The prospective, cross-sectional BIOMAC study an explorative investigation peripheral blood proteome profiles matched clinical features to uncover determinacy nAMD under anti-vascular endothelial growth factor intravitreal therapy (anti-VEGF IVT). It includes 46 patients stratified by the level disease control ongoing anti-VEGF treatment. Proteomic...
Purpose: We aimed to determine the impact of artificial sweeteners (AS), especially saccharin, on progression and treatment efficacy patients with neovascular age-related macular degeneration (nAMD) under anti-vascular endothelial growth factor (anti-VEGF-A) treatment. Methods: In a cross-sectional study involving 46 nAMD undergoing intravitreal anti-VEGF therapy, 6 AS metabolites were detected in peripheral blood using liquid chromatography - tandem mass spectrometry (LC-MS/MS). Disease...
Abstract Purpose To investigate the xenobiotic profiles of patients with neovascular age-related macular degeneration (nAMD) undergoing anti-vascular endothelial growth factor (anti-VEGF) intravitreal therapy (IVT) to identify biomarkers indicative clinical phenotypes through advanced AI methodologies. Methods In this cross-sectional observational study, we analyzed 156 peripheral blood features in a cohort 46 nAMD stratified by choroidal neovascularization (CNV) control under anti-VEGF IVT....
Zusammenfassung Entzündliche Veränderungen der Netzhautgefäße können auf ein breites Spektrum von Ursachen zurückgeführt werden. Dazu zählen Infektionen, intraokulare und systemische Autoimmunprozesse, Allgemeinerkrankungen sowie iatrogene Faktoren. Da das Endothel Retinakapillaren die innere Blut-Retina-Schranke bildet, ist eine Störung dieser Struktur unmittelbar mit Konsequenzen für den Flüssigkeitselektrolythaushalt Netzhaut verbunden. Als klinische Folgen sich Leckagen Makulaödem...
To assess the results of partial monovision (PMV) in comparison to a bilateral monofocal implantation (MMV).
Adalimumab, an anti-TNF-α biologic agent, has emerged as a principal treatment option for patients with non-infectious uveitis. The influence of adalimumab anti-drug antibodies (AAA) on the efficacy therapy is not yet fully understood. We aim to understand their clinical implications in context therapeutic drug monitoring and factors contributing formation these antibodies. conducted retrospective analysis 114 uveitis who developed AAA while undergoing therapy. Among AAA-positive patients,...