A5000834355- Plant Disease Resistance and Genetics
- Plant Virus Research Studies
- Animal Virus Infections Studies
- HIV Research and Treatment
- Herpesvirus Infections and Treatments
- Virology and Viral Diseases
- Plant Pathogenic Bacteria Studies
- Immune Cell Function and Interaction
- HIV/AIDS Research and Interventions
- Research in Cotton Cultivation
- Plant Pathogens and Resistance
University of Toronto
2017-2018
A major barrier to a human immunodeficiency virus type 1 (HIV-1) infection cure is the establishment of viral reservoir in spite combined antiretroviral therapy (cART). It unclear how HIV-specific cytotoxic T lymphocytes (CTLs) influence size early HIV infection. Twenty-eight subjects with were recruited receive cART and followed for 48 weeks. reservoirs peripheral CD4+ cells measured by cell-associated proviral DNA outgrowth cultures determined at baseline after weeks cART. At baseline,...
Attenuated varicella zoster virus (VZV) is a promising vector for recombinant vaccines. Because human immunodeficiencyvirus (HIV) vaccines are believed to require mucosal immunogenicity, we characterized VZV-specific humoral immunity following VZVOka vaccination.Adult Kenyan VZV-seropositive women (n = 44) received single dose of the live vaccine. The anamnestic responses were followed longitudinally in both plasma and secretions using an in-house glycoprotein enzyme-linked immunosorbent...