A5016285103- Fullerene Chemistry and Applications
- RNA Interference and Gene Delivery
- Graphene research and applications
- Immunotherapy and Immune Responses
- Immune Cell Function and Interaction
- COVID-19 Clinical Research Studies
- Boron and Carbon Nanomaterials Research
- Advancements in Battery Materials
- Hematopoietic Stem Cell Transplantation
- Retinoids in leukemia and cellular processes
- Bone health and treatments
- Advanced Drug Delivery Systems
- Estrogen and related hormone effects
- Computational Drug Discovery Methods
- SARS-CoV-2 and COVID-19 Research
- Nanoparticle-Based Drug Delivery
- Advanced Materials and Mechanics
- Transportation Safety and Impact Analysis
- PI3K/AKT/mTOR signaling in cancer
- Quantum Electrodynamics and Casimir Effect
- Micro and Nano Robotics
- Synthesis and Properties of Aromatic Compounds
- Lymphatic System and Diseases
- Supramolecular Self-Assembly in Materials
- Nuclear Receptors and Signaling
Hebei Medical University
2024
First Affiliated Hospital of Hebei Medical University
2024
Capital Medical University
2012-2024
Beijing National Laboratory for Molecular Sciences
2021-2024
Chinese Academy of Sciences
2021-2024
University of Chinese Academy of Sciences
2024
Institute of Chemistry
2021-2024
Air Force Medical University
2024
Xijing Hospital
2024
Taiyuan University of Technology
2022
Micro/meso-porous carbon nanofibers have been successfully prepared and directly adopted as a supercapacitor electrode material with high specific capacitance, area normalized capacitance excellent cycling stability.
Reactive oxygen species (ROS)-responsive nanocapsules for cancer drug delivery were engineered from green tea polyphenol–metal networks.
Polydopamine nanoparticles (PDA NPs) were prepared<italic>via</italic>dopamine self-polymerization; then, tumor cell lysate (TCL) was covalently attached onto the PDA NPs.
A novel bone-targeted delivery systems based on nanocapsules was developed utilizing a Zeolitic Imidazolate Framework (ZIF-8) as template and catechol-modified gelatin wall material. targeting ligand facilely conjugated the surface of nanocapsules. Simvastatin encapsulated within with loading 37.9%. Hydroxyapatite binding in vivo biodistribution drug-loaded were investigated.
A retrospective study was conducted to summarize the clinical information of childhood infections during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic.Children with SARS-CoV-2 infection in 11 hospitals from three provinces South China were included study. Clinical collected and compared children adults infected by Wuhan.In total, 52 enrolled, including 28 boys. The median age 9 years (interquartile range [IQR], 4-12); 44.2% cases clustered occurrences, 40.4% patients...
BACKGROUND: Immune thrombocytopenia (ITP) is a bleeding disorder characterized by antibody‐opsonized platelets (PLTs) being prematurely destroyed macrophages in the reticuloendothelial system. T helper (Th) cells and different Th cytokines play an important role pathophysiology of ITP. As immunomodulators, adipose‐derived mesenchymal stem (ADSCs) regulate show therapeutic effects autoimmune diseases. However, it not clear how ADSCs affect In this study, we explored specific on ITP mice....
This study aimed to investigate the efficacy of polydopamine nanoparticles (Pdop-NPs) as a subcutaneous antigen delivery vehicle in antitumor therapy. The were prepared by self-polymerization dopamine an aerobic and weak alkaline solution, tumor model antigen-ovalbumin (OVA) was grafted onto form OVA@Pdop (OVA@Pdop-NPs). particle size OVA@Pdop-NPs 232.8 nm with zeta potential −23.4 mV, loading capacity OVA protein 754 μg mg–1. essentially noncytotoxic even demonstrated slightly viability...
It is vital to construct luminescent single-molecule magnets (SMMs) and explore their applications in quantum computing technique magneto-luminescence devices. In this work, we report a magnet with thermally activated delayed fluorescence (TADF) based on metallofullerene DyY2N@C80. DyY2N@C80 was constructed by integrating dysprosium yttrium ions into fullerene cage. Magnetic results suggest that exhibits magnetic hysteresis loops below 8 K originating from the Dy3+ ion. Moreover, TADF...
Tubular fullerenes can be considered as end-capped carbon nanotubes with accurate structure, which are promising nanocarbon materials for advanced single-molecule electronic devices. Herein, we report the synthesis and characterization of a metallofullertube Ce2 @D5 (450)-C100 , has tubular C100 cage nanotube segment two fullerene end-caps. As there structure correlations between spherical @Ih -C80 their structure-property relationship been compared by means experimental theoretical methods....
Abstract This paper reports the discovery of a magnetophotoluminescence response in metallofullerene Y 3 N@C 80 triggered by triplet excited state. In experiments, exhibits magnetic field‐dependent (0→±42 T) phosphorescence emission at 4.2 K. Crucially, with increasing field, peaks shift to longer wavelengths owing Zeeman effect. Further, nanoring [9]CPPH is employed modulate through host−guest interaction. The circularly polarized spectra and ⊂[9]CPPH are investigated further reveal their...
A method for encapsulation of individual tumor cells with an epigallocatechin-3-gallate (EGCG)-Al(iii) coordination layer, which can be used as potential vaccines, was developed. The interaction between microparticle vaccines and dendritic investigated in vitro. microparticles (∼10 μm) were efficiently internalized by DCs enhanced uptake efficiency via actin polymerization clathrin-mediated endocytosis.
Erbium metallofullerenes exhibit near-infrared photoluminescence from the Er3+ ions, which has potential applications in telecommunications, optical devices and bioscience. In this manuscript, we report construction of a supramolecular complex metallofullerene Er3N@C80 cycloparaphenylene [12]CPP to adjust through host-guest interactions. Moreover, shows multiwavelength luminescence property. Mass spectrometry, electrochemical measurements proton NMR spectroscopy were used characterize...
The prediction of the estrogen receptor (ER) and androgen (AR) activity a compound is quite important to avoid environmental exposures endocrine-disrupting chemicals. Estrogen Androgen Receptor Database (EARDB, http://eardb.schanglab.org.cn/) provides unique collection reported ERα, ERβ, or AR protein structures known small molecule modulators. With user-uploaded query molecules, molecular docking based on multi-conformations single target will be performed. Moreover, 2D similarity search...
In this study, we investigated the combined use of cytokine-induced killer (CIK) cells and cyclosporine A (CsA) to treat a mouse model aplastic anemia (AA). CIK were cultured injected alone or in combination with CsA into mice that had previously been induced AA by busulfan interferon-γ (IFN-γ). The cell-treated group survival rate 55%, which was similar 60% observed CsA-treated group. showed as high 90%, while none no-treatment survived end experiment. produced multiple cytokines, including...
Abstract Tubular fullerenes can be considered as end‐capped carbon nanotubes with accurate structure, which are promising nanocarbon materials for advanced single‐molecule electronic devices. Herein, we report the synthesis and characterization of a metallofullertube Ce 2 @ D 5 (450)‐C 100 , has tubular C cage nanotube segment two fullerene end‐caps. As there structure correlations between spherical I h ‐C 80 their structure–property relationship been compared by means experimental...
Hereditary hemochromatosis (HH) is an iron overload disease that caused by mutations in genes regulating homeostasis, leading to excessive absorption and toxic accumulation of the liver, pancreas, skin, heart, joints, pituitary gland [1]. HH a multisystemic with typical clinical manifestations including cirrhosis, diabetes, skin pigmentation With development genetic testing methods detection affected individuals different regions, rare gene have been discovered [2-4]. A 53-year-old man was...