- Plant Molecular Biology Research
- Chromosomal and Genetic Variations
- Plant tissue culture and regeneration
- Plant Reproductive Biology
- Plant Virus Research Studies
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Plant Parasitism and Resistance
- Genomics and Phylogenetic Studies
- Plant nutrient uptake and metabolism
- CRISPR and Genetic Engineering
- Photosynthetic Processes and Mechanisms
Indian Institute of Science Education and Research Thiruvananthapuram
2016-2024
West Virginia State University
2023
CENH3 variation mediates parental centromere imbalance.
Abstract Epimutations are heritable changes in gene function due to loss or gain of DNA cytosine methylation chromatin modifications without the sequence. Only a few natural epimutations displaying discernible phenotypes documented plants. Here, we report cadastral gene, SUPERMAN ( SUP ), showing striking despite normal transcription, discovered tetraploid, and subsequently eleven diploid Arabidopsis genetic accessions. This lois lane lol ) epialleles behave as recessive mendelian alleles...
Abstract Uniparental genome elimination is a dramatic case of centromeric failure, resulting in the postzygotic loss parental chromosome set. Genome partitioning during cell division relies on centromere attachment to spindle fibers through kinetochores. Centromeres are epigenetically specified by CENP-A (CENH3), conserved specific histone H3 variant. In Arabidopsis, CENH3 modification results haploid inducers, whose eliminated frequently when crossed wild type. To investigate underlying...
Abstract The gametophyte to sporophyte transition facilitates the alternation of generations in a plant life cycle. epigenetic regulators DEMETER(DME) and MEDEA(MEA) synergistically control central cell proliferation differentiation, ensuring proper sporo-phyte Arabidopsis . Mutant alleles DME MEA are female lethal, eluding recovery recessive homozygotes examine their role sporophyte. Here, we exploited paternal transmission these mutant coupled with CENH3-haploid inducer generate mea -1;...
Cantil is reported as a new-found organ specific to the model plant Arabidopsis thaliana that prominent only in short-day-grown wild-type accessions or long-day-grown genetic mutants with delayed vegetative reproductive transition. Here, we show cantils (previously known nubbins) arise one of many phenotypic consequences aneuploidy resulting from chromosome dosage imbalances polyaneuploids despite normal transition long-day photoperiods. Without demonstrated function adaptive significance,...