A5088374967- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Supramolecular Chemistry and Complexes
- Molecular Sensors and Ion Detection
- Luminescence and Fluorescent Materials
- Supramolecular Self-Assembly in Materials
- Metal-Organic Frameworks: Synthesis and Applications
- Porphyrin and Phthalocyanine Chemistry
- Synthesis and Properties of Aromatic Compounds
- Crystallography and molecular interactions
- Amino Acid Enzymes and Metabolism
- Magnetism in coordination complexes
- Molecular Junctions and Nanostructures
- Enzyme Structure and Function
- Nanoplatforms for cancer theranostics
- Advanced biosensing and bioanalysis techniques
- Ferroelectric and Piezoelectric Materials
- Multiferroics and related materials
- Photoreceptor and optogenetics research
- Fullerene Chemistry and Applications
- Organic Electronics and Photovoltaics
- Molecular spectroscopy and chirality
- Photochromic and Fluorescence Chemistry
- Biochemical and Molecular Research
- Topic Modeling
Nankai University
2020-2025
Ankang City Central Hospital
2025
Northwestern University
2018-2023
Peking University
2012-2020
Beijing National Laboratory for Molecular Sciences
2012-2020
Wuhan Institute of Technology
2016-2019
Central South University of Forestry and Technology
2019
Central South University
2019
National Institute for Materials Science
2018
University of Wollongong
2018
Mechanically interlocked molecules are likely candidates for the design and synthesis of artificial molecular machines. Although polyrotaxanes have already found niche applications in exotic materials with specialized mechanical properties, efficient synthetic protocols to produce them precise numbers rings encircling their polymer dumbbells still lacking. We report assembly line-like emergence poly[n]rotaxanes increasingly higher energies by harnessing pumps deliver pairs cyclical...
Macroscopic electric motors continue to have a large impact on almost every aspect of modern society. Consequently, the effort towards developing molecular
Completely understanding the working mechanisms of sophisticated supramolecular self-assembly exhibiting competing paths is very important for chemists en route to acquiring ability constructing systems with controlled structures and designed functions. Here, self-aggregation behaviors an N-heterocyclic aromatic dicarboximide molecule 1, boasting two that give rise different exhibit distinct thermodynamic features, are carefully examined. First, a group H-aggregates observed when providing...
Along with the advent of supramolecular chemistry, research on fullerene receptors based noncovalent bonding interactions has attracted a lot attention. Here, we present design and synthesis cationic molecular cage: cyclophane composed two tetraphenylporphyrins, bridged face-to-face by four viologen units in rhomboid prismatic manner. The large cavity inside cage, as well favorable donor-acceptor between porphyrin panels guests, enables cage to be an excellent receptor. 1:1 host-guest...
Hydroazaacene dicarboximide derivatives with red to NIR absorptions are designed and synthesized, which exhibit well-defined J-aggregation behaviors in both solution thin films. The absorption emission of an aggregate extend well into the regime (λ(max) = 902 nm), manifesting particularly narrow bandwidth (fwhm 152 cm(-1)) is nearly transparent visible region.
Abstract Two-photon excited near-infrared fluorescence materials have garnered considerable attention because of their superior optical penetration, higher spatial resolution, and lower scattering compared with other materials. Herein, a convenient efficient supramolecular approach is used to synthesize two-photon emissive co-crystalline material. A naphthalenediimide-based triangular macrocycle coronene form selectively two co-crystals. The triangle-shaped co-crystal emits deep-red...
Colored charge-transfer complexes can be formed by the association between electron-rich donor and electron-deficient acceptor molecules, bringing about narrowing of HOMO–LUMO energy gaps so that they become capable harnessing visible light. In an effort to facilitate use these widespread, but nonetheless weak, interactions for light photocatalysis, it is important render strong robust. Herein, we employ a well-known donor–acceptor [2]catenane—formed mechanical interlocking...
Abstract Accurately distinguishing between enantiomeric molecules is a fundamental challenge in the field of chemistry. However, there still significant room for improvement both selectivity (K R ( S ) /K and binding strength most reported macrocyclic chiral receptors to meet demands practical application scenarios. Herein, we synthesized water‐soluble conjugated tubular host—namely, corral[4]BINOL—using 1,1′‐bi‐2‐naphthol (BINOL) derivative as repeating unit. The backbone endows...
Triplet-triplet annihilation-based molecular photon upconversion (TTA-UC) is a photophysical phenomenon that can yield high-energy emitting photons from low-energy incident light. TTA-UC believed to fuse two triplet excitons into singlet exciton through several consecutive energy-conversion processes. When organic aromatic dyes─i.e., sensitizers and annihilators─are used in TTA-UC, intermolecular distances, as well relative orientations between the chromophores, are important an attempt...
The precise recognition and sensing of steroids, a type vital biomolecules, hold immense practical value across various domains. In this study, we introduced corral[4]BINOLs (C[4]BINOLs), pair enantiomeric conjugated deep-cavity hosts, as novel synthetic receptors for binding steroids. Due to the strong hydrophobic effect their deep nonpolar, chiral cavities, two enantiomers C[4]BINOLs demonstrated exceptionally high affinities (up 10
Nanomedicines often rely on noncovalent self-assembly and encapsulation for drug loading delivery. However, challenges such as reproducibility issues due to the multicomponent nature, off-target activation caused by premature release, complex pharmacokinetics arising from assembly dissociation have hindered their clinical translation. In this study, we introduce an innovative design concept termed single molecular nanomedicine (SMNM) based macrocyclic carrier-drug conjugates. Through...
Helicates are a defining element of DNAs and proteins, with functions that critical to variety biological processes. Cyclodextrins promising candidates for forging multiple-stranded helicates well-defined helicity, but lack available tools has precluded the construction artificial helical nanochannels controllable geometry helicity from these widely chiral building blocks. Herein, we disclose family Ag6L2 can be readily assembled α-cyclodextrin-derived ligands through coordination between...
Designing macrocycles with appropriate molecular recognition features that allow for the integration of suitable external stimuli to control host–guest processes is a challenging endeavor which enables containers solubilize, stabilize, and separate chemical entities in an externally controllable manner. Herein, we introduce photo- thermal-responsive elements into semi-rigid tetracationic cyclophane, OPVEx2Box4+, composed oligo(p-phenylenevinylene) pyridinium units biphenylene-bridged...
The host-guest recognition between two macrocycles to form hierarchical non-intertwined ring-in-ring assemblies remains an interesting and challenging target in noncovalent synthesis. Herein, we report the design characterization of a box-in-box assembly on basis radical-pairing interactions rigid diradical dicationic cyclophanes. One striking feature complex is its ability host various 1,4-disubstituted benzene derivatives inside as third component cavity smaller cyclophanes produce Russian...
One ring threaded by two other rings to form a non-intertwined ternary ring-in-rings motif is challenging task in noncovalent synthesis. Constructing multicolor photoluminescence systems with tunable properties also fundamental research goal, which can lead applications multidimensional biological imaging, visual displays, and encryption materials. Herein, we describe the design synthesis of binary ring-in-ring(s) complexes, based on an extended tetracationic cyclophane cucurbit[8]uril. The...
Developing an extremely efficient and highly selective process for gold recovery is urgently desired maintaining a sustainable ecological environment. Herein, we report gold-recovery protocol on the basis of instantaneous assembly between cucurbit[6]uril (CB[6]) [AuX4]− (X = Cl/Br) anions. Upon mixing CB[6] with four gold-bearing salts MAuX4 (M H/K, X in aqueous solutions, yellow or brown coprecipitates form immediately, as result multiple weak [Au–X···H–C] hydrogen-bonding [Au–X···C=O]...
Artificial molecular machines (AMMs) built from mechanically interlocked molecules (MIMs) can use energy ratchets to control the unidirectional motion of their component parts. These are operated by alteration kinetic barriers and thermodynamic wells, which are, in turn, determined switching on off noncovalent interactions. Previously, we have developed artificial pumps (AMPs) capable pumping rings consecutively onto a collecting chain as part dumbbell, leading formation rotaxanes. Here,...
For the most part, enzymes contain one active site wherein they catalyze in a serial manner chemical reactions between substrates both efficiently and rapidly. Imagine if situation could be created within chiral porous crystal containing trillions of sites where can reside vast numbers before being converted parallel into products. Here, we report how it is possible to incorporate 1-anthracenecarboxylate (1-AC-) as substrate γ-cyclodextrin-containing metal-organic framework (CD-MOF-1),...
The exploitation of specific guests which can respond to external stimuli is the main approach for construction stimuli-responsive supramolecular polymers (SPs) based on host-guest interactions. Most functional guests, however, fail manifest stimuli-responses. Herein, a hypoxia-responsive dimeric azocalixarene (D-SAC4A) with outstanding hosting properties was used as macrocyclic building block preparation host SPs. Since azocalixarenes also be compatible an antitumor drug, camptothecin...
Despite the advances in host-guest chemistry, macrocyclic hosts with deep cavities are far from abundant among large number of wholly synthetic described literature. Herein, we describe design and synthesis two new tubular hosts, namely, corral[4]arene corral[5]arene. The former has been isolated characterized as conformational diastereoisomers, one is centrosymmetric other asymmetric. latter, a fivefold symmetrical flexible host, also investigated detail. It composed five...