A5044944734- Supramolecular Self-Assembly in Materials
- Supramolecular Chemistry and Complexes
- Optical Network Technologies
- X-ray Diffraction in Crystallography
- Neural Networks and Reservoir Computing
- Blind Source Separation Techniques
- Crystallization and Solubility Studies
- Molecular Sensors and Ion Detection
- Carbohydrate Chemistry and Synthesis
- Protein Structure and Dynamics
- Carbon dioxide utilization in catalysis
- Alzheimer's disease research and treatments
- Glycosylation and Glycoproteins Research
- Luminescence and Fluorescent Materials
- Metal-Organic Frameworks: Synthesis and Applications
- Chemical Synthesis and Analysis
- Silicone and Siloxane Chemistry
- Nanocluster Synthesis and Applications
- Polyoxometalates: Synthesis and Applications
- biodegradable polymer synthesis and properties
University of South Florida
2020-2024
Jilin Medical University
2018
Jilin University
2010-2018
One ring threaded by two other rings to form a non-intertwined ternary ring-in-rings motif is challenging task in noncovalent synthesis. Constructing multicolor photoluminescence systems with tunable properties also fundamental research goal, which can lead applications multidimensional biological imaging, visual displays, and encryption materials. Herein, we describe the design synthesis of binary ring-in-ring(s) complexes, based on an extended tetracationic cyclophane cucurbit[8]uril. The...
A biomimetic receptor for glucose has been developed with high affinity and selectivity. The was efficiently synthesized in three steps through dynamic imine chemistry followed by imine-to-amide oxidation. features two parallel durene panels, forming a hydrophobic pocket [CH⋅⋅⋅π] interactions, pyridinium residues directing four amide bonds towards the pocket. These not only improve solubility but also provide polarized C-H hydrogen bonding. Experimental data DFT calculations show that these...
Abstract Like other discotic molecules, self‐assembled supramolecular structures of perylene bisimides (PBIs) are commonly limited to columnar or lamellar due their distinct π‐conjugated scaffolds and unique rectangular shape cores. The discovery PBIs with beyond layers columns may expand the scope PBI‐based materials. A series unconventional spherical packing phases in PBIs, including A15 phase, σ dodecagonal quasicrystalline (DQC) body‐centered cubic (BCC) is reported. strategy involving...
In contrast to prevalent strategies which make use of β-sheet mimetics block Aβ fibrillar growth, in this study, we designed a series sulfonyl-γ-AApeptide helices that targeted the crucial α-helix domain Aβ13-26 and stabilized conformation avoid forming neurotoxic oligomeric β-sheets. Biophysical assays such as amyloid kinetics TEM demonstrated oligomerization fibrillation could be greatly prevented even reversed presence sulfonyl-γ-AApeptides sequence-specific dose-dependent manner. The...
It remains a challenging task to synthesize well-defined multi-block copolymers through the controlled/living ring-opening polymerization (ROP) of lactones without transesterification, most common side reaction occurring during copolymerization. A series Al-based complexes with different sidearms were prepared for living ROP such as ε-caprolactone (ε-CL) and δ-valerolactone (δ-VL) in presence BnOH at room temperature (RT), affording medium high molecular weight (MW) linear polyesters Mw up...
The self-assembly of chiral Pd12L24 metal-organic cages (MOCs) based on hydrophobic amino acids, including alanine (Ala), valine (Val), and leucine (Leu), into single-layered hollow spherical blackberry-type structures is triggered by nitrates through counterion-mediated attraction. In addition to nitrates, anionic N-(tert-butoxycarbonyl) (Boc)-protected Ala, Val, Leu were used as counterions during the d-MOCs. Previously, we showed that l-Ala suppresses process d-Pd12Ala24 but has no effect...
Abstract Like other discotic molecules, self‐assembled supramolecular structures of perylene bisimides (PBIs) are commonly limited to columnar or lamellar due their distinct π‐conjugated scaffolds and unique rectangular shape cores. The discovery PBIs with beyond layers columns may expand the scope PBI‐based materials. A series unconventional spherical packing phases in PBIs, including A15 phase, σ dodecagonal quasicrystalline (DQC) body‐centered cubic (BCC) is reported. strategy involving...
The complex distribution of functional groups in carbohydrates, coupled with their strong solvation water, makes them challenging targets for synthetic receptors. Despite extensive research into various molecular frameworks, most carbohydrate receptors have exhibited low affinities, and interactions sugars aqueous environments remain poorly understood. In this work, we present a simple pyridinium-based hydrogen-bonding receptor derived from subtle structural modification well-known...