A5037638631- Liver Disease Diagnosis and Treatment
- Diet, Metabolism, and Disease
- Liver Disease and Transplantation
- Hepatitis C virus research
- Gastric Cancer Management and Outcomes
- Pancreatitis Pathology and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Diseases and Immunity
- Gastrointestinal disorders and treatments
- Alcohol Consumption and Health Effects
- Helicobacter pylori-related gastroenterology studies
- Diet and metabolism studies
- Metabolism, Diabetes, and Cancer
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Esophageal Cancer Research and Treatment
- Gut microbiota and health
- Gallbladder and Bile Duct Disorders
- Childhood Cancer Survivors' Quality of Life
- Adolescent and Pediatric Healthcare
- Folate and B Vitamins Research
- Gastrointestinal Bleeding Diagnosis and Treatment
- Healthcare Systems and Challenges
- Animal Virus Infections Studies
- COVID-19 and healthcare impacts
- Esophageal and GI Pathology
Baylor College of Medicine
2014-2024
Michael E. DeBakey VA Medical Center
2016-2022
Center for Innovation
2019-2022
The University of Texas MD Anderson Cancer Center
2022
There are limited data on the risk of hepatocellular cancer (HCC) in patients with non-alcoholic fatty liver disease (NAFLD). We aimed to estimate incident HCC among NAFLD.We conducted a retrospective cohort study from total 130 facilities Veterans Health Administration. Patients NAFLD diagnosed between January 1, 2004 and December 31, 2008 were included followed until diagnosis, death, or 2015. also identified sex- age-matched control without NAFLD. ascertained all new cases Central Cancer...
Nonalcoholic fatty liver disease (NAFLD) is now the most common condition. Predicting its progression could help clinicians manage and potentially prevent complications. We evaluated independent joint effects of metabolic traits on risk cirrhosis hepatocellular carcinoma (HCC) among patients with NAFLD.We assembled a retrospective cohort NAFLD diagnosed at 130 facilities in Veterans Administration between January 1, 2004, December 31, 2008, follow-up through 2015. performed competing...
In patients with NAFLD, those type 2 diabetes mellitus (DM) have a high risk of progression to HCC. However, the determinants HCC in these remain unclear.
One carbon (1C) metabolism nutrients influence epigenetic regulation and they are supplied by diet synthesized gut microbiota. We examined the association between dietary consumption of methyl donors (methionine, betaine choline) B vitamins (folate, B2, B6, B12) community composition structure colonic mucosa-associated microbiota determined 16S rRNA gene sequencing in 97 biopsies 35 men. used food frequency questionnaire to assess daily nutrients, UPARSE SILVA databases for operational...
The long-term risk of disease for patients with nonalcoholic fatty liver (NAFLD) in the absence elevated enzymes is unclear. We conducted a retrospective cohort study using Corporate Data Warehouse Veterans Health Administration.We classified into three groups: steatosis/normal alanine aminotransferase (ALT), steatosis/elevated ALT, and no ALT. examined incidence rates cirrhosis hepatocellular carcinoma (HCC) cause-specific hazard models to evaluate HCC. identified 3,522 15,419 9,267 mean...