Wenli Li

ORCID: 0000-0002-9006-0634
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Animal Nutrition and Physiology
  • Ruminant Nutrition and Digestive Physiology
  • Genetic and phenotypic traits in livestock
  • Reproductive Physiology in Livestock
  • Cancer-related molecular mechanisms research
  • Genomics and Phylogenetic Studies
  • Gut microbiota and health
  • Genetic Mapping and Diversity in Plants and Animals
  • Meat and Animal Product Quality
  • Molecular Biology Techniques and Applications
  • Digestive system and related health
  • Probiotics and Fermented Foods
  • RNA Research and Splicing
  • Pharmacological Effects of Natural Compounds
  • Plant and fungal interactions
  • Effects of Environmental Stressors on Livestock
  • RNA modifications and cancer
  • Nutrition, Genetics, and Disease
  • Animal health and immunology
  • Moringa oleifera research and applications
  • Genomic variations and chromosomal abnormalities
  • RNA and protein synthesis mechanisms
  • Animal Genetics and Reproduction
  • Cardiac Ischemia and Reperfusion
  • Protein Hydrolysis and Bioactive Peptides

U.S. Dairy Forage Research Center
2018-2025

Agricultural Research Service
2018-2025

United States Department of Agriculture
2023-2024

Air Force Medical University
2024

Qingdao Agricultural University
2009-2023

Renji Hospital
2023

Shanghai Jiao Tong University
2023

Hunan Normal University
2022-2023

Linyi University
2016-2022

Tianjin University
2021

Major advances in selection progress for cattle have been made following the introduction of genomic tools over past 10-12 years. These depend upon Bos taurus reference genome (UMD3.1.1), which was created using now-outdated technologies and is hindered by a variety deficiencies inaccuracies. We present new cattle, ARS-UCD1.2, based on same animal as original to facilitate transfer interpretation results obtained from earlier version, but applying combination modern de novo assembly increase...

10.1093/gigascience/giaa021 article EN cc-by GigaScience 2020-03-01

Inserting Introns Introns—noncoding regions that interrupt coding gene sequences—are widespread throughout eukaryotic genomes, but intron gains and losses within among species have been assumed to be rare. However, W. Li et al. (p. 1260 ) suggest insertions can relatively frequent a population or species. By examining polymorphisms genomes of different accessions Daphnia pulpex (the water flea), comparisons the genus , several instances recent were observed, which appear occurred multiple...

10.1126/science.1179302 article EN Science 2009-11-27

Whole transcriptome sequencing (RNA-seq) represents a powerful approach for whole gene expression analysis. However, RNA-seq carries few limitations, e.g., the requirement of significant amount input RNA and complications led by non-specific mapping short reads. The Ion AmpliSeq™ Transcriptome Human Gene Expression Kit (AmpliSeq) was recently introduced Life Technologies as whole-transcriptome, targeted quantification kit to overcome these limitations RNA-seq. To assess performance this new...

10.1186/s12864-015-2270-1 article EN cc-by BMC Genomics 2015-12-01

Gentiana section Cruciata is widely distributed across Eurasia at high altitudes, and some species in this are used as traditional Chinese medicine. Accurate identification of these important for their utilization conservation. Due to similar morphological chemical characteristics, correct discrimination still remains problematic. Here, we sequenced three complete chloroplast (cp) genomes (G. dahurica, G. siphonantha officinalis). We further compared them with the previously published...

10.3390/ijms19071962 article EN International Journal of Molecular Sciences 2018-07-05

Abstract Many common management practices used to raise dairy calves while on milk and during weaning can cause rumen acidosis. Ruminal pH has long been identify ruminal However, few attempts were undertaken understand the role of prolonged acidosis microbial community or host health in young after weaning. Thus, molecular changes associated with post are largely unknown. In this study, we induced by feeding a highly processed, starch-rich diet starting from one week age through 16 weeks....

10.1038/s41598-019-40375-2 article EN cc-by Scientific Reports 2019-03-18

Euphrasia (Orobanchaceae) is a genus which widely distributed in temperate regions of the southern and northern hemisphere. The taxonomy still controversial due to similarity morphological characters lack genomic resources. Here, we present first complete chloroplast (cp) genome this taxonomically challenging genus. cp regelii consists 153,026 bp, including large single-copy region (83,893 bp), small (15,801 bp) two inverted repeats (26,666 bp). There are 105 unique genes, 71 protein-coding...

10.3389/fgene.2019.00444 article EN cc-by Frontiers in Genetics 2019-05-14

The purpose of this study was to evaluate the effects nicotinic acid (NA) supplementation on meat quality, carcass characteristics, lipid metabolism, and tibia parameters in Wulong geese. A total 360 twenty-nine-day-old geese were randomly divided into 6 treatments, each treatment included pens with 10 birds per pen. Birds fed a basal diet supplemented 0, 20, 40, 60, 80, or 100 mg/kg NA for 12 wk. Dietary linearly decreased L* value increased pH water-holding capacity breast muscle (P <...

10.1016/j.psj.2021.101430 article EN cc-by-nc-nd Poultry Science 2021-08-14

Abstract Antibiotics are frequently used in food production animals to control disease and improve productivity, but this promotes the development of antimicrobial resistance (AMR) subsequent broader spread AMR bacteria throughout chain, endangering well‐being health both humans. In humans, gut microbiome harbors a diverse range bacteria, known as resistome. To effectively mitigate requires first determining expression abundance AMR‐related genes Currently, such knowledge regard is largely...

10.1002/cpz1.70116 article EN Current Protocols 2025-03-01

Abstract In mammals, microbial colonization of the digestive tract (GIT) occurs right after birth by several bacterial phyla. Numerous human and mouse studies have reported importance early gut inhabitants on host health. However, few attempts been undertaken to directly interrogate role gut/rumen GIT development or health in neonatal ruminants through artificial manipulation rumen microbiome. Thus, molecular changes associated with are largely unknown cattle. this study, we dosed young...

10.1038/s41598-018-37033-4 article EN cc-by Scientific Reports 2019-01-28

This experiment was conducted to investigate the effects of manganese (Mn) and Bacillus subtilis (BS) on production performance, egg quality, antioxidant capacity, gut microbiota breeding geese during laying period. A total 120 forty-six-week-old (Wulong) were randomly assigned 1 6 treatment diets formulated supply 10, 20, 30 mg/kg Mn with 5 × 10

10.1016/j.psj.2020.08.012 article EN cc-by-nc-nd Poultry Science 2020-08-26

This study investigated the effects of dietary arginine supplementation on production performance, serum biochemicals, antioxidant capacity, and immunity laying Wulong geese. A total 150 geese (34-wk old) with similar body weights were randomly divided into 6 groups 5 replicates each (1 male 4 female). The in control group fed a corn-rapeseed meal basal diet, treatment diet supplemented 0.1, 0.2, 0.3, 0.4, 0.5% arginine. experiment lasted for 17 wk. Our results showed that increased egg rate...

10.1016/j.psj.2023.102727 article EN cc-by-nc-nd Poultry Science 2023-04-14

As one of the few known species in an active phase intron proliferation, microcrustacean Daphnia pulex is especially attractive system for interrogating gain and loss introns natural populations. In this study, we used a comparative population-genomic approach to identify characterize 90 recently gained species. Molecular clock analyses indicate that these arose between 3.9 × 10(5) 1.45 10(4) years ago, with spike proliferation approximately 5.2 1.22 ago. Parallel gains at homologous...

10.1093/gbe/evu174 article EN cc-by-nc Genome Biology and Evolution 2014-08-14

Introduction With the goal to maximize intake of high-fermentable diet needed meet energy needs during weaning period, calves are at risk for ruminal acidosis. Using from previously established model feed-induced, acidosis in young calves, we aimed investigate changes rumen epimural transcriptome and its microbial metatranscriptome (8-week) post-weaning (17-week) canulated (first occurred 3 weeks age) Holstein bull with feed-induced subacute Methods Eight were randomly assigned...

10.3389/fvets.2024.1328539 article EN cc-by Frontiers in Veterinary Science 2024-02-21

A 3 × 2 factorial arrangement of treatments was conducted to investigate the effects iron (Fe, 40, 60, and 80 mg/kg) Bacillus subtilis (2.5 109 5.0 CFU/kg) supplementation on reproductive performance, egg quality, nutrient digestibility, hormone levels, antioxidant indices, hematological parameters in breeder geese. total one hundredtwenty 46-week-old Wulong geese were randomly assigned 1 6 dietary with 4 replicates per treatment 5 replicate for 10 wk following adaption. Dietary Fe increased...

10.1016/j.psj.2020.06.077 article EN cc-by-nc-nd Poultry Science 2020-08-08

Red clover (Trifolium pratense L.) is a diploid, naturally cross-pollinated, cool-season species. As perennial forage legume, red mostly cultivated in temperate regions worldwide. Being non-model crop species, genomic resources for have been underdeveloped. Thus far, analysis used has mainly relied on simple sequence repeat (SSR) markers. However, SSR markers are sparse the genome and it often difficult to unambiguously map them using short reads generated by next generation sequencing...

10.3389/fpls.2019.01257 article EN cc-by Frontiers in Plant Science 2019-10-23

The effects of zinc (Zn) and Bacillus subtilis (B. subtilis) on reproductive performance, egg quality, nutrient digestion, intestine morphology, antioxidant capacity were explored in geese breeders. Geese breeders (n = 120, 46-wk age) randomly assigned into 6 groups with 4 replicates 5 birds each (1 male female). Breeders fed diets 2 levels B. (2.5 × 109 CFU/kg) crossed three Zn (25, 45, 65 mg/kg) for duration 10-wk. results showed that the laying rate (P < 0.05), fertility 0.01),...

10.1016/j.psj.2021.101677 article EN cc-by-nc-nd Poultry Science 2021-12-24

Abstract The pulsatile pattern of prostaglandin F2alpha (PGF) secretion during spontaneous luteolysis is well documented, with multiple pulses exogenous PGF necessary to induce regression using physiologic concentrations PGF. However, regression, the earliest are small and not associated detectable changes in circulating progesterone (P4), bringing into question what, if any, role these early, subluteolytic have regression. To investigate effect pulses, luteal biopsies were collected...

10.1093/biolre/ioab123 article EN Biology of Reproduction 2021-06-25
Coming Soon ...