A5025854451- Neonatal and Maternal Infections
- Immune Response and Inflammation
- Streptococcal Infections and Treatments
- Sepsis Diagnosis and Treatment
- Neonatal Respiratory Health Research
- Infectious Diseases and Tuberculosis
- Antibiotic Resistance in Bacteria
- Inflammasome and immune disorders
- Viral Infections and Vectors
- Infant Nutrition and Health
- SARS-CoV-2 and COVID-19 Research
- Bacterial Identification and Susceptibility Testing
- Congenital Diaphragmatic Hernia Studies
- Pediatric Hepatobiliary Diseases and Treatments
- Clostridium difficile and Clostridium perfringens research
- Metabolism and Genetic Disorders
- COVID-19 epidemiological studies
- Liver Diseases and Immunity
- Autoimmune and Inflammatory Disorders Research
- Tuberculosis Research and Epidemiology
- Fire effects on ecosystems
- Diphtheria, Corynebacterium, and Tetanus
- Pneumocystis jirovecii pneumonia detection and treatment
- COVID-19 and Mental Health
- Immunodeficiency and Autoimmune Disorders
Kazan State Medical University
2014-2024
Introduction:Klebsiella pneumoniae is one of the most important infectious agents in neonates. There are "classic" and hypervirulent strains K. pneumoniae. The non-virulent strain pneumoniae, producing extended-spectrum beta-lactamases (ESBLs), associated with nosocomial infections. Hypervirulent invasive infections previously healthy adult people, them exhibit antimicrobial susceptibility. role virulent (including hv-KP) neonatal unknown. aim study was assessment impact virulence factors...
Klebsiella pneumoniae is one of the most important infectious agents among neonates. This pathogen has a potential to develop an increased antimicrobial resistance and virulence. The classic nonvirulent strain K. pneumoniae, producing extended-spectrum beta-lactamases (ESBL), associated with nosocomial infection mainly in preterm Hypervirulent strains are invasive previously healthy ambulatory patients, them exhibit susceptibility. During last few years, several cases diseases caused by...
One of the common childhood illnesses is reactive arthritis, which develops during or soon after an infection. Purpose. The aim study was to etiology, clinical and laboratory manifestations arthritis in children. Material methods. included 37 children with aged 1 year 10 months 15 years who were hospitalized at Kazan City Children’s Hospital № 1. Results. Reactive diagnosed 26 children, juvenile idiopathic 11. In 20 patients, manifested itself as monoarthritis predominant damage hip knee...
BACKGROUND: Lymphopenia in patients with coronavirus infection COVID-19 is associated the risk of developing severe forms and unfavorable outcome. One reasons for development lymphopenia apoptosis. AIM: Evaluation severity peripheral blood lymphocytes' apoptosis moderate COVID-19. MATERIAL AND METHODS: A total 42 aged 37 to 90 years were examined. They hospitalized at Republican Clinical Infectious Diseases Hospital named after Professor A.F. Agafonov, Kazan, from October 24, 2021 March 1,...
миляуша ильдуСовна иСмагилова, врач-педиатр изоляционно-диагностического отделения Детской республиканской клинической больницы
Background. Despite the obvious successes of world community in fight against spread SARS-CoV-2, attempts to create new drugs that are active COVID-19 pathogen do not stop. In parallel, a targeted search for prevention opportunities is being carried out. Vaccination does protect 100% possible infection, but significantly reduces risk developing severe forms COVID-19, need hospitalization and death. Aim. Describe course patients previously vaccinated this infection. Material methods. On basis...
We studied the lymphocyte apoptosis in 15 infants with late neonatal sepsis, whereas 8 of them (53.3%) were considered as a preterm infants. Etiology sepsis was identified 4 cases (26.7%): 1 case each, cause disease Klebsiella pneumoniae, Pseudomonas koreenses, Candida and St. agalactae. Control group consisted 5 healthy newborns. Apoptosis analysis conducted by measuring amount hypodiploid cells using propidium iodide (Sigma Aldrich) DNA staining procedure flow cytometry (FACsCanto II,...
Реферат.В статье представлен литературный обзор по механизмам противоинфекционной защиты у детей периода новорожденности с акцентом на врожденный иммунитет.Рассмотрены современные принципы раз-
Human milk sIgA molecules contain various combination of 17.different antigen
Aim. To determine the diagnostic significance of antibodies to Hantavirus in patients with hemorrhagic fever renal syndrome, depending on period and severity course disease. Methods. Studied was content specific (immunoglobulins G) hantaviruses blood serum rapidly precipitating slowly circulating immune complexes by enzyme immunoassay using a test system «Hantagnost» modification. were 226 syndrome (24 mild form, 105 moderate 97 severe form disease) febrile, oliguric polyuric periods....
Aim. To assess of adaptive immunity the duodenal mucosa in neonates with sepsis.
 Methods. A study biopsy specimens obtained during duodenoscopy from who had signs suspected ulcerative lesions digestive tract. Five them were infants clinical and laboratory neonatal sepsis (NS), two without (comparison group). Immunohistochemical staining was performed using Novolink Polymer Detection System imaging system commercial antibodies to CD4, CD8, CD20 Bcl-2, CSAII Biotin-free Tyramide Signal...
Lemierre's syndrome is a clinical variant of sepsis characterized by combination an infectious process in the oropharynx with thrombosis internal jugular vein and metastatic septic foci. Currently, rare pathology, almost forgotten disease. The article describes case syndrome, which course acute tonsillopharyngitis 20-year-old female patient was complicated left metastasis foci lungs. accompanied systemic inflammatory reaction thrombocytopenia. microorganism from blood not isolated. In crops...