A5002204000- Multiple Myeloma Research and Treatments
- Pneumocystis jirovecii pneumonia detection and treatment
- HIV/AIDS Research and Interventions
- Clostridium difficile and Clostridium perfringens research
- Infectious Diseases and Tuberculosis
- Neutropenia and Cancer Infections
- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- Mycobacterium research and diagnosis
- Vascular Anomalies and Treatments
- Chronic Myeloid Leukemia Treatments
- Fungal Infections and Studies
- Uterine Myomas and Treatments
- Chronic Lymphocytic Leukemia Research
- Bacterial Identification and Susceptibility Testing
- Esophageal and GI Pathology
- Antifungal resistance and susceptibility
- Otolaryngology and Infectious Diseases
- Renal Transplantation Outcomes and Treatments
- Pneumothorax, Barotrauma, Emphysema
- Protein Degradation and Inhibitors
- Polyomavirus and related diseases
- Obstructive Sleep Apnea Research
- Hemophilia Treatment and Research
- Tuberous Sclerosis Complex Research
Albert Einstein College of Medicine
2022-2025
Montefiore Medical Center
2022-2025
University of Utah
2023-2025
University of Michigan
2024
Einstein Medical Center Philadelphia
2019-2021
Einstein Healthcare Network
2019
Brookdale University Hospital and Medical Center
2015
Abstract Background Chronic Trypanosoma cruzi infection can be asymptomatic, but T.cruzi reactivate and cause disease among transplant recipients following immunosuppression. Prior to it is recommended perform 2-step testing candidates at high risk of exposure, defined as patients who were born or had prolonged residence in Mexico, Central, South America. We reviewed our institution identify the frequency testing, percentage with positive whether was being performed appropriate high-risk...
ABSTRACT Background People living with HIV have a higher waitlist mortality and decreased access to transplants. The enactment of the Organ Policy Equity Act (HOPE Act) in 2013 was step toward increasing donor population. However, utilization organs through act has been less than initially anticipated, both nationally at our center. Methods To improve acceptance abdominal from donors positive tests (D+) for recipients (R+), we implemented multidisciplinary educational intervention center...
The field of transplant infectious diseases is rapidly evolving, presenting a challenge for clinical practice and trainee education. Here we describe the construction transplantid.net, free online library, crowdsourced continuously updated dual purpose point-of-care evidence-based management teaching.
Hemophagocytic lymphohistiocytosis (HLH) is a rare condition characterized by an overwhelming inflammatory cascade activation which often associated with rapid progression and high mortality. It may be familial underlying genetic mutation or triggered infection, malignancy, autoimmune disease. Disseminated histoplasmosis caused histoplasma capsulatum granulomatous fungal disease seen typically in immunocompromised patients varied clinical manifestations requires long-term antifungal therapy....
The COVID-19 pandemic is associated with a significant increase in the incidence of invasive mycosis, including pulmonary aspergillosis, mucormycosis, and candidiasis. Fungal empyema thoracis (FET) an uncommon clinical presentation fungal disease (IFD) mortality. Here, we describe first report patient post-COVID-19 multifocal necrotizing pneumonia complicated by polymicrobial that included Candida glabrata. empyemas represent another manifestation COVID-19-associated opportunistic infection,...
Abstract Advancement in solid organ transplantation and hematopoietic stem cell transplant continues to improve the health outcomes of patients widens number eligible who can benefit from medical progress. Preserving effectiveness antimicrobials remains crucial, as otherwise surgeries would be unsafe due surgical site infections, risk sepsis with neutropenia preclude transplant. In this review, we provide updates on three previously discussed stewardship challenges: febrile neutropenia,...
Plasma cell leukemia (PCL) is a rare and aggressive variant of myeloma has poor prognosis. It needs prompt recognition in order to institute timely treatment. Given its relatively low incidence, it an evolving area research as well. This case report describes patient with PCL the setting previously treated myeloma. The also reviews clinicopathologic, cytogenetic, immunophenotypic characteristics management.
In this case, a 76-year-old female presented with 3-4 days of fever no other localizing signs. Notably, she had an untreated Fusobacterium bacteraemia approximately 8 weeks prior to admission. She underwent abdominal imaging which demonstrated liver abscess and percutaneous drainage the same. Blood pus cultures both grew nucleatum, is unusual organism be associated abscess, especially in immunocompetent host risk factors for condition. Interestingly, patient did not have any history dental...
<ns5:p>A 58-year-old man presented with recurrence of chronic myeloid leukemia (CML) after complete molecular remission in the setting non-compliance imatinib. He was restarted on imatinib and also noted to have IgG kappa monoclonal gammopathy undetermined significance (MGUS). The patient re-achieved resumption imatinib, but his MGUS progressed smoldering myeloma he eventually diagnosed multiple (MM) initiated treatment for MM thalidomide, bortezomib dexamethasone. has responded well...
Heavy menstrual bleeding (HMB) is common, and 20-30% of patients presenting with HMB are diagnosed an inherited disorder (IBD). Despite the frequent association disorders, specific learning objectives on this topic lacking for Obstetrics Gynecology (OBGYN) residents.
<ns4:p>A 58-year-old man presented with recurrence of chronic myeloid leukemia (CML) after complete molecular remission in the setting non-compliance imatinib. He was restarted on imatinib and also noted to have IgG kappa monoclonal gammopathy undetermined significance (MGUS). The patient re-achieved resumption imatinib, but his MGUS progressed smoldering myeloma he eventually diagnosed multiple (MM) initiated treatment for MM thalidomide, bortezomib dexamethasone. has responded well...
The presence of air in the mediastinal cavity (i.e., pneumomediastinum) is an uncommon condition. It usually precipitated by event such as penetrating trauma, barotrauma or increased intrathoracic pressure caused severe vomiting coughing. We present case a 32-year-old man who developed pneumomediastinum result heavy weightlifting.
This is a case of 27-year-old primigravida with monochorionic diamniotic twin gestation who was admitted to the hospital for induction labour. Her postpartum course complicated by microangiopathic haemolytic anemia (MAHA). The etiology MAHA initially thought be secondary pre-eclampsia and vitamin B12/folate deficiency. However, she had persistent further workup demonstrated that left renal cell carcinoma (RCC) perinephric haemorrhage consistent Wunderlich syndrome. intriguing because its...
Abstract Background Hospital-onset Clostridioides difficile infection (HO-CDI) is a nosocomial that adversely impacts length of stay, morbidity, and mortality, contributes to 6 billion dollars in U.S. healthcare expenditures. Our aim was identify categorize antibiotic prescribing patterns amongst patients with HO-CDI at our institution design targeted interventions based on these findings. Methods A physician-assigned review electronic medical records for all laboratory-confirmed cases...
Abstract Background Inappropriate vancomycin use in patients with febrile neutropenia (FN) can contribute to emergence of resistant organisms, acute kidney injury, and infusion related adverse effects. Methicillin Staphylococcus aureus (MRSA) nares Polymerase Chain Reaction (PCR) testing has a high negative predictive value for invasive MRSA infections therefore, offers rapid tool help avoid or de-escalate anti-MRSA therapy. In this study, we aimed assess the impact PCR on utilization...
Oesophageal varices are a dilated submucosal venous plexus in the lower third of oesophagus which result from increased pressure portal system. The system is connected to systemic circulation specific locations referred as sites portosystemic anastomosis. An increase therefore reflected at these anastomotic sites, causing manifestations such oesophageal varices, rectal caput medusae and splenorenal shunts. Varices do not cause symptoms until they leak or rupture this main complication...
Abstract Background The HIV Organ Policy Equity Act (HOPE Act) was enacted in the US on November 21, 2013. patients have a higher waitlist mortality and decreased access to transplant compared negative controls. major step towards increasing donor pool, but utilization of organs through act has been less than initially anticipated.. Our own institution performed only one D+/R+ first four years trial despite significant number HIV+ waitlist. TableFigure summarizing perceived barriers targeted...