- Pancreatic and Hepatic Oncology Research
- Pancreatitis Pathology and Treatment
- Gallbladder and Bile Duct Disorders
- Esophageal and GI Pathology
- Gastric Cancer Management and Outcomes
- Pediatric Hepatobiliary Diseases and Treatments
- Gastrointestinal Tumor Research and Treatment
- Gastrointestinal disorders and treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Esophageal Cancer Research and Treatment
- Metastasis and carcinoma case studies
- Liver Disease Diagnosis and Treatment
- Gastroesophageal reflux and treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease and Transplantation
- Monoclonal and Polyclonal Antibodies Research
- Glycosylation and Glycoproteins Research
- Gastrointestinal Bleeding Diagnosis and Treatment
- Infectious Diseases and Tuberculosis
- Eosinophilic Esophagitis
- Cancer Diagnosis and Treatment
- Galectins and Cancer Biology
- Eosinophilic Disorders and Syndromes
- Biliary and Gastrointestinal Fistulas
- Acupuncture Treatment Research Studies
Ohta Nishinouchi Hospital
2024
Dokkyo Medical University
2020-2023
Fukushima Medical University
1985-2023
Gunma University Hospital
2017-2021
Gunma University
2016-2020
Hamamatsu Medical Center
2018
Medical & Biological Laboratories (Japan)
2014
RIKEN
2013-2014
Juntendo University
2013
National Institute of Advanced Industrial Science and Technology
2013
It is difficult to perform endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) of small gastrointestinal (GI) subepithelial lesions (SELs) approximately 10 mm in diameter. This study was undertaken evaluate the feasibility, safety, and diagnostic ability EUS-FNA with a forward-viewing curved linear-array echoendoscope (FVCLA-ES) that has cap for SELs.The enrolled 8 patients who had upper GI SELs To fix during FNA, device attached scope tip.The mean (standard deviation [SD])...
We report on a 75-year-old man who was admitted due to pancreatic cystic lesion accompanied by solid mass with liver metastasis. Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) performed the mass, and pathological findings revealed be an adenocarcinoma diagnosed as intraductal papillary mucinous carcinoma (IPMC). Approximately 3 months after, subepithelial appeared in posterior gastric wall where EUS-FNA had been performed. again, which that IPMC pathology similar original...
The purpose of the present study is to report our experience endoscopic ultrasound‐guided coil deployment with sclerotherapy (EUS‐CS) for isolated gastric varices (IGV) through a case series. Eight consecutive patients who had risky IGV were prospectively enrolled. EUS‐CS was performed according following procedures: (i) several coils first deployed in under EUS guidance; (ii) contrast medium subsequently injected without removing needle; (iii) if infused stayed and feeding vein, sclerosant...
The Rosemont classification (RC) was developed as a consensus-based standard for the diagnosis of chronic pancreatitis (CP) by endoscopic ultrasonography (EUS), however, it is more complicated than conventional scoring system. We have noticed that in early stages CP, not unusual to observe pancreas with abnormal appearance coexisting areas normal parenchyma. aim this study investigate validity "normal" and evaluate usefulness modified diagnostic criteria comparison traditional EUS RC.One...
Background and study aims: Biliary stent dysfunction is mainly caused by biliary sludge that forms as a result of bacterial adherence subsequent biofilm formation on the inner surface stent. Silver ions arewell known to have excellent antimicrobial activity against wide range microorganisms. In this study, we designed constructed silver-coated plastic (PS) investigated whether silver coating prevented through use electron microscopy. Material methods: The polyurethane PS with/without were...
In 2009, diagnostic criteria for early chronic pancreatitis (DCECP2009) were proposed by the Japan Pancreas Society. This study aimed to evaluate interobserver reliability (IOR) of endoscopic ultrasound (EUS) diagnosis (ECP) between DCECP2009 and 2019 ECP (DCECP2019) assess validity revision from perspective EUS findings. Among patients who underwent a detailed observation pancreas at our institution January 2018 March 2019, images 97 extracted. Images reviewed 12 gastrointestinal endoscopy...
Introduction: Wire-guided cannulation (WGC) during endoscopic retrograde cholangiopancreatography (ERCP) is a selective biliary technique aimed at improving the successful rate and reducing of post-ERCP pancreatitis (PEP) incidence. This study to evaluate effectiveness angled-tip guidewires (AGW) vs. straight-tip (SGW) for via WGC by trainee. Methods: We conducted prospective, single-center, open-labeled, randomized, controlled trial. Fifty-seven patients were enrolled in this assigned...
The aim of this study is to clarify the relation between incision size for endoscopic sphincterotomy (EST) and common bile duct stone (CBDS) recurrence.Patients who underwent elective treatment CBDS January 2013 December 2017 were enrolled, excluding those met exclusion criteria. clinical characteristics investigated using propensity score matching analysis.A total 243 patients investigated. Propensity scores calculated multinomial logistic regression with five relevant variables (age,...
According to the mechanistic definition, history of acute pancreatitis (AP) is a risk factor for chronic (CP). However, etiology and severity previous AP involved in progression CP have not been clarified. Here, we investigated factors patients with past-history AP.Sixty-four who were followed-up at least two years our institution between April 2009 March 2017 enrolled. The multivariate analysis was performed based on extracted by univariate analysis.Among 64 patients, 13 (20.3%) progressed...
Journal Article Lectin-dependent inhibition of antigen–antibody reaction: application for measuring α2,6-sialylated glycoforms transferrin Get access Kyoka Hoshi, Hoshi 1Department Biochemistry, Fukushima Medical University School Medicine, 1 Hikarigaoka, Fukushima-shi, 960-1295; 2Structural Glycobiology Team, Systems Research Group, Chemical Biology Department, RIKEN, 2-1 Hirosawa, Wako-shi, Saitama 351-0198; 3Department Neurosurgery, Juntendo 2-1-1 Hongou, Bunkyou-ku, Tokyo 113-8421;...
<b>Background and study aims: </b>Trainees are required to learn EUS-FNA using a model before working with patient. The aim of the current was validate new training developed for EUS-FNA. <b>Patients methods:</b> Several fresh chicken tenderloins were embedded as target lesions in submucosal layer an isolated porcine stomach. stomach fixed plate nails, placed tub filled water. primary endpoint feasibility newly training, evaluated follows: 1) visualization lesion blinding location; 2)...
Ultrasound speed (USS) correction improves image quality by estimating the optimal USS correcting deviation from a predetermined USS. This study assessed differences between chronic pancreatitis (CP), early CP (ECP), and normal pancreas when using endoscopic ultrasound (EUS). The usefulness of measuring was evaluated for patients with CP, including stage patients.This enrolled 116 consecutive whom measured an EUS system. principle is generation B-mode changing in all ranges while delay...
Success rates of balloon enteroscopy-assisted endoscopic retrograde cholangiopancreatography (BE-ERCP) for patients with a reconstructed intestinal tract after surgical procedures are unsatisfactory. We retrospectively investigated the factors associated unsuccessful BE-ERCP. Ninety-one who had gastrectomy or choledochojejunostomy were enrolled. Age, sex, operative method, malignancy, endoscope type, endoscopist’s skill, emergency procedure, and time required to reach papilla/anastomosis...
Recently, ProCore™ was developed as an endoscopy ultrasound (EUS)-guided histology needle designed to address several current limitations of EUS-guided fine-needle aspiration (FNA). Nevertheless, tissue yield with the is not consistent. No standard technique has been established. This experimental study conducted ascertain best maneuver when using ProCore™.We performed and biopsy (FNAB) a 22-gauge (G) chicken tenderloin liver. Six methods were used, two movement techniques (natural speed...
In recent years, balloon enteroscopy-assisted endoscopic retrograde cholangiopancreatography (BA-ERCP) has been performed for biliary pancreatic procedures postoperative reconstruction of the intestinal tract. BA-ERCP, especially in cases after Roux-en-Y anastomosis, it is often difficult to identify afferent limb. Several methods have reported so far [1] [2] [3]. Herein we report a new method that can discriminate more objectively.
We previously found that a lectin, Sambucus sieboldiana agglutinin (SSA), bound to α2,6-sialylated glycan epitopes on transferrin and inhibited anti-transferrin antibody binding the antigen in ELISA (SSA inhibition). Here we report SSA inhibition is applicable immunohistochemistry, localizing liver. Immunohistochemistry using polyclonal revealed was detected hepatocytes near interlobular veins. Addition of lectin markedly attenuated staining. Sialidase treatment liver section abolished...
A 71-year-old man in whom a gastric submucosal lesion was found incidentally referred to our hospital for detailed examination. Esophagastroduodenoscopy showed the body of stomach. Endoscopic ultrasound revealed 15-mm hypoechoic round mass with calcifications arising from muscular layer. Confusing diagnosis, it resembled gastrointestinal mesenchymal tumor. Subsequently, endoscopic ultrasound-guided fine-needle aspiration conducted definitive diagnosis. Pathologic analysis granuloma. Because...
Esophageal adenocarcinoma (EAC) derived from long-segment Barrett's esophagus (LSBE) is extremely rare in Asia. LSBE-related EAC often difficult to diagnose the horizontal extent. If tumor has spread throughout LSBE, whole circumferential endoscopic submucosal dissection (ESD) should be performed, which complete safely. Additionally, ESD can bring refractory postoperative stenosis. We hereby report a case of involving circumference achieving removal without complications.An 85-year-old man...