A5020739056- Breast Lesions and Carcinomas
- Mass Spectrometry Techniques and Applications
- Advanced Proteomics Techniques and Applications
- Cleft Lip and Palate Research
- Male Breast Health Studies
- Metabolomics and Mass Spectrometry Studies
- Bone fractures and treatments
- Orthopedic Surgery and Rehabilitation
- Facial Trauma and Fracture Management
- Neonatal Respiratory Health Research
- Airway Management and Intubation Techniques
- Breast Cancer Treatment Studies
- Lymphatic System and Diseases
- Vibrio bacteria research studies
- Bacterial biofilms and quorum sensing
- Breast Implant and Reconstruction
- Reconstructive Surgery and Microvascular Techniques
- Machine Learning in Bioinformatics
- Congenital Anomalies and Fetal Surgery
- Intensive Care Unit Cognitive Disorders
- Craniofacial Disorders and Treatments
- Antibiotic Resistance in Bacteria
- Traumatic Ocular and Foreign Body Injuries
- Anesthesia and Sedative Agents
- Tracheal and airway disorders
Technical University of Munich
2022-2025
IONICS Mass Spectrometry (Canada)
2025
Mansoura University
2012-2024
Abstract Machine learning (ML) and deep (DL) models for peptide property prediction such as Prosit have enabled the creation of high quality in silico reference libraries. These libraries are used various applications, ranging from data‐independent acquisition (DIA) data analysis to data‐driven rescoring search engine results. Here, we present Oktoberfest, an open source Python package our spectral library generation pipeline originally only available online via ProteomicsDB. Oktoberfest is...
The prediction of fragment ion intensities and retention time peptides has gained significant attention over the past few years. However, progress shown in accurate such properties focused primarily on unlabeled peptides. Tandem mass tags (TMT) are chemical peptide labels that coupled to free amine groups usually after protein digestion enable multiplexed analysis multiple samples bottom-up spectrometry. It is a standard workflow proteomics ranging from single-cell high-throughput...
In this study, we evaluate the versatility of smartphone thermal imaging technology as a valuable intraoperative modality in different stages perforator flap surgery aiming to minimize complications and achieve best postoperative outcome.Thermography was performed 20 flaps patients at surgical three ways identify most dominant perforator: first, by measuring surface temperature skin; second, using dynamic infrared thermography technique; third, assessing perfusion pattern when supplied each...
Identifying detectable peptides, known as flyers, is key in mass spectrometry-based proteomics. Peptide detectability strongly related to peptide sequences and their resulting physicochemical properties. Moreover, the high variability MS data challenges development of a generic model for prediction, underlining need customizable tools. We present Pfly, deep learning developed predict based solely on sequence. Pfly versatile reliable state-of-the-art tool, offering performance, accessibility,...
BackgroundBurned patients exhibit resistant response to nondepolarizing muscle relaxants. This study was designed investigate the efficacy of high dose atracurium (3 and 4 times ED95) with without application priming principle on intubating conditions onset in burned patients.MethodsASA physical status I II undergoing burn related surgery, were randomly allocated into one four groups 20 each. Group received 1 ml placebo followed 3 min later by 0.75 mg/kg, group 0.04 mg/kg as 0.71 III IV 0.96...
Background: Gynecomastia is an abnormal and benignenlargement of male breast tissue. It occurs as a result animbalance between estrogen androgen levels that may bedue to physiological or pathological cause. Multiple surgicalapproaches have been recommended manage this problem.It widely accepted liposuction solely when combinedwith subcutaneous mastectomy effective for the managementof low intermediate grades gynecomastia. However,liposuction along with gives unsatisfactoryresults in high...
Management of severe velopharyngeal dysfunction is best performed by a multispecialty team. This team could include speech-language pathologist, otolaryngologist, prosthodontist, and plastic surgeon. The most commonly surgical procedures in complicated cases with scarred soft palate are sphincter pharyngoplasty pharyngeal flaps. In this study, multidisciplinary approach was applied for proper assessment intervention using insufficiency after cleft repair. Twenty patients underwent...
Type III Secretion System (Exoenzymes) as a Virulence Determinant in Pseudomonas aeruginosa Isolated from Burn Patients Mansoura University Hospitals, Egypt
Background: Although different bone graft materials have been suggested in the literatures for alveolar cleft reconstruction including autogenous, allogenic, xenogenic, and alloplastic grafts, Autogenous either from iliac crest or tibial plateau remains gold standard against which other are evaluated.However, procedure is invasive associated with a potential risk of early complications such as bleeding, pain, infection, fracture and/or late chronic scarring, paresthesia gait...
Aim: Orbital trauma is considered one of the most commonmaxillofacial traumas with functional and cosmetic impactto eye globe. The main objective to establish a roadmap for management orbital floor fractures.Patients Methods: One hundred seventy-threepatients were selected from database Mansoura UniversityHospitals fractures who treatedat Department Plastic & Reconstructive Surgery Departmentover past 4 years. Cases retrospectively reviewedby preoperative clinical findings, management,...
Gynecomastia is the commonest clinical breast conditionin males. This study had described surgical approaches donefor different grades of gynecomastia. Eighty seven cases hadbeen operated for gynecomastia were analyzed in this studyfrom 2016 to 2019. One hundred and sixty three breasts, theclinical data regarding patients' satisfaction, size, breastssymmetry, shape symmetry nipple areola complexand their scars evaluated. All satisfiedabout results surgery; however patients with grade...
Major burn injury management represents a difficult issueespecially in developing countries. Skin auto-grafts is the bestnatural skin substitute for replacing burned but its rarityin major burns patients stand as an obstacle to be used. Earlydeep wounds excision and coverage of morethan 30% body surface area main strategy woundmanagement massive yet with absence skinbanks (skin allo-grafts) expensive artificial substitute'scoverage raw by these methods not applicablein Egypt. In this study,...