Shazia Kousar

ORCID: 0000-0002-9110-4897
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About
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Research Areas
  • Ethnobotanical and Medicinal Plants Studies
  • Plant Ecology and Taxonomy Studies
  • Essential Oils and Antimicrobial Activity
  • Catalytic C–H Functionalization Methods
  • Catalytic Cross-Coupling Reactions
  • Catalytic Alkyne Reactions
  • Sulfur-Based Synthesis Techniques
  • Click Chemistry and Applications
  • Phenothiazines and Benzothiazines Synthesis and Activities
  • Natural Antidiabetic Agents Studies
  • Botany, Ecology, and Taxonomy Studies
  • Cholinesterase and Neurodegenerative Diseases
  • Climate change impacts on agriculture
  • Cyclopropane Reaction Mechanisms
  • Quinazolinone synthesis and applications
  • Viral Infections and Outbreaks Research
  • Botanical Studies and Applications
  • Pharmacological Effects of Medicinal Plants
  • Long-Term Effects of COVID-19
  • Tannin, Tannase and Anticancer Activities
  • Rangeland Management and Livestock Ecology
  • Chromium effects and bioremediation
  • Nuts composition and effects
  • N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
  • COVID-19 epidemiological studies

University of Karachi
2015-2024

Civil Hospital Karachi
2022

Government College University, Faisalabad
2013-2016

University of Faisalabad
2015

University of California, Riverside
2007-2009

Cambridge Crystallographic Data Centre
2007

Addition of a sterically demanding cyclic (alkyl)(amino)carbene (CAAC) to AuCl(SMe 2 ) followed by treatment with [Et 3 Si(Tol)] + [B(C 6 F 5 4 ] − in toluene affords the isolable [(CAAC)Au(η -toluene)] complex. This cationic Au(I) complex efficiently mediates catalytic coupling enamines and terminal alkynes yield allenes not propargyl amines as observed other catalysts. Mono-, di-, tri-substituted can be used, well aryl-, alkyl-, trimethylsilyl-substituted alkynes. The reaction tolerates...

10.1073/pnas.0705809104 article EN Proceedings of the National Academy of Sciences 2007-08-14

Abstract Two very distinct chemical reactions, yet a single catalyst : A gold complex promotes the formation of tertiary enamines from variety terminal and internal alkynes. Subsequent addition alkyne to reaction mixture affords allenes (see scheme). magnified image

10.1002/chem.200802626 article EN Chemistry - A European Journal 2009-02-13

Traditional ecological knowledge, linguistic, and sociocultural perspectives are key contributors to environmental sustainability. Therefore, it is essential identify preserve this biocultural heritage, especially that of indigenous communities minorities. We conducted an ethnobotanical survey document the plant species used by Balti Shina living in buffer zone Deosai National Park (DNP), western Himalayas, Pakistan. A combination random purposive sampling techniques was adapted, targeting...

10.3390/biology10050434 article EN cc-by Biology 2021-05-14

The present study reports a convenient approach for the synthesis of thiophene sulfonamide derivatives (3a–3k) via Suzuki cross coupling reaction. This method involved reactions various aryl boronic acids and esters with 5-bromthiophene-2-sulfonamide (2) under mild suitable temperature conditions. compounds synthesized in were subjected to urease inhibition hemolytic activities. substitution pattern electronic effects different functional groups (i.e., Cl, CH3, OCH3, F etc.) available on...

10.1016/j.jscs.2014.04.007 article EN cc-by-nc-nd Journal of Saudi Chemical Society 2014-05-16

In general, benzothiazole derivatives have attracted great interest due to thier pharmaceutical and biological importance. New 2-amino-6-arylbenzothiazoles were synthesized in moderate excellent yields via Suzuki cross coupling reactions using various aryl boronic acids acid pinacol esters the antiurease nitric oxide (NO) scavenging activity of products also examined. The most active compound concerning urease enzyme inhibition was 6-phenylbenzo[d]thiazole-2-amine 3e, with an IC50 value...

10.3390/molecules18088845 article EN cc-by Molecules 2013-07-25

The present study describes the regioselective synthesis of novel 2,3,4,4<italic>a</italic>-tetrahydro-1<italic>H</italic>-carbazoles (<italic>syn</italic>-<bold>2(a–q)</bold>and<italic>anti</italic>-<bold>3(a–b)</bold>) from<sc>l</sc>-menthone<italic>via</italic>Fischer indole synthesis.

10.1039/c5ra10461k article EN RSC Advances 2015-01-01

Background: Traditional medicines knowledge is more famous and well-documented in rural remote areas Pakistan worldwide than urban areas. A present effort was made to document the ethnobotanical practices among communities of Karachi city provide basis for development natural drug discovery. Methods: For data collection, 177 local informants traditional healers were interviewed. Various quantitative indices such as relative frequency citation (RFC), fidelity level (FL), use value (UV),...

10.32859/era.28.40.1-26 article EN Ethnobotany Research and Applications 2024-03-14

A new COVID-19 variant, Omicron, has emerged from South Africa, indicating that the pandemic will not be over anytime soon. An unimaginable amount of economic damage resulted pandemic. Omicron and its implications are discussed in detail this review article. It also includes statistics on occurrence, mortality, recuperation Pakistan data country’s immunization coverage. Developing countries with unstable economies, such as Pakistan, have experienced increased difficulties. As a result, all...

10.3390/covid2100105 article EN cc-by COVID 2022-10-14

Abstract The current paper elaborates the wild edible plants’ (WEPs) diversity, and associated traditional knowledge among three ethnic groups of Balochistan Province, Pakistan. field trips were carried out in 2018-2020 employing purposive sampling techniques for respondents. We used open ended semi-structured interviews data collection. A total 195 reported 140 plant species 44 families 105 genera. Family Brassicaceae (10.17%) showed maximum representation along with Asteraceae (10%),...

10.21203/rs.3.rs-2480438/v1 preprint EN cc-by Research Square (Research Square) 2023-03-10

Abstract Traditional medicine uses and knowledge is more famous well documented in rural/remote areas Pakistan worldwide than the urban areas. The present effort was made to document ethnomedicinal practices among communities of Karachi city provides basis for development natural drug discovery. We are aware no other quantitative ethnobotanical investigation on use medicinal plants study area prior this study. For data collection, 177 local informants traditional healers were interviewed,...

10.21203/rs.3.rs-2984026/v1 preprint EN cc-by Research Square (Research Square) 2023-05-30

Traditional medicine uses and knowledge is more famous well documented in rural/remote areas Pakistan worldwide than the urban areas. The present effort was made to document ethnomedicinal practices among communities of Karachi city provides basis for development natural drug discovery. We are aware no other quantitative ethnobotanical investigation on use medicinal plants study area prior this study. For data collection, 177 local informants traditional healers were interviewed, using...

10.22541/au.170663845.56511452/v1 preprint EN Authorea (Authorea) 2024-01-30

Abstract The carbazoles are synthesized from L‐menthone and substituted phenyl hydrazines in acetic acid show promising inhibitory activities against acetyl‐ butyrylcholinesterase.

10.1002/chin.201549113 article EN ChemInform 2015-11-19

This research work entails the synthesis of transition metal complexes with methyl and methoxy aminoaryl derivatives. All ligands were synthesized from readily available benzisothiazole. Various solvent systems, under different sets reaction conditions tried to develop a method for complex formation. Methanol was proved be best complexation. The newly methodology then applied which identified by spectroscopic techniques. structural assignments, carried out studies. Conclusively, higher...

10.7439/ijpc.v3i2.41 article EN International Journal of Pharmaceutical Chemistry 2013-07-01

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at glance that was extracted from about 200 leading journals. To access of an article which published elsewhere, please select “Full Text” option. The original trackable via the “References”

10.1002/chin.200929041 article EN ChemInform 2009-06-29

Despite massive efforts to protect plant diversity around the world over last few decades, it is becoming increasingly evident that present policies are insufficient prevent continued trends of decline in biodiversity.The encroachment humans and their animals on protected areas causing changes its natural environment.This study was performed highlands Sra Ghurgai, Quetta District, Balochistan from July November 2020.The used a survey approach included purposive location selection,...

10.15244/pjoes/150016 article EN Polish Journal of Environmental Studies 2022-08-09
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