- Advanced Radiotherapy Techniques
- Prostate Cancer Treatment and Research
- Advanced X-ray and CT Imaging
- Medical Imaging Techniques and Applications
- Lung Cancer Diagnosis and Treatment
- Radiation Dose and Imaging
- Radiopharmaceutical Chemistry and Applications
- Radiomics and Machine Learning in Medical Imaging
- Radiation Therapy and Dosimetry
- Medical Image Segmentation Techniques
- PARP inhibition in cancer therapy
- Head and Neck Cancer Studies
- Prostate Cancer Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Esophageal Cancer Research and Treatment
- Advanced Neural Network Applications
- Medical Imaging and Analysis
- Brain Tumor Detection and Classification
Sun Yat-sen University
2015-2025
Sun Yat-sen University Cancer Center
2015-2025
Deformable multi-modal medical image registration aligns the anatomical structures of different modalities to same coordinate system through a spatial transformation. Due difficulties collecting ground-truth labels, existing methods often adopt unsupervised setting. However, it is hard design satisfactory metrics measure similarity images, which heavily limits performance. Moreover, due contrast difference organ in difficult extract and fuse representations modal images. To address above...
Abstract Background To investigate the effect of bladder volume (BV) and shape on consistency treatment interruption in prostate cancer radiotherapy (RT). Methods A total 275 patients who underwent radical RT our institution from April 2015 to December 2022 were enrolled. Bladder height, width, length defined recorded. The receiver operating characteristic (ROC) curves used evaluate best cut‐off point for shape. Logistic regression analysis was analyze relationship between setup errors...
To investigate the difference of fluence map optimization (FMO) and Stochastic platform (SPO) algorithm in a newly-introduced treatment planning system (TPS).34 cervical cancer patients with definitive radiation were retrospectively analyzed. Each patient has four plans: FMO fixed jaw plans (FMO-FJ) no (FMO-NFJ); SPO (SPO-FJ) (SPO-NFJ). Dosimetric parameters, Modulation Complexity Score (MCS), Gamma Pass Rate (GPR) delivery time analyzed among plans.For target coverage, SPO-FJ are best ones...
Metal artifacts due to spinal implants may affect the accuracy of dose calculation for radiotherapy. However, dosimetric impact metal artifact reduction (MAR) in stereotactic body radiotherapy (SBRT) plans has not been well studied. The objective this study was evaluate MAR SBRT planning with three clinically common algorithms.Gammex phantom and 10 patients' computed tomography (CT) images were studied investigate effects titanium implants. A commercial orthopedic algorithm employed reduce...
The purpose of this study was to accurately predict or classify the beam GPR with an ensemble model by using machine learning for SBRT(VMAT) plans.
Abstract Background: To investigate the potential benefit of cytoreductive radiotherapy (cRT) in metastatic castration-resistant prostate cancer (mCRPC) patients receiving abiraterone. Methods: From February 2014 to 2019, 149 mCRPC treated with abiraterone were identified. Patients cRT before failure (AbiRT group) matched by one-to-two propensity score without (non-AbiRT group). Results: The median follow-up was 23.5 months. Thirty (20.1%) AbiRT group, whereas 119 (79.9%) non-AbiRT group....
Abstract The authors have withdrawn this preprint due to author disagreement.
Abstract Background: To investigate the potential benefit of cytoreductive radiotherapy (cRT) in metastatic castration-resistant prostate cancer (mCRPC) patients receiving abiraterone. Methods: From February 2014 to 2019, 149 mCRPC treated with abiraterone were identified. Patients cRT before failure (AbiRT group) matched by one-to-two propensity score without (non-AbiRT group). Results: The median follow-up was 23.5 months. Thirty (20.1%) AbiRT group, whereas 119 (79.9%) non-AbiRT group....
Abstract Purpose: To identify planning systems and techniques suitable for different sites tumors by analyzing dosimetric differences using three commercial radiotherapy systems: Tomotherapy, Monaco Eclipse. Methods: We retrospectively analyzed 20 lung cancer 8 nasopharyngeal carcinoma (NPC), each patient plans were designed the systems. The dose distribution of target organs at risk (OARs) compared, monitor unit (MU) treatment time also evaluated. Results: For cancer, mean PGTV, PTV1 PTV2...
Abstract Background: To investigate the potential benefit of cytoreductive radiotherapy (cRT) in metastatic castration-resistant prostate cancer (mCRPC) patients receiving abiraterone. Methods: From February 2014 to 2019, 149 mCRPC treated with abiraterone were identified. Patients cRT before failure (AbiRT group) matched by one-to-two propensity score without (non-AbiRT group). Results: The median follow-up was 23.5 months. Thirty (20.1%) AbiRT group, whereas 119 (79.9%) non-AbiRT group....
Abstract Background Metal artifacts due to spinal implants can affect the accuracy of dose calculation for radiotherapy. However, dosimetric impact metal artifact reduction in Stereotactic Body Radiotherapy (SBRT) plans has not been well studied. The purpose this study was evaluate a commercial method different algorithms SBRT planning. Methods A gammex phantom and 10 clinical computed tomography (CT) images were selected investigate effects titanium implants. To achieve artefact...