A5003445882- Renal cell carcinoma treatment
- Radiomics and Machine Learning in Medical Imaging
- Hepatocellular Carcinoma Treatment and Prognosis
- Lung Cancer Diagnosis and Treatment
- Renal and related cancers
- Cancer, Hypoxia, and Metabolism
- Ultrasound and Hyperthermia Applications
- Medical Imaging and Pathology Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Artificial Intelligence in Healthcare and Education
- Radiology practices and education
- Multiple and Secondary Primary Cancers
- Advanced X-ray and CT Imaging
- Immune cells in cancer
- Liver Disease Diagnosis and Treatment
- Radiation Dose and Imaging
- Eicosanoids and Hypertension Pharmacology
- Advanced MRI Techniques and Applications
- ATP Synthase and ATPases Research
- AI in cancer detection
- Tracheal and airway disorders
- MRI in cancer diagnosis
- Peptidase Inhibition and Analysis
- Liver physiology and pathology
- Lung Cancer Research Studies
Brown University
2016-2025
Rhode Island Hospital
2017-2024
Lifespan
2022-2024
John Brown University
2024
Yale University
2023
Hospital of the University of Pennsylvania
2023
Johns Hopkins University
2023
Providence College
2017-2023
Society of Interventional Radiology
2023
American College
2023
To examine whether incorrect AI results impact radiologist performance, and if so, human factors can be optimized to reduce error. Multi-reader design, 6 radiologists interpreted 90 identical chest radiographs (follow-up CT needed: yes/no) on four occasions (09/20-01/22). No result was provided for session 1. Sham were sessions 2-4, 12 cases manipulated (8 false positives (FP), 4 negatives (FN)) (0.87 ROC-AUC). In the Delete (No Box) condition, told would not saved evaluation. Keep (Box),...
Purpose To evaluate the performance of radius, exophytic or endophytic, nearness to collecting system sinus, anterior posterior, and location relative polar lines (RENAL) nephrometry preoperative aspects dimensions used for anatomic classification (PADUA) scoring systems other tumor biometrics prediction local recurrence in patients with renal cell carcinoma after thermal ablation. Materials Methods This HIPAA-compliant study was performed a waiver informed consent institutional review board...
Background Preclinical testing of new locoregional therapies for pancreatic cancer has been challenging, due to the lack a suitable large animal model. Purpose To develop and characterize porcine model cancer. Unlike small animals, pigs have similar physiology, drug dosing, immune response humans. Locoregional therapy in can be performed using same size catheters devices as Methods The Oncopig is transgenic pig with Cre-inducible TP53R167H KRASG12D mutations. In 12 Oncopigs, CT-guided core...
To evaluate the performance of a software algorithm developed to streamline microwave liver ablation parameter selection and compare this that experienced interventional radiologists. Patients who underwent for treatment tumors were retrospectively identified. An automated platform was select top three 'best fit' combinations power, time, vendor given tumor achieve 5 mm minimal ablative margin (MAM). Generalized linear modeling used radiologists with respect selected parameters estimates...
BACKGROUND. Treatment options for patients with interstitial lung disease (ILD) who develop stage I-II non-small cell cancer (NSCLC) are severely limited, given that surgical resection, radiation, and systemic therapy associated significant morbidity mortality. OBJECTIVE. The aim of this study was to evaluate the safety efficacy percutaneous ablation NSCLC in ILD. METHODS. This retrospective included ILD treated three health systems between October 2004 February 2023. At each site, a single...
The primary challenge in thermal ablation of liver tumors (e.g. hepatocellular carcinoma and hepatic colorectal cancer) is the relatively high recurrence rate (~30%) for which incomplete at periphery tumor most common reason. In an attempt to overcome this, we have developed a novel accelerant (TA) agent capable augmenting microwave energy from distance normally unattainable by single antenna. This cesium-based block co-polymer compound transforms liquid gel body temperature intrinsically...
Transbronchial microwave ablation (MWA) is a promising novel therapy. Despite advances in bronchoscopy and virtual navigation, real time image guidance of probe delivery lacking, distal maneuverability limited. Cone-beam computed tomography (CBCT) based augmented fluoroscopy using steerable sheaths may help overcome these shortcomings. The aim this study was to evaluate feasibility accuracy guided transbronchial MWA with sheath without bronchoscope. In prospective study, procedures were...