A5028307213- Gastric Cancer Management and Outcomes
- Gastrointestinal Tumor Research and Treatment
- Metastasis and carcinoma case studies
- Cancer Cells and Metastasis
- Cancer Genomics and Diagnostics
- Cancer Research and Treatments
- Cell Adhesion Molecules Research
- Minimally Invasive Surgical Techniques
- Esophageal and GI Pathology
- Glycosylation and Glycoproteins Research
- Colorectal Cancer Surgical Treatments
- Bariatric Surgery and Outcomes
- Cancer Immunotherapy and Biomarkers
- Hepatocellular Carcinoma Treatment and Prognosis
- Pancreatic and Hepatic Oncology Research
- Colorectal Cancer Treatments and Studies
- Esophageal Cancer Research and Treatment
- Nutrition and Health in Aging
- Diet and metabolism studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Multiple and Secondary Primary Cancers
- Surgical Simulation and Training
- Helicobacter pylori-related gastroenterology studies
- Body Contouring and Surgery
- Genetic factors in colorectal cancer
Dankook University
2025
Dankook University Hospital
2024-2025
Ajou University
2016-2025
Loma Linda University
2025
Ajou University Hospital
2015-2024
Western University
2024
Catholic University of Korea
2020
Seoul St. Mary's Hospital
2020
Seoul National University Bundang Hospital
2012-2018
Seoul National University
2011-2014
Although the tumor stroma in solid tumors like gastric cancer (GC) plays a crucial role chemo-resistance, specific targets to inhibit interaction between stromal and cells have not yet been utilized clinical practice. The present study aims determine whether cancer-associated fibroblasts (CAFs), major component of stroma, confer chemotherapeutic resistance GC cells, discover potential improve chemo-response GC. To identify CAF-specific proteins signal transduction pathways affecting...
Although several studies report risk factors for anastomotic leakage after gastrectomy gastric cancer, they have yielded conflicting results. The present retrospective cohort study was performed to identify that are consistently associated with stomach cancer.All consecutive patients who underwent at a single surgical unit between May 2003 and December 2012 were identified retrospectively. associations 23 variables related patient history, diagnosis, surgery assessed analyzed logistic...
To compare long-term outcomes between robotic and LG approaches using propensity score weighting based on a generalized boosted method to control for selection bias.Minimally invasive surgical GC are increasing, yet limited evidence exists of gastrectomy (RG).Patients (n = 2084) with stages I-III who underwent or RG 2009 2017 were analyzed. Generalized was used estimate derived from all available preoperative characteristics. Long-term compared the adjusted Kaplan-Meier weighted Cox...
Identification of the infrapyloric artery (IPA) type is a key component pylorus-preserving gastrectomy. As indocyanine green (ICG) fluorescence technique known to help visualize blood vessels and flow during reconstruction, we speculated that this emerging would be helpful in identifying IPA type. From August 2015 February 2016, 20 patients who underwent robotic or laparoscopic gastrectomy were prospectively enrolled. After intravenous injection approximately 3 mL ICG (2.5 mg/mL),...
Abstract Textbook outcome is a composite quality measurement of short-term outcomes for evaluating complex surgical procedures. We compared textbook and survival robotic total gastrectomy (RTG) with those laparoscopic (LTG). retrospectively reviewed 395 patients (RTG, n = 74; LTG, 321) who underwent curative gastric cancer via minimally invasive approaches from 2009 to 2018. performed propensity score matched analysis adjust potential selection bias. included negative resection margin, no...
Abstract Background Tumor cells of diffuse-type gastric cancer (DGC) are discohesive and infiltrate into the stroma as single or small subgroups, so significantly impacts DGC progression. Cancer-associated fibroblasts (CAFs) major components tumor stroma. Here, we identified CAF-specific secreted molecules investigated mechanism underlying CAF-induced Methods We conducted transcriptome analysis for paired normal fibroblast (NF)-CAF isolated from patient tissues proteomics conditioned media...
Abstract Genomic alterations in tumors play a pivotal role determining their clinical trajectory and responsiveness to treatment. Targeted panel sequencing (TPS) has served as key tool over the past decade, but advancements costs bioinformatics have now made whole-genome (WGS) feasible single-assay approach for almost all cancer genomes settings. This paper reports on findings of prospective, single-center study exploring real-world utility WGS (tumor matched normal tissues) two primary...
Discoidin domain receptor 1 (DDR1) is activated by fibrillar (triple-helical) collagens and collagen IV, which are major components of tumor stroma; thus, DDR1 might be a critical mediator communication between cancer cells stroma. The aim this study was to investigate the effect inhibition on stroma-induced peritoneal metastasis in gastric carcinoma. We analyzed immunohistochemistry correlation expression pattern recurrence carcinoma tissues from previously characterized established patient...
Background . Although Billroth II (BII) reconstruction is simpler and faster than I or Roux-en-Y (RY) in patients undergoing totally laparoscopic distal gastrectomy (TLDG), BII associated with several complications, including more severe bile reflux. Braun anastomosis may be a better alternative to RY reconstruction. Methods This retrospective study included 56 consecutive who underwent TLDG for gastric cancer, followed by reconstruction, between January 2013 December 2015. Surgical...