A5027466874- Folate and B Vitamins Research
- Obstructive Sleep Apnea Research
- Renal and related cancers
- Genetic factors in colorectal cancer
- Cancer Genomics and Diagnostics
- Infectious Encephalopathies and Encephalitis
- Neurological diseases and metabolism
- Neuroscience of respiration and sleep
- Genomics and Phylogenetic Studies
- Rabbits: Nutrition, Reproduction, Health
- Hereditary Neurological Disorders
- GDF15 and Related Biomarkers
- Animal Genetics and Reproduction
- Calcium Carbonate Crystallization and Inhibition
- Respiratory viral infections research
- Cellular Mechanics and Interactions
- Bone health and osteoporosis research
- Lung Cancer Treatments and Mutations
- Water Quality and Pollution Assessment
- Pancreatic function and diabetes
- Aquatic Ecosystems and Phytoplankton Dynamics
- Heavy Metal Exposure and Toxicity
- Tissue Engineering and Regenerative Medicine
- DNA Repair Mechanisms
- Parathyroid Disorders and Treatments
University of Tennessee Health Science Center
2023-2024
Macrogen (South Korea)
2020
Theravance Biopharma (United States)
2019
Seoul National University Hospital
2016
Ewha Womans University
2008
De novo assembly and phasing of the genome an individual from Korea using a combination different sequencing approaches provides useful population-specific reference represents most contiguous human so far. Jeong-Sun Seo colleagues report de PacBio long-read sequencing, Illumina short-read 10X Genomics linked reads, bacterial artificial chromosome (BAC) BioNano optical mapping. This to date. The authors use this close gaps in map structural variation. Advances provide opportunity investigate...
Novel coronavirus (SARS-CoV-2) is found to cause a large outbreak started from Wuhan since December 2019 in China and SARS-CoV-2 infections have been reported with epidemiological linkage 25 countries until now.We isolated the oropharyngeal sample obtained patient first laboratory-confirmed infection Korea.Cytopathic effects of Vero cell cultures were confluent 3 days after blind passage sample.Coronavirus was confirmed spherical particle having fringe reminiscent crown on transmission...
Abstract Genomic alterations in tumors play a pivotal role determining their clinical trajectory and responsiveness to treatment. Targeted panel sequencing (TPS) has served as key tool over the past decade, but advancements costs bioinformatics have now made whole-genome (WGS) feasible single-assay approach for almost all cancer genomes settings. This paper reports on findings of prospective, single-center study exploring real-world utility WGS (tumor matched normal tissues) two primary...
Abstract Genomic alterations in tumors play a pivotal role determining their clinical trajectory and responsiveness to treatment. While targeted panel sequencing ( TPS ) has been key tool over the past decade, advancements costs bioinformatics have now made whole-genome WGS feasible single-assay approach for almost all cancer genomes settings. This paper reports on findings of prospective, single-center study exploring real-world utility (tumor matched normal tissues) with two primary...
Tubular epithelial cell fate following exposure to various types of injurious stimuli can be decided at distinct cycle checkpoints. One such checkpoint occurs during mitosis, known as the spindle assembly checkpoint, and is tightly regulated through actions division protein 20 (CDC20). Due our paucity knowledge about role CDC20 in kidney, present study was designed investigate expression levels distribution within kidney how pharmacological inhibition function affects recovery using rodent...
Tubular epithelial cell damage can be repaired through a series of complex signaling pathways. An early event in many forms tubular is the observation DNA damage, which by specific pathways depending upon type genomic alteration.. In this study, we report that catalytic subunit protein kinase (DNA-PKcs), central repair enzyme involved sensing and performing double stranded break repair, plays an important role extent following exposure to injurious acute chronic stimuli. Selective loss...