A5089068543- Gastric Cancer Management and Outcomes
- Lung Cancer Treatments and Mutations
- Metastasis and carcinoma case studies
- Colorectal Cancer Treatments and Studies
- Lung Cancer Research Studies
- Head and Neck Cancer Studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Breast Implant and Reconstruction
- Gastrointestinal Tumor Research and Treatment
- Breast Cancer Treatment Studies
- Peptidase Inhibition and Analysis
- Cancer Treatment and Pharmacology
- Cancer Genomics and Diagnostics
- Advancements in Photolithography Techniques
- Lung Cancer Diagnosis and Treatment
- Electron and X-Ray Spectroscopy Techniques
- Pancreatic and Hepatic Oncology Research
- Brain Metastases and Treatment
- Hematopoietic Stem Cell Transplantation
- Reconstructive Surgery and Microvascular Techniques
- Inflammatory Biomarkers in Disease Prognosis
- Acute Myeloid Leukemia Research
- Neutropenia and Cancer Infections
- Lymphoma Diagnosis and Treatment
- Cancer-related Molecular Pathways
Hanyang University
2007-2025
Kosin University Gospel Hospital
2020-2025
Ajou University
2015-2024
Kosin University
2020-2024
Sidney Kimmel Comprehensive Cancer Center
2024
Johns Hopkins University
2024
Thomas Jefferson University
2024
University of Maryland, Baltimore
2024
Weatherford College
2023
UCLA Medical Center
2023
PURPOSE Adjuvant chemotherapy after D2 gastrectomy is standard for resectable locally advanced gastric cancer (LAGC) in Asia. Based on positive findings perioperative European phase III studies, the PRODIGY study (ClinicalTrials.gov identifier: NCT01515748 ) investigated whether neoadjuvant docetaxel, oxaliplatin, and S-1 (DOS) followed by surgery adjuvant could improve outcomes versus treatment Korean patients with LAGC. PATIENTS AND METHODS Patients 20-75 years of age, Eastern Cooperative...
Purpose This trial was conducted to determine the optimal duration of chemotherapy in Korean patients with advanced non–small-cell lung cancer (NSCLC). Patients and Methods stages IIIB IV NSCLC who had not progressed after two cycles were randomly assigned receive either four (arm A) or B) more third-generation, platinum-doublet treatment. Results Of 452 enrolled patients, 314 groups. One-year survival rates 59.0% arm A 62.4% B, difference 3.4% (95% CI, −8.0 4.8) met predefined criteria for...
Background/Objectives: Oncoplastic breast-conserving surgery (OBCS) with acellular dermal matrix (ADM) has gained prominence in contemporary breast cancer management, yet evidence-based guidelines for selecting optimal ADM techniques based on the tumor location remain undefined. This investigation evaluated impact of quadrant and application methodology aesthetic outcomes, patient satisfaction, postoperative complications following OBCS. Methods: retrospective comparative analysis examined...
In ADAURA, adjuvant osimertinib significantly improved disease-free survival versus placebo in resected stage IB to IIIA EGFR-mutated NSCLC. We report in-depth analyses of three-year safety, tolerability, and health-related quality life (HRQoL) from ADAURA.Patients were randomized 1:1 80 mg or once daily for up 3 years. Safety assessments performed at baseline, week 2, 4, 12, every 12 weeks until treatment completion discontinuation, 28 days after was stopped. The SF-36 survey measured HRQoL...
Objectives: Exon 19 deletion and L858R mutation in exon 21 of the epidermal growth factor receptor (EGFR) are both common mutations that predict a good response to EGFR tyrosine kinase inhibitors non–small cell lung cancer (NSCLC). However, existence clinically significant difference sensitivity among different subtypes is still matter debate. Materials Methods: The outcome 60 mutation-positive advanced NSCLC patients who received first-line gefitinib therapy (250 mg/d) was retrospectively...
Abstract We examined the predictive value of neutrophil–lymphocyte ratio (NLR) by examining their association with baseline presence and subsequent development brain metastases in patients stage IV non-small cell lung cancer (NSCLC). NLR for metastasis 260 NSCLC. Logistic regression models competing risk analysis were used to determine metastases. Multivariate reveals that high (≥4.95) had significantly more at diagnosis than those low (Odds Ratio = 2.59, P 0.01). In who no metastasis, risks...
Abstract This study addresses the limited non-invasive tools for Oral Cavity Squamous Cell Carcinoma (OSCC) survival prediction by identifying Computed Tomography (CT)-based biomarkers to improve prognosis prediction. A retrospective analysis was conducted on data from 149 OSCC patients, including CT radiomics and clinical information. An ensemble approach involving correlation analysis, score screening, Sparse-L1 algorithm used select functional features, which were then build Cox...
Introduction This study aimed to identify CT-based imaging biomarkers for locoregional recurrence (LR) in Oral Cavity Squamous Cell Carcinoma (OSCC) patients. Methods Computed tomography scans were collected from 78 patients with OSCC who underwent surgical treatment at a single medical center. We extracted 1,092 radiomic features gross tumor volume each patient’s pre-treatment CT. Clinical characteristics also obtained, including race, sex, age, tobacco and alcohol use, staging, modality. A...
This study investigates the differences in lithographic impact of particles on pellicle surface depending type extreme ultraviolet (EUV) mask pattern. Using an EUV ptychography microscope, we analyzed how imaging performance is affected by locally obstructed diffraction caused a 10 μm × patterned tin particle intentionally fabricated surface. The resulting critical dimension variations were found to be approximately three times greater line-and-space patterns than contact hole patterns....
Background/Objectives: To quantitatively assess the long-term volume stability of acellular dermal matrix (ADM) in oncoplastic breast-conserving surgery (OBCS) and analyze surgical aesthetic outcomes. Methods: This retrospective study examined 172 breast cancer patients who underwent OBCS with immediate ADM-based replacement (2020-2022). Patients received either diced ADM sheet (n = 102) or paste 70). The was evaluated using MRI at 6, 12, 24 months postoperatively. Results: Long-term...
Abstract This study aimed to identify CT-based imaging biomarkers for locoregional recurrence (LR) in Oral Cavity Squamous Cell Carcinoma (OSCC) patients. Our involved a retrospective review of 78 patients with OSCC who underwent surgical treatment at single medical center. An approach involving feature selection and statistical model diagnostics was utilized biomarkers. Two radiomics biomarkers, Large Dependence Emphasis (LDE) the Gray Level Matrix (GLDM) Long Run (LRE) Length (GLRLM) 3D...
Abstract Purpose: The present study evaluated the prognostic significance of apoptosis-related proteins, p53, Bcl-2, Bax, and galectin-3 in patients with locally advanced esophageal cancer treated definitive chemoradiotherapy. Experimental Design: A total 63 (squamous cell carcinoma: 62; adenocarcinoma: 1; stages II-IV) were chemoradiotherapy using 5-fluorouracil cisplatin combined radiotherapy. Pretreatment tumor biopsy specimens analyzed for expression by immunohistochemistry. Results:...
Human papillomavirus (HPV) is a well-established oncogenic virus of cervical, anogenital, and oropharyngeal cancer. Various subtypes HPV have been detected in 0% to 60% breast cancers. The roles the carcinogenesis cancer remain controversial. This study was performed determine prevalence HPV-positive Korean patients evaluate possibility carcinogenic effect on breast.Meta-analysis 22 case-control studies for infection A total 123 cancers, nine intraductal papillomas 13 nipple tissues with...
The S100 gene family, which comprises over 20 members, including S100A1, S100A2, S100A8, S100A9, profilaggrin, and hornerin encodes low molecular weight calcium-binding proteins with physiological pathological roles in keratinization. Recent studies have suggested a link between human cancer progression. purpose of the present study was to determine expression levels hornerin, S100A9 evaluate their progression invasive ductal carcinoma (IDC). Seventy cases situ (DCIS), IDC, metastatic lymph...
ObjectiveThe present study evaluated the prognostic significance of apoptosis-related proteins p53, Bax and galectin-3 in patients with non-small cell lung cancer (NSCLC) treated surgical resection.