A5026555298- Gastric Cancer Management and Outcomes
- Gastrointestinal Tumor Research and Treatment
- Metastasis and carcinoma case studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Colorectal Cancer Treatments and Studies
- Esophageal and GI Pathology
- Sarcoma Diagnosis and Treatment
- Esophageal Cancer Research and Treatment
- Lung Cancer Treatments and Mutations
- Pancreatic and Hepatic Oncology Research
- Cancer Genomics and Diagnostics
- Helicobacter pylori-related gastroenterology studies
- Genetic factors in colorectal cancer
- Neuroendocrine Tumor Research Advances
- Lung Cancer Diagnosis and Treatment
- Colorectal and Anal Carcinomas
- Enhanced Recovery After Surgery
- Gastrointestinal disorders and treatments
- Nutrition and Health in Aging
- Lung Cancer Research Studies
- Cancer Immunotherapy and Biomarkers
- Cancer Cells and Metastasis
- Multiple and Secondary Primary Cancers
- Colorectal Cancer Surgical Treatments
- Dysphagia Assessment and Management
Shizuoka Cancer Center
2016-2025
Azienda Ospedaliera Universitaria Senese
2024
University of Siena
2024
The Japanese Society of Gastroenterological Surgery
2024
Royal Marsden Hospital
2024
Japan Clinical Cancer Research Organization
1993-2019
Shizuoka General Hospital
2018
Niigata University
1967-2017
Keio University
2017
Yokohama Municipal Citizen's Hospital
2017
Complicated gastric lymphatic drainage potentially undermines the utility of sentinel node (SN) biopsy in patients with cancer. Encouraged by several favorable single-institution reports, we conducted a multicenter, single-arm, phase II study SN mapping that used standardized dual tracer endoscopic injection technique.Patients previously untreated cT1 or cT2 adenocarcinomas < 4 cm gross diameter were eligible for inclusion this study. was performed using technique. Following identified SNs,...
EGF receptor (EGFR) and HER2 positivity are considered to be negative prognostic factors in gastric cancer. Biomarker analysis was conducted evaluate the impact of EGFR expression on outcome patients enrolled Adjuvant Chemotherapy Trial TS-1 for Gastric Cancer (ACTS-GC), a randomized controlled trial comparing postoperative adjuvant S-1 therapy with surgery alone 1,059 stage II/III cancer.Formalin-fixed, paraffin-embedded surgical specimens were retrospectively examined 829 (78.3%). The...
Objective: The aim of the study was to determine optimal extent lymph node dissection for 2 histological types esophagogastric junction (EGJ) tumors based on incidence metastasis in a prospective nationwide multicenter study. Background: Because most previous studies were retrospective, surgical procedure EGJ has not been standardized. Methods: Patients with cT2-T4 adenocarcinoma or squamous cell carcinoma located within 2.0 cm enrolled before surgery. Surgeons dissected all nodes...
Importance Evidence of implementation laparoscopic gastrectomy for locally advanced gastric cancer is currently insufficient, as the primary end point in previous prospective studies was evaluated at a median follow-up time 3 years. More robust evidence necessary to verify noninferiority gastrectomy. Objective To compare 5-year survival outcomes between laparoscopy-assisted distal (LADG) and open (ODG) with D2 lymph node dissection cancer. Design, Setting, Participants This multicenter,...
Abstract Purpose: To evaluate the efficacy and toxicity of docetaxel in combination with a novel oral 5-fluorouracil analogue S-1 for patients advanced or recurrent gastric cancer. Experimental Design: Patients adenocarcinoma stomach up to one previous chemotherapy regimen were treated i.v. 40 mg/m2 on day 1 80 mg/m2/d days 14 every 3 weeks. Results: Forty-eight (median age, 65 years; range, 25-75 years) received total 272 treatment cycles (median, 4; 1-17). No complete responses 27 partial...
A Phase III study was started in Japan to evaluate the non-inferiority of overall survival laparoscopy-assisted distal gastrectomy with open patients clinical IA (T1N0) or IB [T1N1 T2(MP)N0] gastric cancer. This followed previous II confirm safety (JCOG0703) and began March 2010. total 920 will be accrued from 33 institutions within 5 years. The primary endpoint is survival. secondary endpoints are relapse-free survival, proportion completion, conversion surgery, adverse events, short-term...
A large-scale multicenter historical cohort study was conducted to investigate the efficacy of laparoscopic gastrectomy (LG) in comparison open (OG) for locally advanced gastric cancer.LG is now practiced widely, but its applicability cancer still controversial. As oncologic outcomes randomized trials are pending, there an urgent need information that would be relevant current practice.Through a consensus meeting involving surgeons and biostatisticians, 30 preoperative variables possibly...