A5101893272- Gastric Cancer Management and Outcomes
- Metastasis and carcinoma case studies
- Gastrointestinal Tumor Research and Treatment
- Esophageal and GI Pathology
- Esophageal Cancer Research and Treatment
- Soft Robotics and Applications
- Evolutionary Algorithms and Applications
- Surgical Simulation and Training
- Building Energy and Comfort Optimization
- Genetic factors in colorectal cancer
- Bariatric Surgery and Outcomes
- Colorectal Cancer Surgical Treatments
- Gaze Tracking and Assistive Technology
- Anatomy and Medical Technology
- Head and Neck Cancer Studies
- Cancer-related gene regulation
- Helicobacter pylori-related gastroenterology studies
- Intracranial Aneurysms: Treatment and Complications
- Educational Robotics and Engineering
- Advanced MRI Techniques and Applications
- Pancreatic and Hepatic Oncology Research
- Epigenetics and DNA Methylation
- Vascular Malformations Diagnosis and Treatment
- Cancer Cells and Metastasis
- Simulation and Modeling Applications
Mie University
2025
Dokkyo Medical University
2019-2024
Shonan Institute of Technology
2018-2022
Tokyo Medical and Dental University
2010-2019
Osaka City University
2019
Nagoya Institute of Technology
2007-2019
Waseda University
2019
University of Brawijaya
2019
Interface (United States)
2019
Human Factors (Norway)
2019
Importance Evidence of implementation laparoscopic gastrectomy for locally advanced gastric cancer is currently insufficient, as the primary end point in previous prospective studies was evaluated at a median follow-up time 3 years. More robust evidence necessary to verify noninferiority gastrectomy. Objective To compare 5-year survival outcomes between laparoscopy-assisted distal (LADG) and open (ODG) with D2 lymph node dissection cancer. Design, Setting, Participants This multicenter,...
Intestinal ischemia, or inadequate blood flow to the intestine, is caused by a variety of disorders and conditions. The quickness with which problem brought medical attention for diagnosis treatment has great effects on outcome ischemic injury. Recently, hyperspectral sensors have advanced emerged as compact imaging tools that can be utilized in diagnostics. Hyperspectral provides powerful tool noninvasive tissue analyses. In this paper, camera, visible invisible wavelengths, been evaluated...
During the last few decades, many studies have been performed on early detection of cancer using noninvasive or minimally invasive techniques in lieu traditional excisional biopsy. Early can make an immense difference because treatment is often simpler and more effective when diagnosed at stage. Cancer detecting methods may help physicians to diagnose cancer, dissect malignant region with a safe margin, evaluate tumor bed after resection. In this paper, advanced hyperspectral imaging system...
The present study evaluated the efficacy of Roux-en-Y (R-Y) reconstruction and Billroth-I (B-I) after laparoscopy-assisted distal gastrectomy (LADG).Between October 2000 February 2006, a total 133 consecutive patients who underwent LADG for gastric carcinoma were classified into 2 groups according to (B-I, n = 65; R-Y, 68). Parameters analyzed included tumor characteristics, operative details, postoperative outcomes, nourishment state. Endoscopic findings remnant lower esophagus at 12 months...
Epigenetic silencing of genes by aberrant DNA methylation is recognized as a crucial component the mechanism underlying tumorigenesis. However, relationship between and past lifestyle in cancer patients remains largely unknown. We examined statuses 6 tumor-related genes, CDX2 (homeobox transcription factor), BMP-2 (bone morphogenetic protein 2), p16 (INK4A), CACNA2D3 (calcium channel-related), GATA-5 (transcription factor) ER (estrogen receptor), 106 primary gastric carcinomas...
MicroRNAs (miRNAs) are endogenous small noncoding RNAs that negatively regulate gene expression by interfering with the translation or stability of target transcripts. Some tumor-suppressive miRNAs can concurrently multiple cancer-promoting genes and may be useful as therapeutic anticancer agents. However, development drug delivery systems is critical for implementation miRNA-based therapeutics. We have previously demonstrated enforced miR-634 effectively induces apoptosis directly targeting...
To investigate the efficacy of magnetic resonance imaging (MRI) in assessment thyroid-associated ophthalmopathy (TAO), 51 patients with TAO were evaluated by ophthalmologic examinations and MRI at 0.5 T. Thickness extraocular muscles (EM) was measured T1-weighted image. Signal intensities EM orbital connective tissue (OCT) short inversion time recovery (STIR) image expressed as a ratio comparison to signal intensity cerebral substantia alba (SI, ratio). Significant enlargement one or more...
The mammalian target of rapamycin (mTOR), a Ser/Thr protein kinase that mediates intracellular signalling related to cell growth, proliferation, and differentiation, has received considerable interest as possible for cancer treatment. We evaluated the correlation mTOR expression with clinicopathological features, outcomes, Akt, an upstream regulator mTOR, in gastric cancer. Tumour samples were obtained from 109 patients adenocarcinomas who underwent radical gastrectomy. expressions...
Abstract We present an application of a new three‐dimensional head‐mounted display system that combines high‐definition organic electroluminescent with endoscope to minimally invasive surgery, using gasless single‐port radical nephrectomy procedures as model. This presents the surgeon higher quality magnified imagery in front eyes regardless head position, and simultaneously allows direct vision by moving angle sight downward. It is also significantly less expensive than current robotic...
The overexpression of fibroblast growth factor receptor (FGFR) 2 is an established prognostic and treatment target in gastric cancer. However, the roles other FGFRs have not been fully elucidated. In this study, we investigated correlations expression FGFR1-4 with clinicopathological characteristics outcomes Tumor samples were obtained from 222 patients adenocarcinoma who underwent gastrectomy between 2003 2007. each FGFR was measured tumors by immunohistochemical analysis. FGFR1, FGFR2 or...
Targeting protein for Xenopus kinesin-like 2 (TPX2) is a microtubule-associated required microtubule formation in human cells. Several studies have demonstrated that TPX2 overexpressed multiple tumor types and promotes growth metastasis. However, there been few reports regarding its role gastric cancer. In this study, we evaluated expression investigated correlations with cancer clinicopathological features prognosis. Tumor samples were obtained from 290 patients adenocarcinoma who had...
Abstract Aim This study aimed to evaluate the association between surgeons certified via Endoscopic Surgical Skill Qualification System (ESSQS) of Japan Society for Surgery (JSES) and surgical outcomes laparoscopic distal gastrectomy (LDG) low anterior resection (LLAR). Methods Japanese National Clinical Database data on patients undergoing LDG LLAR 2014‐2016 were analyzed retrospectively. The proportion cases performed by ESSQS‐certified was calculated each procedure, clinicopathological...
Gastric cancer is the second most common cause of deaths worldwide. The identification molecular genetic parameters that are associated with response to chemotherapy and prognosis utmost interest. We examined methylation apoptosis-related genes, TMS1 DAPK, in 81 primary gastric cancers using methylation-specific PCR compared their status clinicopathological findings. Aberrant DAPK genes was detected 26 (32.1%) tumors 18 (22.2%) tumors, respectively. overall survival patients both methylated...