A5052764781- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiac Structural Anomalies and Repair
- Vascular anomalies and interventions
- COVID-19 Clinical Research Studies
- Venous Thromboembolism Diagnosis and Management
- Cardiac Valve Diseases and Treatments
- Neurological disorders and treatments
- SARS-CoV-2 and COVID-19 Research
- Non-Invasive Vital Sign Monitoring
- Long-Term Effects of COVID-19
- ECG Monitoring and Analysis
- Cardiovascular Syncope and Autonomic Disorders
- Central Venous Catheters and Hemodialysis
- Coronary Artery Anomalies
- Nursing Roles and Practices
- Vascular Procedures and Complications
- Antiplatelet Therapy and Cardiovascular Diseases
- Diverse Scientific Research Studies
- Acute Myocardial Infarction Research
- Resilience and Mental Health
- Health Systems, Economic Evaluations, Quality of Life
- Hip and Femur Fractures
St George’s University Hospitals NHS Foundation Trust
2020-2025
St George's Hospital
2019-2024
East Lancashire Hospitals NHS Trust
2024
Hammersmith Hospital
2024
St George's Hospital
2020-2023
St George's, University of London
2012-2023
St Peter's Hospital
2021-2022
Ashford and St Peter's Hospitals NHS Foundation Trust
2012-2022
Royal Surrey County Hospital
2021
Pamela Youde Nethersole Eastern Hospital
2019
Thermal injury to the oesophagus is an important cause of life-threatening complication after ablation for atrial fibrillation (AF). protection oesophageal lumen by infusing cold liquid reduces thermal a limited extent. We tested ability more powerful method temperature control reduce incidence injury.A single-centre, prospective, double-blinded randomized trial was used investigate ensoETM device protect from injury. This compared in 1:1 randomization with group standard practice utilizing...
Abstract Introduction The IMPACT study established the role of controlled esophageal cooling in preventing thermal injury during radiofrequency (RF) ablation for atrial fibrillation (AF). effect on lesion delivery and procedural patient outcomes had not been previously studied. objective was to determine formation RF lesions, ability achieve endpoints, clinical outcomes. Methods Participants trial underwent AF guided by Ablation Index (30 W at 350–400 AI posteriorly, 40 ≥450 anteriorly). A...
Abstract Background Catheter ablation is a well-established treatment for atrial fibrillation (AF), effectively reducing AF burden, improving quality of life, and decreasing cardiovascular risk. The efficacy the safety between point-by-point radiofrequency (RF) one-shot techniques such as cryoablation or pulsed field are similar. Recently, novel ultra-low temperature (ULTC) has been introduced, achieving temperatures low -196°C versus -89°C with traditional cryoballoon ablation. This...
Abstract Aims Transvenous lead extraction (TLE) is important in the management of cardiac implantable electronic devices but carries risk. It most commonly completed from superior access, often with ‘bail-out’ support via femoral approach. Superior and inferior access may be used tandem, which has been proposed as an advance safety efficacy. The aim this study to evaluate efficacy Tandem Method ‘Tandem’ procedure entailed grasping targeted right atrium provide countertraction a rotational...
To chart the effect of COVID-19 pandemic on activity interventional electrophysiology services in affected regions.We reviewed laboratory records three cities: Wenzhou China, Milan Italy, and London UK. We inspected catheter lab interviewed electrophysiologists each centre to gather information impact working patterns health staff members patients. There was a striking decline centres. The occurred within week recognition widespread community transmission virus region shows correlation with...
Troponin is a crucial biomarker for the diagnosis of an acute coronary syndrome (ACS). It rises in response to myocardial injury from significant ischaemia caused by obstructive artery disease ['classical' infarction (MI)]. However, raised levels have also been noted conditions not recognized as classical ACS. This may include MI with non-obstructed arteries such takotsubo cardiomyopathy and other or chronic pulmonary embolus kidney disease. commonly labelled 'falsely elevated' troponin...
The Sars-Cov-2 infection is a multisystem illness that can affect the cardiovascular system. Tachyarrhythmias have been reported but prevalence of bradyarrhythmia unclear. Cases described transient high-degree atrioventricular (AV) block in COVID-19 were managed conservatively.A database all patients requiring temporary or permanent pacing two linked cardiac centers was used to compare number procedures required during first year pandemic compared corresponding period earlier....
Abstract Funding Acknowledgements Type of funding sources: Private company. Main source(s): Dr Leung has received research support from Attune Medical (Chicago, IL). Gallagher Background Randomized evidence shown that controlled oesophageal cooling is effective at reducing thermal injury during radiofrequency (RF) ablation for atrial fibrillation (AF) compared to standard care. The effect on lesion formation in left myocardium and patient outcomes 12-months had not been previously studied....
Abstract Background Proactive esophageal cooling is increasingly being utilized, and now FDA cleared, to reduce the likelihood of ablation-related injury resulting from radiofrequency (RF) cardiac ablation atrial fibrillation (AF). One-year follow-up largest randomized controlled study, IMPACT trial, showed a trend towards improvement in long-term efficacy versus luminal temperature (LET) monitoring. With larger data sets available for analysis, we sought determine 1-year freedom arrhythmia...
A patient with shocks from his ICD related to AF underwent redo ablation. The only identifiable target was the superior vena cava. This isolated using ultra-low cryotherapy, eliminating episodes of AF. 53-year-old man non-ischemic dilated cardiomyopathy (ejection fraction 35%), received recurrent dual-chamber implantable cardioverter-defibrillator (ICD) because atrial fibrillation (AF), 7 years after an extensive radiofrequency ablation including pulmonary veins (PVs) isolation, left roof,...
Abstract Background Transvenous lead extraction (TLE) is vital to the management of cardiac implantable electronic devices (CIEDs). Evolving tools and techniques have contributed an improvement in procedural safety efficacy. The jugular access advantageous TLE, providing a linear, direct path heart for sheaths. However, transfer with deployed locking stylet from subclavian carries risk cardiovascular injury. A novel pull-through technique has been described safe native site access,...
Background Differences in outcomes between bioresorbable vascular scaffold (BVS) systems and drug-eluting metal stents (DES) have not been fully evaluated. We aimed to compare clinical angiographic randomised studies of patients with coronary artery disease (CAD), a secondary analysis performed among registry studies. Methods A meta-analysis comparing BVS DES CAD. Overall estimates treatment effect were calculated random-effects model fixed-effects model. Results In 6 trials (3818 patients),...
COVID-19 causes severe illness that results in morbidity and mortality. Electrocardiographic features, including QT prolongation, have been associated with poor acute outcomes; data on the medium-term outcomes remain scarce. This study evaluated 1-year of patients who survived infection. Methods Materials: Data 159 during first wave (1 March 2020−18 May 2020) were collected. Patient demographics, laboratory findings electrocardiography evaluated. Patients subsequently died within index...
To investigate the abnormalities of coronary venous system in candidates for cardiac resynchronization therapy (CRT) and describe methods circumventing resulting difficulties.From four implanting institutes, data all CRT implants between October 2008 2020 were screened abnormal anatomy, defined as an anatomical variation not conforming to accepted 'normal' anatomy. Patient demographics, procedural detail, subsequent left ventricle (LV) lead pacing indices collected.From a total 3548...
First-line management of paroxysmal atrial fibrillation: is it time for a ‘pill in the bin’ approach? A discussion on STOP AF First, EARLY AF, Cryo-FIRST, and EAST-AF NET 4 clinical trials Get access Lisa W M Leung, Leung Department Cardiology, St. George's University Hospitals NHS Foundation Trust, Blackshaw Road, London SW17 0QT, UK Corresponding author. Tel: +44 2087253079; fax: 2087254117. E-mail address:lleung@sgul.ac.uk https://orcid.org/0000-0001-7485-6440 Search other works by this...