The field of 3D face modeling has a large gap between high-end and low-end methods. At the high end, best facial animation is indistinguishable from real humans, but this comes at cost extensive manual labor. low capture consumer depth sensors relies on models that are not expressive enough to variability in natural shape expression. We seek middle ground by learning model thousands accurately aligned scans. Our FLAME (Faces Learned with an Articulated Model Expressions) designed work...

Rendering bridges the gap between 2D vision and 3D scenes by simulating physical process of image formation. By inverting such renderer, one can think a learning approach to infer information from images. However, standard graphics renderers involve fundamental discretization step called rasterization, which prevents rendering be differentiable, hence able learned. Unlike state-of-the-art differentiable renderers, only approximate gradient in back propagation, we propose truly framework that...

We propose a novel approach for 3D video synthesis that is able to represent multi-view recordings of dynamic real-world scene in compact, yet expressive representation enables high-quality view and motion interpolation. Our takes the high quality compactness static neural radiance fields new direction: model-free, setting. At core our time-conditioned field represents dynamics using set compact latent codes. are significantly boost training speed perceptual generated imagery by hierarchical...

Abstract Background Every year around the world, more than 2 million women are diagnosed with breast cancer and genital tract cancers. However, there rare studies comprehensively describing global regional trends of incidence mortality women’s Methods To study burden trend cancers, we conducted this cross-sectional based on epidemiologic data Global Burden Disease 2019. In study, female patients cancer, cervical ovarian uterine worldwide from 1990 to 2019 were involved. The incidence, death,...

Natural Killer (NK) cells, intrinsic to the innate immune system, are pivotal in combating cancer due their independent cytotoxic capabilities antitumor response. Unlike predominant treatments that target T cell immunity, limited success of immunotherapy emphasizes urgency for innovative approaches, with a spotlight on harnessing potential NK cells. Despite tumors adapting mechanisms evade cell-induced cytotoxicity, there is optimism surrounding Chimeric Antigen Receptor (CAR) This...

Female-specific cancers, particularly breast, cervical, ovarian, and uterine account for nearly 40% of all cancers in women. This study aimed to analyze the global epidemiological trends these from 1990 2021, offering insights into their evolving patterns providing valuable information health policymakers allocate healthcare resources more effectively. Data Global Burden Disease Study 2021 (GBD 2021) were used comprehensively assess incidence, mortality, disability-adjusted life years...

Rendering bridges the gap between 2D vision and 3D scenes by simulating physical process of image formation. By inverting such renderer, one can think a learning approach to infer information from images. However, standard graphics renderers involve fundamental discretization step called rasterization, which prevents rendering be differentiable, hence able learned. Unlike state-of-the-art differentiable renderers, only approximate gradient in back propagation, we propose truly framework that...

Rendering is the process of generating 2D images from 3D assets, simulated in a virtual environment, typically with graphics pipeline. By inverting such renderer, one can think learning approach to predict shape an input image. However, standard rendering pipelines involve fundamental discretization step called rasterization, which prevents be differentiable, hence suitable for learning. We present first non-parametric and truly differentiable rasterizer based on silhouettes. Our method...

Abstract Salinity is a major abiotic stress that affects plant growth and development leads to crop yield loss. Many species are more sensitive salinity at the seed germination stage than other developmental stages. Some studies have shown sunflower tolerant certain degree. However, no systematic screening data for germplasms available stress. In this study, 552 with different genetic backgrounds were evaluated salt tolerance. Among them, 30 53 identified as highly salt-tolerant germplasms,...

The phytoalexin resveratrol exhibits anti-tumour activity in many types of cancer. In this study, we showed that suppressed the survival gastric tumour cells both vivo and vitro. Resveratrol promoted apoptosis, autophagy endoplasmic reticulum (ER) stress a dose-dependent manner. RNA-seq analysis multiple cell death signalling pathways were activated after treatment, while use ER activators (tunicamycin thapsigargin) combinatorial with led to further inhibition cancer survival. Results also...

Abstract The programmed cell death 1 (PD-1) signaling pathway, a key player in immune checkpoint regulation, has become focal point cancer immunotherapy. In the context of cancer, upregulated PD-L1 on tumor cells can result T exhaustion and evasion, fostering progression. advent PD-1/PD-L1 inhibitor demonstrated clinical success by unleashing from exhaustion. Nevertheless, challenges such as resistance adverse effects have spurred exploration innovative strategies, with bispecific antibodies...

Background Cervical cancer poses a significant global threat to women’s health. However, current therapeutic interventions, such as radiotherapy, chemotherapy, surgical resection, and immune checkpoint inhibitors, face limitations in the advanced stages of disease. Given immunosuppressive microenvironment cervical cancer, it is imperative explore novel perspectives. In this regard, STING agonists have emerged promising candidates. Methods The expression profiles clinicopathological data were...

Abstract In recent years, the repurposing of conventional and chemotherapeutic drugs is recognized as an alternative strategy for health care. The main purpose this study to strengthen application non‐oncological drug metformin on breast cancer treatment in perspective epigenetics. present study, was found inhibit cell proliferation, promote apoptosis induce cycle arrest cells at a dose‐dependent manner. addition, elevated acH3K9 abundance decreased acH3K18 level. expression lncRNA MALAT1,...

C and Mo in the form of solid solution atom or compound phase is distributed CoCrFeMnNi high entropy alloy (HEA), which have effects strengthening second strengthening. CoCrFeMnNi–Mo5C0.5 HEA were prepared by adding elements to HEA, then heat treatment carried out furnace-cooling, air-cooling water-cooling respectively. microstructure composition as-cast treated examined scanning electron microscopy (SEM), energy dispersive spectrometry (EDS) X-ray diffraction (XRD), mechanical properties...