A5068130741- Atmospheric and Environmental Gas Dynamics
- Spectroscopy and Laser Applications
- Atmospheric Ozone and Climate
- DNA and Nucleic Acid Chemistry
- Chemical Synthesis and Analysis
- Methane Hydrates and Related Phenomena
- Mass Spectrometry Techniques and Applications
- Advanced biosensing and bioanalysis techniques
- Biopolymer Synthesis and Applications
- Plasma Diagnostics and Applications
- Isotope Analysis in Ecology
- Magnetic confinement fusion research
- Advanced Chemical Sensor Technologies
- Plant Physiology and Cultivation Studies
- Atomic and Subatomic Physics Research
- Nuclear Physics and Applications
- Geology and Paleoclimatology Research
- Astro and Planetary Science
- Bacteriophages and microbial interactions
- Agricultural Productivity and Crop Improvement
- Seed and Plant Biochemistry
- Laser-induced spectroscopy and plasma
- Global Energy Security and Policy
- Educational Robotics and Engineering
- Molten salt chemistry and electrochemical processes
Swiss Federal Laboratories for Materials Science and Technology
2022-2025
Heidelberg University
2018-2020
Physikalisch-Technische Bundesanstalt
2020
Sorbonne Université
2019
Université Paris Sciences et Lettres
2019
Centre National de la Recherche Scientifique
2019
Laboratoire d’Etudes du Rayonnement et de la Matière en Astrophysique et Atmosphères
2019
MIREA - Russian Technological University
2018-2019
Moscow State University of Fine Chemical Technologies
2013-2017
Lomonosov Moscow State University
2013-2015
Mid-infrared laser absorption spectroscopy enables rapid and nondestructive analysis of methane clumped isotopes. However, current analytical methods require a sample size 20 mL STP (0.82 mmol) pure CH4 gas, which significantly limits its application to natural samples. To enhance the performance spectroscopic measurement isotopes, we established platform with newly selected spectral windows for isotope analysis: 1076.97 cm–1 12CH2D2 1163.47 13CH3D, custom-built gas inlet system. These were...
Intramolecular or position-specific carbon isotope analysis of propane (13CH3–12CH2–12CH3 and 12CH3–13CH2–12CH3) provides unique insights into its formation mechanism temperature history. The unambiguous detection such isotopic distributions with currently established methods is challenging due to the complexity technique tedious sample preparation. We present a direct nondestructive analytical quantify two singly substituted, terminal (13Ct) central (13Cc), isotopomers, based on quantum...
Abstract Simultaneous analysis of carbon dioxide isotopologues involved in the isotope exchange between doubly substituted 13 C 16 O 18 molecule and 12 2 has become an exciting new tool for geochemical, atmospheric paleoclimatic research with applications ranging from stratospheric chemistry to carbonate-based geothermometry studies. Full exploitation this proxy thermometer is limited due time consuming costly using mass spectrometric instrumentation. Here, we present all optical clumped CO...
Unambiguous detection of the clumped carbon dioxide isotopologue 13C16O18O with isotope ratio mass spectrometry is difficult due to isobaric interference on m/z = 47. We present an analytical technique based direct absorption laser spectroscopy for precise, and simultaneous all isotopologues involved in exchange reaction 12C16O2 + ↔ 12C16O18O 13C16O2 12C16O17O. The achieved precision 2 × 10-5 13C16O18O/13C16O2 12C16O18O/12C16O2 ratios allows equilibrium constant K be determined external...
New polyanionic modifications of polyamide nucleic acid mimics were obtained. Thymine decamers synthesized from respective chiral α- and γ-monomers, their enantiomeric purity was assessed. Here, we present the decamer synthesis, purification characterization by MALDI-TOF mass spectrometry an investigation hybridization properties decamers. We show that modified γ-S-carboxyethyl-T10 PNA forms a stable triplex with polyadenine DNA.
The relative abundance of methane isotopologues offers key insights into the global (CH4) cycle. Advances in laser spectroscopy enable routine high-precision measurements even for rare deuterated isotopologues, 12CH3D and 13CH3D, provided there are sufficiently high amount fractions reproducible measurement conditions, which can be achieved by CH4 adsorption–desorption techniques. We present a new cryogen-free automated preconcentration device─CleanEx─designed quantitative extraction from...
We present a quantum cascade laser-based absorption spectrometer deploying compact (145 mL volume) segmented circular multipass cell (SC-MPC) with 6 m optical path length. This SC-MPC is embedded into an effective cooling system to facilitate operation at cryogenic temperatures. For CO2, the sample cooled 153 K, i.e. close sublimation point 10 mbar. enables efficient suppression of interfering hot-band transitions more abundant isotopic species and thereby enhances analytical precision. As...
The development of fusion energy will require materials resilient to harsh bombardment by energetic plasma. Linear plasma devices are widely used examine such simulating power loads and particle fluxes, which envisaged for the future reactor grade devices. To correctly simulate these conditions, in simulator should be running continuously have high enough density, 1019m-3 or higher. A good candidate produce a is helicon source. This paper reviews source, under collaboration between Budker...
The ion source for along pulse operating diagnostic neutral beam injector has been developed. to form an 8 A, 60 keV hydrogen beam. consists of RF-plasma driver and a four grids ion-optical system. Both system plasma have augmented water-cooling Geometry the was optimized by numerical simulations in order achieve minimal angular divergence. performance developed numerically simulated. Design experimental results are presented paper.
Tunable electromagnetic sources, such as voltage controlled oscillators (VCO), micro electromechanical systems (MEMS) or diode lasers are often required to be linear during frequency-sweep modulation. In many cases, it might also sufficient that the degree of non-linearity can well controlled. Without further efforts, these conditions rarely achieved using free running sources. Based on a pre-distortion ramp, we develop in this letter simple and universal method minimizes non-linear...
Bulk isotope analytical methods of CH4 quantify carbon and hydrogen ratios (δ13C δD) to provide information on the sources sinks in natural environments. A more extensive tracing pathways, especially when multiple processes are involved, has been realized by novel measurements techniques capable methane clumped analysis (termed as Δ13CH3D Δ12CH2D2) during past decade. These paired datasets can either be used proxy for exploring formation temperatures under...
Nitrous oxide (N2O), a greenhouse gas and ozone-depleting molecule with 116-year atmospheric lifetime, is accumulating in the atmosphere at an accelerating pace. While it known that conversion of anthropogenic nitrogen pollutants to N2O by environmental cycle predominately drives this accumulation, essential questions remain regarding spatial temporal balance production consumption. Stable isotope measurements δ15N, δ18O, 15N site preference (SP) provide valuable...
One of the major challenges facing modern biochemical and biomedical technologies are finding molecular tools for diagnosis detection genetic diseases. In this connection, several classes oligonucleotides have been developed that can recognize bind to DNA RNA with high affinity sequence selectivity withstand enzymatic degradation by proteases nucleases; however, few traverse cell membrane on their own. such promising class nucleic acid mimics in last two decades which showed good results...
Currently, peptide nucleic acids (PNAs) play an important role as therapeutic agents, molecular tools for diagnosis and detection of genetic diseases well in biosensor probes. This research aims to optimize the synthesis aeg- γ-(S)-Me PNA monomers based on L-Ala, intended oligomerization according Boc protocol. The were obtained through condensation corresponding pseudopeptides with carboxymethyl purine bases. During work, optimization benzyloxycarbonyl- N6-adenine-9-yl-acetic acid...
<p>Clumped isotope thermometry deals with the relative abundance of molecules that contain more than one rare isotopes. For methane, <sup>13</sup>CH<sub>3</sub>D and <sup>12</sup>CH<sub>2</sub>D<sub>2</sub> isotopologues have been recently proposed as promising tracers in geological, biogeochemical, atmospheric studies. Their denoted...
<p>Mid-infrared optical absorption spectroscopy techniques, in particular with quantum cascade lasers (QCLs), allow realization of highly sensitive and compact spectrometers for the detection greenhouse gases such as carbon dioxide its stable isotopes [1]. Clumped isotope analysis is evolving into an established method environmental, geological, biogeochemical research. Optical clumped thermometry was recently demonstrated...
The FAIR synchrotron SIS 100 will be operated with high-intensity proton and heavy-ion beams. collimation system should prevent beam loss induced degradation of the vacuum, activation accelerator structure magnet quenches. A conventional two-stage betatron is considered for operation protons fully-stripped ions. Particle tracking ion-collimator interaction simulations were performed. angular momentum distributions scattered halo particles described using analytical models numerical tools...