A5037159681- Immunotherapy and Immune Responses
- Cancer Immunotherapy and Biomarkers
- Immune Cell Function and Interaction
- SARS-CoV-2 and COVID-19 Research
- Xenotransplantation and immune response
- Ferroptosis and cancer prognosis
- Immune responses and vaccinations
- COVID-19 epidemiological studies
- Infection Control and Ventilation
- Immune cells in cancer
- RNA Interference and Gene Delivery
Ministry of Health of the Russian Federation
2019-2024
Особенности клеточного иммунитета медицинских работников в первую волну пандемии SARS
Introduction. The increasing clinical use of cellular technologies suggests the possibility long-term storage product while maintaining its viability and basic properties. procedures cell’s cryopreservation used in laboratory as well practice differ a lot. Each method includes two tasks to solve: what is optimal freezing medium procedure prefer. In this paper, we present utilized our center for bone marrow cell cryopreservation. was carried out nitrogen vapor after adding containing 95 %...
Background. The tumor microenvironment can both restrain growth and promote disease progression. Therefore, the study of tumor-infiltrating lymphocytes (TILs) subpopulation composition is an urgent significant topic. Aim. To characterize immune renal cancer by flow cytometry. Materials methods. included blood, kidney normal tissue removed 32 patients with clear cell treated at N. Blokhin National Medical Research Center Oncology. Kidney was obtained during surgical removal (resection /...
Despite the success in early diagnosis and drug treatment of breast cancer patients, long-term results are still unsatisfactory, this regard, role research aimed at studying various mechanisms development disease is increasing. It has been established that degree tumor infiltration by immune cells their composition directly related to response therapy. Multiparameter flow cytometry (PC) allows studies subpopulation TILs. The aim work was study features lymphoid microenvironment (TILs) tumors...
Иммунная система является одной из основных систем гомеостаза. Только иммунная способна отличать «свое» от «чужого» и обеспечивать защиту организма чужеродных агентов, включая патогенные микроорганизмы клетки злокачественных опухолей. На существование эндогенного контроля роста опухолей указывают случаи спонтанной регрессии Спонтанная регрессия рака определяется как полное или частичное исчезновение злокачественнойопухоли при отсутствии терапии, способной вызвать противоопухолевый эффект,...
Background . The incidence of oral mucosa cancer (OMC) is higher in people over 50 years age, and the aggressiveness course disease under age. In this context, it interest to clarify mechanisms immune disorders characteristic patients different age groups. Aim To research systemic local immunity OMC relationship peripheral blood lymphocyte population (PBLs) tumor infiltrating lymphocytes (TILs) with patient’s sex Materials methods PBLs TILs effector suppressor populations were studied by...