A5029969939- Reproductive Physiology in Livestock
- Microbial infections and disease research
- Milk Quality and Mastitis in Dairy Cows
- Diet and metabolism studies
- Adipose Tissue and Metabolism
- Metabolism, Diabetes, and Cancer
- Coccidia and coccidiosis research
- Nuts composition and effects
- Cancer Diagnosis and Treatment
- Pregnancy and Medication Impact
- Pelvic and Acetabular Injuries
- Ginger and Zingiberaceae research
- Soft tissue tumors and treatment
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Methemoglobinemia and Tumor Lysis Syndrome
- Natural Compounds in Disease Treatment
- Fatty Acid Research and Health
- Bone Metabolism and Diseases
- Digestive system and related health
- Heme Oxygenase-1 and Carbon Monoxide
- Selenium in Biological Systems
- Immune cells in cancer
- Bone fractures and treatments
- Bone Tumor Diagnosis and Treatments
- Liver Disease Diagnosis and Treatment
Jilin University
2011-2015
Jilin Medical University
2014-2015
Alzheimer's disease is a neurodegenerative disorder associated with the deposition of peptide amyloid-beta (Aβ) in senile plaques and cerebral vasculature. The neurotoxic mechanisms this condition have been linked to oxidative-stress-induced apoptosis leading widespread neuronal loss. Herein, we demonstrate neuroprotective effects ketone body D-β-hydroxybutyrate (β-HB) neural cell lines an animal model induced by injecting Aβ into hippocampus. Using histological examination TUNEL assay, show...
The objective of this study was to test the hypothesis that p-cymene can attenuate acute lung injury induced by lipopolysaccharide (LPS) in vivo. In mouse model LPS-induced injury, intraperitoneal preconditioning with resulted a significant reduction pro-inflammatory cytokines (TNF-α, IL-1β and IL-6), water gain, inflammatory cell infiltration, tissue myeloperoxidase activity. addition, blocked phosphorylation IκBα protein mitogen-activated kinases (MAPK) signaling pathway activation....
8-Gingerol is one of the principal components ginger, which widely used in China and elsewhere as a food, spice herb. It shows immunosuppressive activity on immune responses to ovalbumin (OVA) mice. In present study, we found that 8-gingerol suppressed lipopolysaccharide (LPS) concanavalin A (ConA)-stimulated splenocyte proliferation vitro. vivo, not only significantly Con A-, LPS- OVA-induced (P < 0.05) but also decreased percentage CD19+ B cells CD3+ T cell at high doses (50, 100 mg/kg)....
The administration of exogenous β-hydroxybutyrate (β-HB), as well fasting and caloric restriction, is a condition associated with β-HB abundance decreased appetite in animals. Increased exist simultaneously some diseases, such bovine left displaced abomasums (LDA) human chronic gastritis. However, the effects on stomach injuries have not been explored. To elucidate possible stomach, mice were injected intraperitoneally β-HB, abomasum smooth muscle cells (BSMCs) treated different...
We sought to elucidate the effects of different concentrations dietary selenium on calcium ion release, MLCK levels, and muscle contraction in uterine smooth rats. The (Se) content blood tissues was detected by fluorescence spectrophotometry. Ca(2+) measured atomic absorption spectroscopy. Calmodulin (CaM) RNA protein levels were analyzed quantitative real-time polymerase chain reaction Western blot, respectively. Dietary Se intake increased concentration tissues. addition also promoted CaM...
Increased blood non-esterified fatty acid (NEFA) concentrations might be implicated as a factor that plays role in the pathogenesis of gastrointestinal motility disorder, such abomasal displacement. We sought to elucidate possible effects high NEFA on primary cultured bovine smooth muscle cells (BSMC). BSMC treated with resulted decrease cell viability and increase apoptosis rate. treatment induced oxidative stress, revealed by increased levels ROS MDA, while decreased antioxidative...