A5009940107- Lipoproteins and Cardiovascular Health
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cancer, Lipids, and Metabolism
- Lipid metabolism and disorders
- Cholesterol and Lipid Metabolism
- Diet and metabolism studies
- Nutritional Studies and Diet
- Liver Disease Diagnosis and Treatment
- Obesity, Physical Activity, Diet
- Fatty Acid Research and Health
- Peroxisome Proliferator-Activated Receptors
- Diabetes Management and Education
- Nutrition, Genetics, and Disease
- Advanced Glycation End Products research
- Diet, Metabolism, and Disease
- Muscle metabolism and nutrition
- Health and Lifestyle Studies
- COVID-19 Clinical Research Studies
- Adipokines, Inflammation, and Metabolic Diseases
- Nutrition and Health in Aging
- Food composition and properties
- Adipose Tissue and Metabolism
- Biomedical and Engineering Education
- Cancer, Hypoxia, and Metabolism
- Global Public Health Policies and Epidemiology
Hospital Universitario Miguel Servet
2015-2024
Universidad de Zaragoza
2014-2024
Instituto de Investigación Sanitaria Aragón
2015-2024
Centro de Investigación en Red en Enfermedades Cardiovasculares
2017-2024
Centro de Investigación Biomédica en Red
2018-2024
Instituto de Salud Carlos III
2020-2022
Fundacion Agencia Aragonesa para la Investigacion y el Desarrollo
2018
Instituto Aragonés de Ciencias de la Salud
2014
apo (apolipoprotein) E has crucial role in lipid metabolism. The genetic variation APOE gene is associated with monogenic disorders and contributes to polygenic hypercholesterolemia interindividual variability cholesterol. rare variants may be involved the phenotype of hyperlipidemias.Exon 4 were sequenced all consecutive unrelated subjects primary hyperlipidemia from a Lipid Unit (n=3667) 822 random Aragon Workers Health Study. Binding affinity VLDL (very low-density lipoprotein) LDL...
Game-based learning (GBL) is effective for increasing participation, creativity, and student motivation. However, the discriminative value of GBL knowledge acquisition has not yet been proven. The aim this study to assess Kahoot! as a tool formative assessment in medical education two different subjects.
The majority of hypertriglyceridemias are diagnosed as familial combined hyperlipidemia (FCHL) and primary isolated hypertriglyceridemias. contribution common genetic variants in the difference between FCHL have not been thoroughly examined.This study involved 580 patients with 403 controls. Of 37 single nucleotide polymorphisms examined, 12 located 10 genes showed allelic genotype frequency differences minor alleles APOE, APOA5, GALNTN2, GCKR were positively correlated plasma triglycerides,...
The aim of our study was to investigate a large cohort overweight subjects consuming homogeneous diet identify the genetic factors associated with weight loss that could be used as predictive markers in interventions. We retrospectively recruited (N = 788) aged over 18 years Body Mass Index (BMI) between 25 and 40 kg/m2 who were treated at lipid unit for least one year from 2008 2016, we also control group (168 patients) normal BMIs. All participants received counselling nutritionist...
Abstract Background Lipoprotein(a) (Lp(a)) is a significant cardiovascular risk factor. Knowing the mechanisms that regulate its concentration can facilitate development of Lp(a)-lowering drugs. This study analyzes relationship between triglycerides (TGs) and Lp(a) concentrations, cross-sectionally longitudinally, influence number composition TG-rich lipoproteins, APOE genotype. Methods Data from Aragon Workers Health Study (AWHS) (n = 5467), National Nutrition Examination Survey III phase 2...
The association between APOE genotypes and cardiovascular disease (CVD) is partially mediated by LDL-cholesterol concentration but persists after adjusting for lipid levels other risk factors. Data from the Aragon Workers Health Study (AWHS) (n = 4159) Lipid Unit at Hospital Universitario Miguel Servet (HUMS) 3705) were used to investigate relationship C-reactive protein (CRP) genotype. Lipoprotein particle GlycA concentrations analyzed in a subsample AWHS. genotyping was carried out Sanger...
Hypertriglyceridemia (HTG) is a common complex metabolic trait that results of the accumulation relatively genetic variants in combination with other modifier genes and environmental factors resulting increased plasma triglyceride (TG) levels. The majority severe primary hypertriglyceridemias diagnosed adulthood their molecular bases have not been fully defined yet. prevalence HTG highly variable among populations, possibly caused by differences background. However, very high TG frequency...
Neurophobia is defined as the fear of neural sciences and clinical neurology that due to students' inability apply their knowledge basic situations. This phenomenon, well documented in Anglosphere, has seldom been studied other European countries never our country. Our study aimed determine whether said existed among Spanish medical students.