A5078554476- Probiotics and Fermented Foods
- Pediatric health and respiratory diseases
- Immune Response and Inflammation
- Pneumonia and Respiratory Infections
- Gut microbiota and health
- Viral gastroenteritis research and epidemiology
- Infant Nutrition and Health
- Respiratory viral infections research
- Antimicrobial Peptides and Activities
- Clostridium difficile and Clostridium perfringens research
- Escherichia coli research studies
- Bacterial Infections and Vaccines
- Digestive system and related health
- Influenza Virus Research Studies
- Microbial Metabolites in Food Biotechnology
- Clinical Nutrition and Gastroenterology
- Bacteriophages and microbial interactions
- Streptococcal Infections and Treatments
- Immune Cell Function and Interaction
- Diabetes and associated disorders
- Infant Health and Development
- Helicobacter pylori-related gastroenterology studies
- Biochemical Analysis and Sensing Techniques
- Animal Virus Infections Studies
- Neutropenia and Cancer Infections
National University of Tucumán
2013-2024
Centro Científico Tecnológico - Tucumán
2010-2024
Consejo Nacional de Investigaciones Científicas y Técnicas
2014-2023
Universidade de Vigo
2019
Centro Nacional de Investigaciones Científicas
2002
Nestlé (Switzerland)
1999-2001
Centro de Investigación y Desarrollo en Criotecnología de Alimentos
1999
Instituto de Química y Fisicoquímica Biológicas
1995
Instituto Nacional de Higiene, Epidemiología y Microbiología
1995
University of Buenos Aires
1990
The effect of perorally (p.o) administered Lactobacillus casei and L. bulgaricus on macrophage activation in mice was studied. were p.o. to for 8 days. measured days 2, 3, 5, lactobacillus administration by using biochemical functional criteria. We the release lysosomal hydrolases, level a nonlysosomal enzyme, vitro phagocytic activity mouse peritoneal macrophages. All assays performed comparatively with inoculated (viable nonviable cells) intraperitoneally (i.p.) at same dose as...
Abstract Background Some studies have shown that nasally administered immunobiotics had the potential to improve outcome of influenza virus infection. However, capacity protection against respiratory syncytial (RSV) infection was not investigated before. Objective The aims this study were: a) evaluate whether nasal administration Lactobacillus rhamnosus CRL1505 (Lr05) and L. CRL1506 (Lr06) are able antiviral defenses beneficially modulate immune response triggered by TLR3/RIG-I activation;...
Corynebacterium pseudodiphtheriticum is a Gram-positive bacterium found as member of the normal microbiota upper respiratory tract. It was suggested that C. may be potentially used next-generation probiotic for nasal application, although no deep studies were performed in this regard. We hypothesized human isolate strain 090104 able to modulate innate immune response and beneficially influence resistance viral bacterial infections. Therefore, present study we investigated how exposure infant...
Some studies have shown that probiotics, including Lactobacillus rhamnosus CRL1505, had the potential to beneficially modulate outcome of certain bacterial and viral respiratory infections. However, these did not determine mechanism(s) by which probiotics contribute host defense against viruses. In this work we demonstrated orally administered CRL1505 (Lr1505) was able increase levels IFN-γ, IL-10 IL-6 in tract number lung CD3+CD4+IFN-γ+ T cells. To mimic pro-inflammatory physiopathological...
Summary Lactobacilli, often used as effectors of host functions, could play an important role in maintaining human health by controlling other intestinal microorganisms capable producing harmful effects. Using experimental model, we studied the effect different oral doses Lactobacillus casei on secretory IgA response and protective capacity microorganism preventing infections. The optimization dose Lb. previous feeding use lactobacillus immunological way to control enteric infections were...
Summary The protective effect of feeding milk fermented with a mixture Lactobacillus casei sp. and Lb. acidophilus against Salmonella typhimurium infection in mice was compared that obtained milks these microorganisms individually. survival rate after oral Sal. 100% pretreated by during 8 d the milks. Similar treatments individual were ineffective. Moreover, became more susceptible to such treatment. colonization liver spleen pathogen markedly inhibited pretreatment milk, while inhibition...
ABSTRACT Previously, we demonstrated that Lactobacillus jensenii TL2937 attenuates the inflammatory response triggered by activation of Toll-like receptor 4 (TLR-4) in porcine intestinal epithelial cells. In view critical importance antigen-presenting cell (APC) polarization immunoregulation, objective present study was to examine effect strain on patterns APCs from swine Peyer's patches (PPs). We direct exposure L. absence signals increased expression interleukin-10 (IL-10) and transforming...
Several research works have demonstrated that beneficial microbes with the capacity to modulate mucosal immune system (immunobiotics) are an interesting alternative improve outcome of bacterial and viral respiratory infections. Among immunobiotic strains beneficially immunity, Lactobacillus rhamnosus CRL1505 has outstanding properties. Although we significantly advanced in demonstrating L. resistance against infections as well cellular molecular mechanisms involved its activities, potential...
Previous findings suggested that Lactobacillus rhamnosus CRL1505 is able to increase resistance of children intestinal viral infections. However, the cells, cytokines and receptors involved in immunoregulatory effect this probiotic strain have not been fully characterized. We aimed gain insight into mechanisms immunomodulatory therefore evaluated vitro crosstalk between L. CRL1505, porcine epithelial cells (IECs) antigen presenting (APCs) from swine Peyer's patches order deepen our knowledge...
Lactobacillus fermentum UCO-979C, a strain isolated from human stomach, was previously characterized by its potential probiotic properties. The UCO-979C displayed the ability to beneficially regulate innate immune response triggered Helicobacter pylori infection in gastric epithelial cells. In this work, we conducted further vitro studies intestinal cells and vivo experiments mice order characterize immunomodulatory effects of L. on mucosa. Results demonstrated that is capable differentially...
Lactobacillus rhamnosus CRL1505, a strain of goats' milk origin, is able to stimulate mucosal immunity and protect immunocompetent mice from intestinal respiratory infections.In this work we developed characterized fermented containing L. demonstrated in model immunosuppression that the final dairy product preserves immunomodulatory properties strain. CRL1505 survived manufacturing process maintained viability 10(6) cfu g(-1) during storage. The was accepted by 90.48% panelists considered as...