Lee Solbay Agudelo-Gómez

ORCID: 0000-0002-9733-3420
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About
Contact & Profiles
Research Areas
  • Essential Oils and Antimicrobial Activity
  • Phytochemical compounds biological activities
  • Natural product bioactivities and synthesis
  • Biological Activity of Diterpenoids and Biflavonoids
  • Herpesvirus Infections and Treatments
  • Chemical Synthesis and Analysis
  • Synthesis and biological activity
  • Phytochemistry and Biological Activities
  • HIV/AIDS drug development and treatment
  • Plant biochemistry and biosynthesis
  • Antibiotics Pharmacokinetics and Efficacy
  • Toxin Mechanisms and Immunotoxins
  • Plant chemical constituents analysis
  • Click Chemistry and Applications
  • Insect Pest Control Strategies
  • Advancements in Transdermal Drug Delivery
  • Multicomponent Synthesis of Heterocycles
  • Bioactive Natural Diterpenoids Research
  • Fern and Epiphyte Biology
  • Bee Products Chemical Analysis

Universidad de Antioquia
2009-2015

The syntheses of combretastatin A-4 from gallic acid and three combretastatin-based hybrids are described. Starting commercial acid, the phosphonium salt (3,4,5-trimethoxybenzylphosphonium bromide) is synthesized coupled, through a Wittig reaction, with several aldehydes, including methoxymethyl-protected isovanillin, aldehyde y-bicyclohomofarnesal having labdane skeleton, 3-(3-pyridyl) propanal, furfural. biological properties cis-coupled compounds as cytotoxic, antiviral antifungal agents...

10.1177/1934578x1200700822 article EN Natural Product Communications 2012-08-01
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