Ilgaz Taştekil

ORCID: 0000-0002-9737-5727
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About
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Research Areas
  • Protein Interaction Studies and Fluorescence Analysis
  • Lipid Membrane Structure and Behavior
  • Monoclonal and Polyclonal Antibodies Research
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Immune Cell Function and Interaction
  • Antibiotics Pharmacokinetics and Efficacy
  • Enzyme Structure and Function
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Viral-associated cancers and disorders
  • Enzyme-mediated dye degradation
  • Protein purification and stability
  • 3D Printing in Biomedical Research
  • Effects and risks of endocrine disrupting chemicals
  • Proteins in Food Systems
  • Enzyme Catalysis and Immobilization
  • Antibiotic Resistance in Bacteria

Pharmaceutical Biotechnology (Czechia)
2024-2025

Sağlık Bilimleri Üniversitesi
2024-2025

Marmara University
2022-2025

University of Health Science
2023

Abstract This study investigates the binding affinity and interaction mechanism of chlorhexidine (CHX), a commonly used antimicrobial agent, with lysozyme (L ZM ), crucial salivary enzyme in oral cavity. Chicken egg white (CEWL ) was as model L . Tri‐ N ‐acetylchitotriose (NAG 3 applied redocking analysis to determine exact sites CEWL The elucidates how CHX interacts at molecular level, employing surface plasmon resonance (SPR), docking, dynamics (MD) simulations. SPR revealed that an...

10.1002/slct.202405476 article EN ChemistrySelect 2025-02-01

Abstract Lysozyme (L ZM ) is an important enzyme in medicine and industry. Tannic acid (TA) used brewing, wine industry, as a food flavor enhancer. In nutritional science, L interacts with TA, notably saliva. This study aimed to investigate the binding interaction between TA using surface plasmon resonance, molecular docking, dynamics simulation. Chicken egg white lysozyme (CEWL was applied model protein. Tri‐N‐acetylchitotriose (NAG 3 ), known inhibitor of CEWL , redocking experiments...

10.1002/fsn3.4315 article EN cc-by Food Science & Nutrition 2024-07-22

Abstract In this study, the binding behavior of β‐sitosterol with lysozyme (L ZM ) was elucidated by surface plasmon resonance (SPR), computational molecular docking and dynamics simulation studies. Chicken egg white (CEWL served as a model protein. Tri‐N‐acetylchitotriose (NAG 3 used in redocking experiments to generate precise location displayed slightly better energy (−6.68±0.04 kcal/mol) compared NAG . Further simulations MMPBSA analysis revealed that residues Glu35, Gln57‐Asn59, Trp62,...

10.1002/cbdv.202401470 article EN Chemistry & Biodiversity 2024-10-07

Lysozyme (LZM) is a crucial enzyme in both medical and industrial applications. It found body fluids, used as food ingredient, plays role the wine-making process. In nutritional science industry, LZM frequently interacts with tannic acid (TA), particularly context of wine production saliva. TA, polyphenol-based substance, commonly employed clarifying agent brewing industries flavor enhancer various products. this study, we investigated interaction between TA through combination computational...

10.2139/ssrn.4651645 preprint EN 2023-01-01
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