A5071927696- Respiratory viral infections research
- SARS-CoV-2 and COVID-19 Research
- Viral Infections and Immunology Research
- Immunodeficiency and Autoimmune Disorders
- Tracheal and airway disorders
- Effects and risks of endocrine disrupting chemicals
Massachusetts General Hospital
2023-2024
United States Department of Health and Human Services
2022
Harvard University
2021
Parental preconception exposure to select phenols and phthalates was previously associated with increased risk of preterm birth in single chemical analyses. However, the joint effect phenol phthalate mixtures on is unknown. We included 384 female 211 male (203 couples) participants seeking infertility treatment Environment Reproductive Health (EARTH) Study who gave singleton infants between 2005 2018. Mean urinary concentrations bisphenol A (BPA), parabens, eleven biomarkers, including...
Although young children generally experience mild symptoms following infection with SARS-CoV-2, severe acute and long-term complications can occur. SARS-CoV-2 mRNA vaccines elicit robust immunoglobulin profiles in ages 5 years older, adults, corresponding substantial protection against hospitalizations disease. Whether similar immune responses humoral be observed vaccinated infants children, who have a developing vulnerable system, remains poorly understood. To study the impact of...
Understanding antibody responses to SARS-CoV-2 vaccination is crucial for refining COVID-19 immunization strategies. Generation of mucosal immune responses, including IgA, could be potential benefit vaccine efficacy, yet limited evidence exists regarding the production antibodies following administration current mRNA vaccines young children.
Abstract Background Understanding antibody responses to SARS-CoV-2 vaccination is crucial for refining COVID-19 immunization strategies. Generation of mucosal immune responses, including IgA, could be potential benefit vaccine efficacy; however, limited evidence exists regarding the production antibodies following administration current mRNA vaccines young children. Methods We measured levels against from a cohort children under 5 years age (n = 24) undergoing (serially collected, matched...
Although parental preconception exposure to some phenols and phthalates have been associated with reduced birthweight, few studies examined these chemicals as complex mixtures.We included 384 mothers 211 fathers (203 couples) who gave birth singletons from a prospective cohort of couples seeking fertility evaluation. Urinary concentrations bisphenol A (BPA), parabens, 11 phthalate metabolites including those di(2-ethylhexyl) (DEHP) were examined. Birthweight was abstracted delivery records....
Abstract Although young children generally experience mild symptoms following infection with SARS-CoV-2, severe acute and long-term complications can occur. SARS-CoV-2 mRNA vaccines elicit robust immunoglobulin profiles in ages 5 years older, adults, corresponding substantial protection against hospitalizations disease. Whether similar immune responses humoral be observed vaccinated infants children, who have a developing vulnerable system, remains poorly understood. To study the impact of...