A5084778211- Functional Brain Connectivity Studies
- Advanced Neuroimaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Retinal Development and Disorders
- Hip disorders and treatments
- Orthopaedic implants and arthroplasty
- Pain Management and Placebo Effect
- Pain Mechanisms and Treatments
- Retinal Imaging and Analysis
- Total Knee Arthroplasty Outcomes
- Hypothalamic control of reproductive hormones
- Psychosomatic Disorders and Their Treatments
- Retinal Diseases and Treatments
- Bone fractures and treatments
- Neural dynamics and brain function
- Neural and Behavioral Psychology Studies
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Visual perception and processing mechanisms
- Transcranial Magnetic Stimulation Studies
- Cardiac Imaging and Diagnostics
- Atomic and Subatomic Physics Research
- Forensic Anthropology and Bioarchaeology Studies
- Advanced X-ray and CT Imaging
- Pediatric Pain Management Techniques
- Mental Health Research Topics
University of Würzburg
2025
Medical University of Vienna
2015-2024
The University of Texas Southwestern Medical Center
2022
Walton Centre
2022
University of Liverpool
2022
Centre for Biomedical Engineering and Physics
2014
Abbott (Sweden)
2011
Significance Empathy is of major importance for everyday social interaction. Recent neuroscientific models suggest that pain empathy relies on the activation brain areas are also engaged during first-hand experience pain. These rely rather unspecific and correlational evidence. Here, we show inducing analgesia reduces empathy, this associated with decreased empathy-related areas. We then document blocking placebo via an opioid antagonist blocks effects empathy. This finding suggests grounded...
The anticipation of favourable or unfavourable events is a key component in our daily life. However, the temporal dynamics processes relation to brain activation are still not fully understood. A modified version monetary incentive delay task was administered during separate functional magnetic resonance imaging (fMRI) and electroencephalogram (EEG) sessions same 25 participants assess anticipatory with multi-modal neuroimaging set-up. During fMRI, gain loss were both associated heightened...
Recent behavioral investigations suggest that acute stress can increase prosocial behavior. Here, we investigated whether increased empathy represents a potential mechanism for this finding. Using functional magnetic resonance imaging, assessed the effects of on neural responses related to automatic and regulatory components pain as well subsequent Stress activation in brain areas associated with sharing others' pain, such anterior insula, midcingulate cortex, primary somatosensory cortex....
Biological causes underpinning the well known gender dimorphisms in human behavior, cognition, and emotion have received increased attention recent years. The advent of diffusion-weighted magnetic resonance imaging has permitted investigation white matter microstructure unprecedented detail. Here, we aimed to study potential influences biological sex, identity, sex hormones, sexual orientation on by investigating transsexuals healthy controls using diffusion tensor (DTI). Twenty-three...
Abstract Objectives: Anticipatory processes prepare the organism for upcoming experiences. The aim of this study was to investigate neural responses related anticipation and processing painful stimuli occurring with different levels uncertainty. Experimental design: Twenty‐five participants (13 females) took part in an electroencephalography functional magnetic resonance imaging (fMRI) experiment at separate times. A visual cue announced occurrence electrical or nonpainful stimulus,...
Although previous investigations of transsexual people have focused on regional brain alterations, evaluations a network level, especially those structural in nature, are largely missing. Therefore, we investigated the connectome 23 female-to-male (FtM) and 21 male-to-female (MtF) transgender patients before hormone therapy as compared with 25 female male healthy controls. Graph theoretical analysis whole-brain probabilistic tractography networks (adjusted for differences intracranial...
Hip dysplasia (HD) leads to premature osteoarthritis. Timely detection and correction of HD has been shown improve pain, functional status, hip longevity. Several time-consuming radiological measurements are currently used confirm HD. An artificial intelligence (AI) software named HIPPO automatically locates anatomical landmarks on anteroposterior pelvis radiographs performs the needed measurements. The primary aim this study was assess reliability tool as compared multi-reader evaluation in...
The morphometry of the hip and pelvis can be evaluated in native radiographs. Artificial-intelligence-assisted analyses provide objective, accurate, reproducible results. This study investigates performance an artificial intelligence (AI)-based software using deep learning algorithms to measure radiological parameters that identify femoroacetabular impingement dysplasia. Sixty-two radiographs (124 hips) were manually by three observers fully automated performed AI-driven (HIPPO™, ImageBiopsy...
The aim of this study was to investigate the performance an artificial intelligence (AI)-based software for fully automated analysis leg alignment pre- and postoperatively after high tibial osteotomy (HTO) on long-leg radiographs (LLRs).Long-leg 95 patients with varus malalignment that underwent medial open-wedge HTO were analyzed postoperatively. Three investigators AI using deep learning algorithms (LAMA™, ImageBiopsy Lab, Vienna, Austria) evaluated hip-knee-ankle angle (HKA), mechanical...
Abstract Although the sex steroid hormone testosterone is integrally involved in development of language processing, ethical considerations mostly limit investigations to single administrations. To circumvent this issue we assessed influence continuous high‐dose application adult female‐to‐male transsexuals. Subjects underwent magnetic resonance imaging before and after 4 weeks treatment, with each scan including structural, diffusion weighted functional imaging. Voxel‐based morphometry...
It is not known how specific the neural mechanisms underpinning empathy for different domains are. In present study, we set out to test whether shared representations between first-hand pain and are pain-specific or extend unpleasant affective touch as well. Using functional magnetic resonance imaging psychopharmacological experiments, investigated if placebo analgesia reduces empathic experiences of touch, compared them with effects on pain. Placebo also affected experience implicating...
Diffusion-weighted imaging (DWI) is used to measure gray matter tissue density and white fiber organization/directionality. Recent studies show that DWI also allows for assessing neuroplastic adaptations in the human hypothalamus. To this end, we investigated a potential influence of testosterone replacement therapy on hypothalamic microstructure female-to-male (FtM) transgender individuals. 25 FtMs were measured at baseline, 4 weeks, months past treatment start compared female male...
The present study describes retinotopic mapping of the primary visual cortex using functional MRI (fMRI) in patients with retinal disease. It addresses relationship between fMRI data and obtained by conventional assessment including microperimetry (MP) structural imaging.Initial testing involved eight central disease (Stargardt disease, STGD) peripheral (retinitis pigmentosa, RP), who were examined MP (Nidek MP-1). All had a secure clinical diagnosis supported electrophysiological data. used...
Abstract Artificial-intelligence (AI) allows large-scale analyses of long-leg-radiographs (LLRs). We used this technology to derive an update for the classical regression formulae by Trotter and Gleser, which are frequently infer stature based on long-bone measurements. analyzed calibrated, standing LLRs from 4200 participants taken between 2015 2020. Automated landmark placement was conducted using AI-algorithm LAMA™ measurements were determine femoral, tibial total leg-length. Linear...