A5088372071- Skin Protection and Aging
- Osteoarthritis Treatment and Mechanisms
- Enzyme-mediated dye degradation
- Seed Germination and Physiology
- Bone Metabolism and Diseases
- Natural Antidiabetic Agents Studies
- Protein Hydrolysis and Bioactive Peptides
- Inflammatory mediators and NSAID effects
- Enzyme Catalysis and Immobilization
- Protease and Inhibitor Mechanisms
- Wound Healing and Treatments
- Dyeing and Modifying Textile Fibers
- Dye analysis and toxicity
- Glycosylation and Glycoproteins Research
- Pomegranate: compositions and health benefits
- Aldose Reductase and Taurine
- Plant Genetic and Mutation Studies
- Bone and Dental Protein Studies
- Spectroscopy and Chemometric Analyses
- Proteoglycans and glycosaminoglycans research
- bioluminescence and chemiluminescence research
- Polysaccharides and Plant Cell Walls
- Silk-based biomaterials and applications
- Electrochemical sensors and biosensors
- Phytochemistry Medicinal Plant Applications
Universitatea Națională de Știință și Tehnologie Politehnica București
2011-2012
Bristol Royal Infirmary
1983
University of Bristol
1983
Keratin biomaterials with high molecular weights were intensively investigated but few are marketed due to complex methods of extraction and preparation limited understanding their influence on cells behavior. In this context the aim research was elucidate decisive factors for skin homeostasis restoration induced by two low weight keratin hydrolysates extracted conditioned through a simple green method. Two 3758 12,400 Da physico-chemically characterized structure assessed circular dichroism...
The inflammatory, degenerative and rheumatic diseases are triggered evolving at osteoarticular level due to the disruption of functionality constitutive cells extracellular microenvironment correlated with systemic responses as synthesis progressively degradative cytokines.Objectives.The in vitro bioactive efficacy standardized small sea fish extract has therapeutic relevance on strength optimal physiological structural biologic system rendered by primary isolated from human cartilage (HCH,...
Transition to organic farming requires the development of new methods protect seeds from adverse factors. The germinative process and post-germinative phase are strictly controlled by oxidative balance involving lipid peroxidation, reactive oxygen species enzymes activity, directing plant viability its further development. We focus our studies mainly on protection fortification through natural solutions based marigold fenugreek extracts, steroid alkaloids tomatoes hydrolyzed proteins derived...
Polysaccharide material was found in the proteolysis glycopolypeptide fraction from normal human gastric mucus. The polysaccharide identified by carbohydrate and amino acid analyses, elemental analysis its behaviour on density-gradient ultracentrifugation. is polydisperse with a weight-average molecular mass of 300 000 Da. Over 85% consists galactose, this represents 26% all galactose present fractions after beta-elimination reduction material.
Since the constant use of traditional pesticides can have long-term adverse effects on human health, environment and fact that pests develop resistance to them, it is interest natural alternatives with a role protect plants crops. Such an alternative would be phytochemical compounds, antioxidant role, found in fenugreek seeds. This research paper aimed evaluate effect three types extracts obtained from seeds (Trigonella foenum-graecum) radish through germination bioassay. The were different...
Currently, the treatment of wounds is still a challenge for healthcare professionals due to high complication incidences and social impacts, development biocompatible efficient medicines remains goal. In this regard, mesoporous materials loaded with bioactive compounds from natural extracts have potential wound their nontoxicity, loading capacity slow drug release. MCM-41-type material was synthesized by using sodium trisilicate as silica source at room temperature normal pressure. The...
The purpose of this work was to prove the enrichment sunflower oil with active principles (polyphenolic acids, flavones, flavonoids) from plants, using ultrasounds-assisted extraction (UAE) process.The analytical technique used for qualitative characterization UAE samples is thin layer chromatography (TLC), a relatively simple technique, which under certain separation and detection conditions highlights bioactive components plants studied in our study.UV-VIS spectrophotometry evaluate level...
The aim of the present study was to obtain a protein fraction rich in enzymes with proteolytic activity such as serine proteases, chymotrypsins and cysteine proteases investigate preliminary pharmacological effects therapeutic potential osteoarticular diseases. processing marine raw material by applying established optimized sequences operations (selective precipitation followed fractionation FPLC) led well-defined fractions enzymes. To evaluate biological effect isolated polypeptide...
Osteoarthritis (OA) as a multi-factorial disease that features interrelated mechanisms (senescence/ apoptosis, proliferation, decreased synthesis of matrix proteins, activation degrading enzymes, inflammation) and diversity cells involved in bone cartilage metabolism: chondrocytes, osteoblasts, osteoclasts etc. A complete pharmaceutical solution remains an unsolved question this interdisciplinary field research.We focused our approach on osteoarthritic primary chondrocytes HC-OA (Cell...
The complete capitalisation of vegetal raw materials as renewable natural resources is a current study direction that based on the diversification active compounds identified and isolated from certain sources, effectiveness extracting technologies definition relevant spectrum biological action.The focused highlighting antioxidant effect induced by components winemaking waste (TES extract) in dermo-epidermal cells.The tests was performed normal fibroblast human keratinocytic cell lines,...
Objective: We aim to evaluate the potential interaction of two insect hemolymph peptides, MDF3 and MDF4, with human androgen receptor, on premise that proliferative effects peptides are (at least in part) a consequence AR binding. Methods: employed bioinformatic approach for prediction protein-peptide peptide aggregation, using various silico on-line tools such as docking servers, aggregation servers visualization analysis software order our results. Results: Our evaluation indicates MDF4...