A5020803226- Hemoglobinopathies and Related Disorders
- Lymphoma Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Iron Metabolism and Disorders
- Blood groups and transfusion
- Medical Imaging and Pathology Studies
- Ovarian cancer diagnosis and treatment
- T-cell and Retrovirus Studies
- Chronic Myeloid Leukemia Treatments
- Immunodeficiency and Autoimmune Disorders
- Eosinophilic Disorders and Syndromes
- Folate and B Vitamins Research
- Clinical Laboratory Practices and Quality Control
- Immune Cell Function and Interaction
- Sarcoidosis and Beryllium Toxicity Research
- Abdominal Trauma and Injuries
- Bone and Joint Diseases
- Porphyrin Metabolism and Disorders
- Electrolyte and hormonal disorders
- Occupational and environmental lung diseases
- IgG4-Related and Inflammatory Diseases
- Lysosomal Storage Disorders Research
- Erythrocyte Function and Pathophysiology
- Autopsy Techniques and Outcomes
Tel Aviv University
1997-2020
Rabin Medical Center
1999-2019
Comprehensive Clinical Research
2010
Institute of Hydrology of the Slovak Academy of Sciences
2006
Institute of Cancer Research
2000
Cancer Research And Biostatistics
2000
In vitro work suggests that cytokines may be important modulators of the cytotoxic effects paclitaxel and subsequent drug resistance. This has been investigated in vivo patients with ovarian cancer by ELISA. There was consistently elevated expression IL-6 IL-8 but not MCP-1, IL-1beta, IL-2, GM-CSF or TNFalpha. Peritoneal fluid concentrations IL-6, MCP-1 were two to three logs greater than serum concentrations. Elevated correlated a poor final outcome (P = 0.039), increased initial response...
Essential thrombocythemia (ET) is often associated with thrombotic and hemorrhagic complications, mostly at platelet counts exceeding 600 x 10(9)/L. There are, however, a few reports of such complications in ET considerably lower levels the therapeutic approach to affected patients relatively low still controversial. In present study, first directly address issue hemostatic manifestations counts, we have determined lowest 56 consecutive patients. Clinical related were recorded 46 (82%) Of...
Deferasirox is a recently approved oral iron chelator for treatment of patients with transfusion-related overload. Although renal function disturbances were recognized, proximal tubulopathy was not addressed in published safety reports deferasirox. subclinical described β-thalassemia homozygotes, overt Fanconi kidney an established disease complication. We describe 4 cases out 50 children and adults transfusion-dependent β-thalassemia, treated deferasirox overload, who developed clinically...
Cancer antigen 125 (CA 125) is a glycoprotein expressed in normal tissues originally derived from coelomic epithelia such as peritoneum, pleura, pericardium, fallopian tubes and endometrium. Serum CA levels are elevated various benign malignant conditions that involve stimulation of these tissues. Although have been reported patients with non-Hodgkin's lymphoma (NHL), its role prognostic factor remained uncertain. In this study, serum were measured prospectively 108 consecutive NHL: at...
Abstract: Objectives : Patients with malignancies have an increased prevalence of antiphospholipid antibodies (APA). The aim this study was to determine the IgG, IgM, and IgA anticardiolipin (aCL) anti‐beta‐2 glycoprotein I (anti‐ β 2‐GPI) in patients non‐Hodgkin's lymphoma (NHL), investigate their clinical prognostic significance. Methods group included 86 NHL. Enzyme‐linked immunosorbent assay kits were used measure concentrations aCL anti‐ 2‐GPI, coagulation tests, lupus anticoagulant...
Summary Splenectomy is considered therapeutic in various non‐malignant haematologic diseases. Adverse events ‒ specifically infections and thromboembolism are not extensively documented the paediatric population, maintaining concern over risks‐versus‐benefits of procedure. We studied a cohort haematology patients undergoing splenectomy between 1977 2015 to determine short‐ long‐term complications. summarised all clinic our major Israeli tertiary centre for reasons, capturing infectious...
Abstract A 60‐year‐old woman with disseminated small cell carcinoma of the lung and hemophagocytosis by metastatic cells in bone marrow is presented, it first clinicopathologic report on phagocytosis erythrocytes tumor concordance a recently described evidence macrophage origin lung.
Patients with β-thalassemia major (TM) may have tubular dysfunction and glomerular dysfunction, primarily hyperfiltration, based on eGFR. Assessment of GFR serum creatinine concentration overestimate in these patients. This study sought to determine by using inulin clearance compare it measured (Ccr) eGFR.Patients followed up an Israeli thalassemia clinic who had been regularly transfused for years treated deferasirox were included the study. They studied clearance, Ccr, CKD Epidemiology...
A high prevalence of human T-lymphotropic virus type I (HTLV-I) infection among Israeli Jews was previously reported. In the present study, screening for HTLV-I expanded to 10 ethnic groups. antibodies were tested by particle agglutination assay, ELISA, and Western blot as a confirmatory method. The proviral genome nested PCR with tax primers (SK43/SK44 Tr101/Tr102). tests carried out in all seropositive subjects seronegative family members seropositives Iranian population. Sixty-eight 1,679...
Thromboembolic complications and decrease in protein C S have been observed patients while receiving combination chemotherapy for breast cancer. We investigated whether initial cytotoxic treatment of non-Hodgkin's lymphoma (NHL) Hodgkin's disease (HD) is also associated with changes these anticoagulant parameters. For this purpose 25 intermediate to high grade NHL seven HD, undergoing primary drugs were evaluated at three time-points: pre-therapy, mid-therapy post-therapy. In contrast the...
The plain films of 37 patients under age 18 with surgically and pathologically proven non perforated (16/37) ruptured (21/37) appendicitis were reviewed in order to determine the ability film specify perforation. Perforation was suggested when one or more following six findings clearly defined: 1. Acute small bowel obstruction. 2. Extraluminal gas. 3. Mass right lower quadrant. 4. Colon cut-off sign at hepatic flexure. 5. Fecalith. 6. Obliteration pelvic fat planes. This approach resulted a...