Lei Chen

ORCID: 0000-0002-9916-0009
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About
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Research Areas
  • Cancer-related molecular mechanisms research
  • melanin and skin pigmentation
  • Molecular Biology Techniques and Applications
  • Meat and Animal Product Quality
  • Genetic and phenotypic traits in livestock
  • Adipose Tissue and Metabolism
  • Protein Hydrolysis and Bioactive Peptides
  • Rangeland Management and Livestock Ecology
  • Immune Cell Function and Interaction
  • N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
  • Catalytic Cross-Coupling Reactions
  • Cancer Diagnosis and Treatment
  • Biochemical Analysis and Sensing Techniques
  • Genetic diversity and population structure
  • Cyclopropane Reaction Mechanisms
  • Medical Imaging and Pathology Studies
  • Cancer Genomics and Diagnostics
  • RNA Research and Splicing
  • Chromosomal and Genetic Variations

Shihezi University
2017-2024

Ministry of Agriculture and Agro Based Industry
2022

Ministère de l'Agriculture et de la Souveraineté alimentaire
2022

Xinjiang Academy of Animal Science
2022

Ministry of Agriculture Livestock and Fisheries
2022

Xinjiang Uygur Autonomous Region Education Department
2017

State Council of the People's Republic of China
2017

Understanding the genetic mechanisms of phenotypic variation in hybrids between domestic animals and their wild relatives may aid germplasm innovation. Here, we report high-quality genome assemblies a male Pamir argali ( O . ammon polii , 2 n = 56), female Tibetan sheep aries 54), hybrid sheep, high-throughput sequencing 425 ovine animals, including sheep. We detected genomic synteny Chromosome two acrocentric chromosomes argali. revealed consistent satellite repeats around chromosome...

10.1101/gr.276769.122 article EN cc-by-nc Genome Research 2022-08-10

A novel organocatalytic olefinic carbon-sulfur bond forming reaction was developed. Under the catalysis of 10 mol% stable N-heterocyclic carbene, thiols undergo direct nucleophilic substitution with gem-difluoroalkenes to produce α-fluorovinyl thioethers in high yields excellent Z-selectivity. In this process, bases are not necessary.

10.1039/c7ob00599g article EN Organic & Biomolecular Chemistry 2017-01-01

Beef flavor plays a crucial role in consumer preference, yet research on this trait has been limited by past technological constraints. Intramuscular fat (IMF) is key determinant of beef quality, influencing taste, marbling, and overall flavor. Xinjiang brown cattle (XBC), an indigenous breed from northern Xinjiang, China, presents significant variation meat with IMF content ranging 0.2 % to 4.3 within the population. This suggests strong potential for breeding improvement. In study, we...

10.1016/j.fochms.2024.100220 article EN cc-by-nc-nd Food Chemistry Molecular Sciences 2024-08-30

Objective: With the rapid development of proteomics sequencing and RNA technology, multi-omics analysis has become a current research hotspot. Our previous study indicated that Xinjiang brown cattle have better meat quality than Kazakh cattle. In this study, were used as objects.Methods: Proteome technology to analyze proteome transcriptome longissimus dorsi muscle two breeds adult steers (n = 3).Results: project, 22,677 transcripts 1,874 proteins identified through quantitative proteome. By...

10.5713/ab.20.0751 article EN cc-by Animal Bioscience 2021-02-15

With the gradual completion of human genome project, proteomes have gained extremely important value in fields disease and biological process research. In our previous research, we performed transcriptomic analyses longissimus dorsi tissue from Kazakh cattle Xinjiang brown conducted in-depth studies on muscles both species through epigenetics. However, it is unclear whether differentially expressed proteins regulate muscle production development. this study, a proteomic analysis was by using...

10.1080/10495398.2021.2019756 article EN cc-by-nc-nd Animal Biotechnology 2021-12-30
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