A5057607340- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Glaucoma and retinal disorders
- Retinal and Optic Conditions
- Retinal Development and Disorders
- Ocular Diseases and Behçet’s Syndrome
- Retinal and Macular Surgery
- Optical Coherence Tomography Applications
- Retinopathy of Prematurity Studies
- Drug-Induced Ocular Toxicity
- Salivary Gland Disorders and Functions
- Stress Responses and Cortisol
- Dermatological and Skeletal Disorders
- Mitochondrial Function and Pathology
- Ophthalmology and Visual Impairment Studies
- Cerebrovascular and Carotid Artery Diseases
- Genetic and Kidney Cyst Diseases
- Peripheral Artery Disease Management
- Oral Health Pathology and Treatment
- Curcumin's Biomedical Applications
- Neurological Disease Mechanisms and Treatments
- Ophthalmology and Visual Health Research
- Advanced Glycation End Products research
- Optical Imaging and Spectroscopy Techniques
- Amyloidosis: Diagnosis, Treatment, Outcomes
Fondazione G.B. Bietti
2018-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2019-2025
International Flame Research Foundation
2021
Hôpital Intercommunal de Créteil
2015-2016
Université Paris-Est Créteil
2015-2016
IRCCS Ospedale San Raffaele
2016
University of Campania "Luigi Vanvitelli"
2015-2016
University of Naples Federico II
2015-2016
Università Cattolica del Sacro Cuore
2011
Purpose . To analyze optical coherence tomography angiography (OCTA) findings in eyes with central serous chorioretinopathy (CSC) and to compare them those obtained multimodal imaging. Methods A series of consecutive patients diagnosed CSC, underwent OCTA imaging, including spectral domain OCT, fluorescein, indocyanine green angiography. images were performed at three main depth intervals: automatically segmented outer retina, manually adjusted choriocapillaris. Results Thirty-three 32...
To evaluate the size of type 1 choroidal neovascularization (CNV) in neovascular AMD by optical coherence tomography angiography (OCTA) and to compare with indocyanine green (ICGA).Patients diagnosed CNV underwent multimodal imaging fluorescein (FA), ICGA, spectral-domain (SD)-OCT, OCTA. Lesion was measured both on OCTA at choriocapillaris level "select area" "vessel functions, incorporated AngioVue software ICGA intermediate late phases, two masked independent readers.Nineteen eyes 17...
Purpose: To describe and interpret "choroidal caverns," an unreported optical coherence tomography (OCT) finding in the choroid of patients with geographic atrophy (GA) secondary to atrophic AMD. Methods: Retrospective analysis GA. Main outcomes measures included estimation prevalence choroidal caverns, their localization relation retinal-choroidal structures by reviewing medical records multimodal imaging. Results: One hundred twenty consecutive (mean age 80.5 ± 8.61 years) were included....
To explore the potential relationships between macular vascular network and different adaptive optics (AO) metrics in patients with type 1 diabetes mellitus (DM1) no signs (NoDR) or mild non-proliferative diabetic retinopathy (NPDR).Observational cross-sectional study.Forty eyes of consecutive DM1 (12 NoDR 28 NPDR) 10 healthy age-matched control subjects were included. All controls imaged using AO retinal camera PLEX Elite 9000 optical coherence tomography (OCT) angiography (OCTA). The...
To compare luminal and stromal area of the choroid in eyes with drusen reticular pseudodrusen (RPD) to investigate their changes over 24 months.In RPD control subjects, total choroidal, were measured on optical coherence tomography B-scans converted binary images, at baseline after months.Eighteen 18 subjects for each group included. In RPD, we found reduction mean choroidal (p=0.0005 p<0.0001, respectively), (p=0.003 respectively) (p=0.007 p=0.0002, from month 24; no change ratio between...
To investigate the effects of eplerenone compared to observation in treatment acute central serous chorioretinopathy (CSC).Charts consecutive patients with a diagnosis CSC (visual symptoms < 12 weeks) were reviewed. Included divided into group (treated eplerenone) and control (observation). Main outcome measures included changes best-corrected visual acuity (BCVA), macular thickness (CMT), height subretinal fluid (SRF) subfoveal choroidal (CT) at 1 3 months two groups.Fifteen eyes 15 (2...
Abstract The aim of this paper was to distinguish the appearance cysts and non-perfusion areas (NPAs) in diabetic macular edema (DME) using two different Optical Coherence Tomography Angiography (OCTA) devices. In study, patients underwent OCTA AngioVue XR Avanti Spectral Domain (SD) PLEX Elite 9000 Swept-Source (SS) OCTA. Foveal extrafoveal regions interest (ROI), defined as any area with an altered flow signal comparing surrounding retina, were selected superficial deep capillary plexus...
Purpose: To present data on clinical response to eplerenone over a 1-year period in patients with central serous chorioretinopathy (CSC), and evaluate optical coherence tomography (OCT) variables as predictors of treatment at 3- 12-month follow-up visits. Methods: Patients acute or chronic CSC treated were retrospectively included. Clinical imaging characteristics recorded baseline the 3-month Changes from quantitative measurements calculated each follow-up. Logistic regression analysis was...
To analyze different clinical and anatomical features in treatment-naïve non-exudative macular neovascularizations (MNVs) secondary to age-related disease (AMD).In this retrospective longitudinal study with a minimum follow-up of 1 year, 31 eyes 28 consecutive AMD patients (mean age 75 ± 9 years) MNV were enrolled. Patients divided in: short-term activated group (exudation before 6-month) quiescent (per definition no exudation during 6-month follow-up) showing or late activation...
Purpose: To assess the impact of histogram adjustments and binarization thresholding selection on quantitative measurements diabetic macular ischemia using optical coherence tomography angiography (OCTA). Methods: Patients with retinopathy (DR) who had swept-source OCTA imaging obtained were enrolled. An additional group 15 healthy control subjects was included for comparison. Previously used brightness/contrast changes thresholds applied to original images obtain compare different binarized...
Purpose: To characterize structural and clinical alterations preceding the diffuse macular atrophy in extensive with pseudodrusen (EMAP) their evolution toward atrophic changes. Methods: A retrospective chart review was performed of patients early-onset reticular (i.e., pre-EMAP) younger than 55 years EMAP foveal sparing. Patients were included if they had complete medical records multimodal imaging. Results: total 12 reviewed, whom 4 (7 eyes) presented a pre-EMAP stage, characterized by...
To investigate fellow eyes of newly diagnosed unilateral exudative Type 3 (T3) macular neovascularization (MNV) patients by assessing the presence and progression a preclinical neovascular component during 3-year follow-up.This is longitudinal study involving three retinal referral centers. Patients affected treatment-naive T3 MNV were enrolled.Twenty-four 24 (79 ± 6 years old) enrolled. Nine (37%) displayed nonexudative at baseline that developed exudation after mean 9 months. Fifteen did...
<h3>Purpose</h3> To compare choroidal thickness maps (CMs) in patients with non-exudative age-related macular degeneration (AMD) and control subjects using swept source optical coherence tomography (Swept-OCT). <h3>Methods</h3> CMs were automatically measured the different Early Treatment of Diabetic Retinopathy Study (ETDRS) sectors eyes early AMD (early AMD) (large soft drusen: group 1; reticular pseudodrusen: 2 variable combination large drusen 3), late AMD/geographic atrophy (GA) (late...
To describe retinal pigment epithelium (RPE) aperture and to generate hypotheses about pathogenesis of this previously unreported finding in the evolution avascular detachment (PED) secondary age-related macular degeneration.Medical records multimodal imaging results from 10 patients with RPE apertures were reviewed between January 2009 December 2014 by 2 institutions. Main outcome measures analysis characteristics, including areas PED diameters, their temporal course. Lesions preceding...
Purpose: To assess demographic, metabolic, and imaging predictors influencing microvasculature photoreceptors changes over a 4-year follow-up in type 1 diabetes mellitus (DM1). Methods: This prospective cohort study enrolled patients with DM1 mild non-proliferative diabetic retinopathy. Complete medical records, glycosylated hemoglobin (HbA1c), optical coherence tomography angiography, adaptive optics were collected for the 4 years of follow-up. The main outcome measures included perfusion...
Purpose: To evaluate the impact of optical coherence tomography (OCT) phenotypes preceding atrophy related to age-related macular degeneration (AMD) on progression atrophic lesions. Methods: In this observational retrospective cohort study, a total 70 eyes 60 consecutive patients with intermediate AMD minimum follow-up 24 months were included. The was quantified using fundus autofluorescence, also considering directionality as centrifugal and centripetal rates. Main outcome measures...
Purpose: To assess differences in choriocapillaris (CC) and macular neovascularization (MNV) optical coherence tomography angiography quantitative parameters between long-term persistently nonexudative MNVs (NE-MNVs) activated NE-MNVs age-related degeneration. Methods: Age-related degeneration patients with treatment-naïve >2 years of follow-up no evidence exudation within the first 6 months from diagnosis were retrospectively recruited. Two groups considered according to occurrence (EX...