Alexandra Mière

ORCID: 0000-0003-4123-8210
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About
Contact & Profiles
Research Areas
  • Retinal Diseases and Treatments
  • Retinal Imaging and Analysis
  • Retinal and Optic Conditions
  • Glaucoma and retinal disorders
  • Retinal and Macular Surgery
  • Retinal Development and Disorders
  • Ocular Diseases and Behçet’s Syndrome
  • Cerebrovascular and Carotid Artery Diseases
  • Optical Coherence Tomography Applications
  • Renal and Vascular Pathologies
  • Hemoglobinopathies and Related Disorders
  • Intraocular Surgery and Lenses
  • Peripheral Artery Disease Management
  • Vascular Malformations Diagnosis and Treatment
  • Acute Ischemic Stroke Management
  • Drug-Induced Ocular Toxicity
  • Neurological Complications and Syndromes
  • Cerebral Venous Sinus Thrombosis
  • Dermatological and Skeletal Disorders
  • Ophthalmology and Visual Impairment Studies
  • melanin and skin pigmentation
  • RNA regulation and disease
  • Systemic Lupus Erythematosus Research
  • Blood groups and transfusion
  • Amyloidosis: Diagnosis, Treatment, Outcomes

Hôpital Intercommunal de Créteil
2016-2025

Université Paris-Est Créteil
2016-2025

Paris-Est Sup
2016-2023

Université Paris Cité
2016-2023

Vita-Salute San Raffaele University
2022

Università Cattolica del Sacro Cuore
2022

Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2022

Laboratoire Images, signaux et systèmes intelligents
2019-2021

To establish a normative database for vascular density (VD) and foveal avascular zone (FAZ) at the superficial (SCP) deep capillary plexus (DCP) in healthy subjects with optical coherence tomography (OCT) angiography.The study was retrospective chart review of patients who had undergone OCT angiography imaging. A 3- × 3-mm area, centered on fovea, scanned all eyes. The automated segmentation allowed separate analysis SCP, DCP, comprehensive C-scan including both layers. On obtained images,...

10.1167/iovs.15-18793 article EN cc-by-nc-nd Investigative Ophthalmology & Visual Science 2016-07-13

Optical coherence tomography angiography is a novel and noninvasive technique for imaging retinal microvasculature by detecting changes in reflectivity that related to blood flow. The purpose of this study was describe Type 2 neovascularization characteristics age-related macular degeneration using optical angiography.Fourteen eyes 14 consecutive patients with were prospectively included. All underwent complete ophthalmological examination, including color infrared fundus photography,...

10.1097/iae.0000000000000773 article EN Retina 2015-10-06

Purpose . To analyze optical coherence tomography angiography (OCTA) findings in eyes with central serous chorioretinopathy (CSC) and to compare them those obtained multimodal imaging. Methods A series of consecutive patients diagnosed CSC, underwent OCTA imaging, including spectral domain OCT, fluorescein, indocyanine green angiography. images were performed at three main depth intervals: automatically segmented outer retina, manually adjusted choriocapillaris. Results Thirty-three 32...

10.1155/2015/134783 article EN cc-by Journal of Ophthalmology 2015-01-01

To study choriocapillaris (CC) flow in eyes with Type 3 neovascularization (NV) and age-related macular degeneration, using optical coherence tomography angiography analysis.In this multicenter, retrospective, observational study, we collected data from 21 patients unilateral NV based on clinical examination, structural tomography, fluorescein when available. An additional group of 20 nonneovascular degeneration 1 or 2 due to was included for comparison. En face imaging (3 × mm scans)...

10.1097/iae.0000000000002198 article EN Retina 2018-05-10

To report the imaging features of subretinal fibrosis secondary to exudative age-related macular degeneration (AMD) on optical coherence tomography angiography.All consecutive patients diagnosed with complicating AMD were imaged by color retinal photographs or multicolor imaging, fluorescein angiography, spectral domain tomography, and angiography. Eyes active observed during last 6 months compared those without any sign exudation >6 months.Forty-nine eyes 47 included. A blood flow inside...

10.1097/iae.0000000000000819 article EN Retina 2015-10-10

<h3>Purpose</h3> To analyse the morphological characteristics of polypoidal choroidal vasculopathy (PCV) on optical coherence tomography angiography (OCT-A). <h3>Methods</h3> Prospective study with consecutive patients affected PCV were included. All underwent a complete ophthalmological examination including fundus photography, fluorescein angiography, indocyanine green spectral-domain OCT and OCT-A. <h3>Results</h3> Twelve eyes 12 (mean age 72.6±10.5 years; 4 men 8 women) included for...

10.1136/bjophthalmol-2015-307892 article EN British Journal of Ophthalmology 2016-02-02

In Brief Purpose: To report the imaging features of Type 3 neovascularization secondary to exudative age-related macular degeneration on optical coherence tomography angiography (OCTA). Methods: All consecutive treatment-naive patients diagnosed with early-stage underwent by color retinal photographs or multicolor imaging, fluorescein angiography, indocyanine green spectral domain tomography, and OCTA. The OCTA were analyzed correlated findings conventional tomography. Results: A total 18...

10.1097/iae.0000000000000834 article EN Retina 2015-10-10

To describe the qualitative and quantitative changes in choroidal neovascularization (CNV) flow pattern after anti-vascular endothelial growth factor therapy, by optical coherence tomography angiography (OCTA).Consecutive patients with neovascular age-related macular degeneration underwent multimodal imaging, including OCTA at initial examination last visit. High-flow networks choriocapillaris segmentation of were qualitatively quantitatively analyzed baseline follow-up, to characterize...

10.1097/iae.0000000000001964 article EN Retina 2017-11-28

To evaluate the size of type 1 choroidal neovascularization (CNV) in neovascular AMD by optical coherence tomography angiography (OCTA) and to compare with indocyanine green (ICGA).Patients diagnosed CNV underwent multimodal imaging fluorescein (FA), ICGA, spectral-domain (SD)-OCT, OCTA. Lesion was measured both on OCTA at choriocapillaris level "select area" "vessel functions, incorporated AngioVue software ICGA intermediate late phases, two masked independent readers.Nineteen eyes 17...

10.1167/iovs.15-18830 article EN cc-by-nc-nd Investigative Ophthalmology & Visual Science 2016-07-13

To characterize the macular lesions in multifocal choroiditis using multimodal imaging (MMI) and to evaluate optical coherence tomography angiography (OCTA) distinguishing neovascular from inflammatory lesions.Retrospective review of medical records consecutive patients diagnosed with involvement, between September 2014 May 2016, were included. All underwent standard examination MMI, including fundus color photography, autofluorescence, fluorescein angiography, spectral domain tomography....

10.1097/iae.0000000000001617 article EN Retina 2017-03-31

To assess the ability of a deep learning model to distinguish between diabetic retinopathy (DR), sickle cell (SCR), retinal vein occlusions (RVOs) and healthy eyes using ultra-widefield colour fundus photography (UWF-CFP).In this retrospective study, UWF-CFP images patients with vascular disease (DR, RVO, SCR) controls were included. The used train multilayer convolutional neural network differentiate on different diseases controls. A total 224 included, which 169 55 cross-validation...

10.1136/bmjophth-2021-000924 article EN cc-by-nc BMJ Open Ophthalmology 2022-02-01

In Brief Purpose: To evaluate changes of vascular flow patients treated with intravitreal injections anti-vascular endothelial growth factor for macular edema secondary to retinal vein occlusion (RVO) optical coherence tomography angiography (OCTA). Methods: Patients RVO and factors were retrospectively evaluated. The following examinations performed before after treatment: best-corrected visual acuity, spectral domain tomography, fluorescein angiography, OCTA (Optovue, Inc). Automatic...

10.1097/iae.0000000000001334 article EN Retina 2016-09-29

To characterize quantitative optical coherence tomography angiography (OCT-A) parameters in active neovascular age-related macular degeneration (nAMD) patients under treatment and remission nAMD patients.Retrospective, cross-sectional study.One hundred four of whom 72 were Group 1 (active nAMD) 32 2 (remission based on SD-OCT (Spectral Domain OCT) qualitative morphology.This study was conducted at the Centre Ophtalmologique de l'Odeon between June 2016 December 2017. Eyes analyzed using...

10.1371/journal.pone.0205513 article EN cc-by PLoS ONE 2018-10-09

To describe the optical coherence tomography angiography (OCTA) characteristics of active myopic choroidal neovascularization (CNV) and to compare its sensitivity versus fluorescein spectral-domain tomography.Consecutive highly patients complicated with CNV were prospectively included. The OCTA features analyzed correlated findings conventional imaging (spectral-domain angiography).Twenty eyes 19 (mean age: 59.6 ± 12.1 years, mean spherical equivalent: -13.5 3.6 diopters) presenting both...

10.1097/iae.0000000000001456 article EN Retina 2017-01-12

Purpose: To describe and interpret "choroidal caverns," an unreported optical coherence tomography (OCT) finding in the choroid of patients with geographic atrophy (GA) secondary to atrophic AMD. Methods: Retrospective analysis GA. Main outcomes measures included estimation prevalence choroidal caverns, their localization relation retinal-choroidal structures by reviewing medical records multimodal imaging. Results: One hundred twenty consecutive (mean age 80.5 ± 8.61 years) were included....

10.1167/iovs.16-19083 article EN cc-by-nc-nd Investigative Ophthalmology & Visual Science 2016-05-10

Background. In recent years, deep learning has been increasingly applied to a vast array of ophthalmological diseases. Inherited retinal diseases (IRD) are rare genetic conditions with distinctive phenotype on fundus autofluorescence imaging (FAF). Our purpose was automatically classify different IRDs by means FAF images using algorithm. Methods. this study, patients retinitis pigmentosa (RP), Best disease (BD), Stargardt (STGD), as well healthy comparable group were used train multilayer...

10.3390/jcm9103303 article EN Journal of Clinical Medicine 2020-10-14

To predict improvement of best-corrected visual acuity (BCVA) 1 year after pars plana vitrectomy for epiretinal membrane (ERM) using artificial intelligence methods on optical coherence tomography B-scan images.Four hundred and eleven (411) patients with Stage II ERM were divided in a group (IM) (≥15 ETDRS letters VA recovery) no (N-IM) (<15 letters) according to 1-year 25-G internal limiting peeling. Primary outcome was the creation deep learning classifier (DLC) based images prediction....

10.1097/iae.0000000000003646 article EN Retina 2022-10-13

To evaluate the capacity of OCT angiography (OCTA) for detecting infraclinical lesions in parafoveal capillaries diabetic patients without retinopathy (DR).This prospective observational cross-sectional case-control study analyzed superficial and deep capillary plexuses (SCP DCP) on macular OCTA scans (3 × 3 mm) centered fovea. We compared 22 (34 eyes included) DR diagnosis color fundus photographs, with age- gender-matched nondiabetic controls (40 included). Qualitative analysis concerned...

10.1155/2017/8676091 article EN cc-by Journal of Ophthalmology 2017-01-01

To investigate the morphologic changes on optical coherence tomography angiography (OCTA) of treatment-naive Type 3 neovascularization secondary to exudative age-related macular degeneration after 1 year anti-vascular endothelial growth factor therapy.Consecutive patients diagnosed with early-stage were enrolled in this retrospective study. All underwent color fundus photographs/MultiColor (Heidelberg Engineering) imaging, fluorescein angiography, indocyanine green structural spectral domain...

10.1097/iae.0000000000001447 article EN Retina 2017-01-11
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