- Plant Physiology and Cultivation Studies
- Postharvest Quality and Shelf Life Management
- Horticultural and Viticultural Research
- Diet and metabolism studies
- Liver Disease Diagnosis and Treatment
- Gut microbiota and health
- Plant Reproductive Biology
- Diet, Metabolism, and Disease
- Adipose Tissue and Metabolism
- Birth, Development, and Health
- Probiotics and Fermented Foods
- Plant Pathogens and Fungal Diseases
- Coffee research and impacts
- Exercise and Physiological Responses
- Plant biochemistry and biosynthesis
- Inflammatory Bowel Disease
- Plant Gene Expression Analysis
- Muscle Physiology and Disorders
- Allergic Rhinitis and Sensitization
- Berry genetics and cultivation research
- Metabolomics and Mass Spectrometry Studies
- Cancer-related molecular mechanisms research
- Plant Molecular Biology Research
- Environmental Toxicology and Ecotoxicology
- Pregnancy and preeclampsia studies
Zhejiang University
2014-2024
The University of Tokyo
2013-2023
Fruit Research Institute
2020-2022
Zhejiang A & F University
2021
Chinese Academy of Medical Sciences & Peking Union Medical College
2021
Xiyuan Hospital
2021
National Clinical Research Center for Digestive Diseases
2021
National Medical Products Administration
2021
Central China Normal University
2015-2019
Heze Municipal Hospital
2019
Chinese bayberry (Myrica rubra Sieb. and Zucc.) is a subtropical evergreen tree originating in China. It has been cultivated southern China for several thousand years, annual production reached 1.1 million tons. The taste high level of health promoting characters identified the fruit recent years stimulated its extension introduction to Australia. A limited number co-dominant markers have developed applied genetic diversity identity studies. Here we report, first time, survey whole genome...
Abstract Background Peach ( Prunus persica (L.) Batsch) is one of the most important model fruits in Rosaceae family. Native to west China, where peach has been domesticated for more than 4,000 years, its cultivation spread from China Persia, Mediterranean countries and America. Chinese had a major impact on international breeding programs due high genetic diversity. In this research, we used 48 highly polymorphic SSRs, distributed over genome, investigate difference diversity, linkage...
Morella rubra, red bayberry, is an economically important fruit tree in south China. Here, we assembled the first high-quality genome for both a female and male individual of bayberry. The size was 313-Mb, 90% sequences were into eight pseudo chromosome molecules, with 32 493 predicted genes. By whole-genome comparison between association analysis bulked DNA samples from male, 59-Kb region determining identified located on distal end pseudochromosome 8, which contains abundant transposable...
Abstract ‘Chinese Cling’ is an important founder in peach breeding history due to the pleasant flavor. Genome-wide association studies (GWAS) combined with genomic selection are promising tools fruit tree breeding, as there a considerable time lapse between crossing and release of cultivar. In this study, 242 peaches from Shanghai germplasm were genotyped 145 456 single-nucleotide polymorphisms (SNPs). The six agronomic traits flesh color, shape, hairiness, flower type, pollen sterility,...
The aim of this study is to acquire information for future breeding efforts aimed at improving fruit quality via effects on aroma by comparing the diversity Chinese local peach cultivars across 10 samples three varieties (honey peach, yellow and flat peach). volatile components fruits were analyzed identified gas chromatography-ion mobility spectrometry (GC-IMS) combined with chromatography-mass (GC-MS), main flavor determined relative odor activity value (ROAV) principal component analysis...
In higher plants, light-harvesting chlorophyll a/b binding (Lhc) proteins play a vital role in photosynthetic processes and are widely involved the regulation of plant growth, development, response to abiotic stress. However, Lhc gene family has not been well identified peaches (Prunus persica L.). this study, 19 PpLhc genes were peach genome database, which unevenly distributed on all chromosomes. Phylogenetic analysis demonstrated that could be divided into three major subfamilies, each...
Peach gum polysaccharides have multiple biological functions, such as anti-oxidation, blood lipids reduction, and immune protection. However, their impact on the gut microbiota was still unclear. Here, high throughput sequencing used to study regulatory effects of peach polysaccharide using an in vitro fermentation model human microbiota. The results showed that species increased significantly α-diversity index (Sobs, Ace, Chao1, Shannon) decreased after compared with control group...
Jerusalem artichoke (JA) has the potential to attenuate lipid disturbances and insulin resistance (IR), but underlying mechanisms are not well understood. In present study, we elucidated physiological responses of JA intervention with a comprehensive transcriptome analysis. Wistar rats were fed control diet, 60 % fructose-enriched diet (FRU), or FRU 10 ( n 6–7) for 4 weeks. An oral glucose tolerance test was carried out on day 21. Liver samples collected biochemical global gene expression...
Abstract Gut microbiota is an essential factor in the shaping of intestinal immune system development and driving inflammation inflammatory bowel disease (IBD). We report effects microbe-host interactions underlying intervention using fine powder eggshell membrane (ESM) against IBD. ESM attenuated lipopolysaccharide-induced cytokine production promoted Caco-2 cell proliferation by up-regulating growth factors vitro . In a murine model dextran sodium sulphate-induced colitis, significantly...
Abstract Obesity is a major global lifestyle disorder associated with gut microbiota. The health benefits of eggshell membrane (ESM) have been shown in previous reports, particularly as regards microbiota composition. Here, we investigated whether ESM improves lipid metabolism and alters high‐fat diet‐fed mice. A total 20 C57BL/6J mice aged 6 weeks were given either control diet (CON), (HFD), or + 8% powder (HESM) for weeks. supplementation HFD‐fed reduced plasma triglycerides (TG) liver...
Abstract Background Cachexia is a life‐threatening condition observed in several pathologies, such as cancer or chronic diseases. Interleukin 10 ( Il10 ) gene transfer known to improve cachexia by downregulating Il6 . Here, we used an IL10‐knockout mouse model simulate and investigate the effects of eggshell membrane (ESM), resistant protein, on general pre‐cachexia symptoms, which particularly important for development therapeutics. Methods Five‐week‐old male C57BL6/J mice were fed AIN‐93G...
Diet-induced obesity is often associated with gut microbiota dysbiosis, lipid metabolism disorders, and chronic inflammation. Consumption of the pseudocereal Amaranthus mangostanus has multiple nutritional benefits. We investigated effects dietary amaranth on in high-fat (HF) diet-fed mice. C57BL/6J mice were provided either a control diet, HF or diet containing 10% powder (Ama) for 8 weeks. Ama supplementation significantly reduced levels triglycerides, total cholesterol, phospholipids...
Peach gummosis is one of the most widespread and destructive diseases. It causes growth stunting, yield loss, branch, trunk, tree death, becoming a restrictive factor in healthy sustainable development peach production. Although locus has been identified based on bi-parental quantitative trait (QTL) mapping, selection gummosis-resistant cultivars remains challenging due to lack resistant parents complexity an inducing factor. In this study, integrated approach genome-wide association study...
Chronological aging is commonly accompanied by chronic low-grade inflammation (or "inflammaging"), a contributor to the development of age-related diseases. Aging increases oxidative stress that accelerates telomere shortening, leading cell senescence and generation senescence-associated secretory phenotype (SASP) exacerbates inflammation. Dietary antioxidants may help protect telomeres attenuate Thyme essential oil (TEO), reported for its potency against neuroinflammation, was fed...